Dissipation Bounds All Steady-State Current Fluctuations.

Near equilibrium, small current fluctuations are described by a Gaussian distribution with a linear-response variance regulated by the dissipation. Here, we demonstrate that dissipation still plays a dominant role in structuring large fluctuations arbitrarily far from equilibrium. In particular, we prove a linear-response-like bound on the large deviation function for currents in Markov jump processes. We find that nonequilibrium current fluctuations are always more likely than what is expected from a linear-response analysis. As a small-fluctuations corollary, we derive a recently conjectured uncertainty bound on the variance of current fluctuations.

[1]  V. Lecomte,et al.  Thermodynamic Formalism for Systems with Markov Dynamics , 2007 .

[2]  Udo Seifert,et al.  Universal bounds on current fluctuations. , 2015, Physical review. E.

[3]  Dispersion for two classes of random variables: general theory and application to inference of an external ligand concentration by a cell. , 2015, Physical review. E, Statistical, nonlinear, and soft matter physics.

[4]  R. Kubo Statistical Physics II: Nonequilibrium Statistical Mechanics , 2003 .

[5]  Jorge Kurchan,et al.  Fluctuation theorem for stochastic dynamics , 1998 .

[6]  D. Sherrington Stochastic Processes in Physics and Chemistry , 1983 .

[7]  Udo Seifert,et al.  Stochastic thermodynamics of chemical reaction networks. , 2007, The Journal of chemical physics.

[8]  H. Qian,et al.  Thermodynamics of stoichiometric biochemical networks in living systems far from equilibrium. , 2005, Biophysical chemistry.

[9]  S. Varadhan,et al.  Asymptotic evaluation of certain Markov process expectations for large time , 1975 .

[10]  Yuhai Tu,et al.  The energy-speed-accuracy tradeoff in sensory adaptation , 2012, Nature Physics.

[11]  J P Garrahan,et al.  Dynamical first-order phase transition in kinetically constrained models of glasses. , 2007, Physical review letters.

[12]  Thomas Speck,et al.  Fluctuation-dissipation theorem in nonequilibrium steady states , 2009, 0907.5478.

[13]  A. C. Barato,et al.  A Formal View on Level 2.5 Large Deviations and Fluctuation Relations , 2014, 1408.5033.

[14]  C. Jarzynski Equalities and Inequalities: Irreversibility and the Second Law of Thermodynamics at the Nanoscale , 2011 .

[15]  T. Chou,et al.  Non-equilibrium statistical mechanics: from a paradigmatic model to biological transport , 2011, 1110.1783.

[16]  M. Esposito,et al.  Three faces of the second law. I. Master equation formulation. , 2010, Physical review. E, Statistical, nonlinear, and soft matter physics.

[17]  B. Derrida,et al.  of Statistical Mechanics : Theory and Experiment Non-equilibrium steady states : fluctuations and large deviations of the density and of the current , 2007 .

[18]  C. Maes,et al.  Minimum entropy production principle from a dynamical fluctuation law , 2006, math-ph/0612063.

[19]  Udo Seifert,et al.  Thermodynamic uncertainty relation for biomolecular processes. , 2015, Physical review letters.

[20]  Christian Maes,et al.  Fluctuations and response of nonequilibrium states. , 2009, Physical review letters.

[21]  H. P. Annales de l'Institut Henri Poincaré , 1931, Nature.

[22]  G. Crooks Entropy production fluctuation theorem and the nonequilibrium work relation for free energy differences. , 1999, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[23]  C. Maes,et al.  Canonical structure of dynamical fluctuations in mesoscopic nonequilibrium steady states , 2007, 0705.2344.

[24]  C. Maes,et al.  On and beyond entropy production: the case of Markov jump processes , 2007, 0709.4327.

[25]  David Mumford,et al.  Communications on Pure and Applied Mathematics , 1989 .

[26]  A. C. Barato,et al.  Universal bound on the Fano factor in enzyme kinetics. , 2015, The journal of physical chemistry. B.

[27]  Current fluctuations in the zero-range process with open boundaries , 2005, cond-mat/0504711.

[28]  W. Ebeling Stochastic Processes in Physics and Chemistry , 1995 .

[29]  D. Andrieux,et al.  Fluctuation Theorem for Currents and Schnakenberg Network Theory , 2005, cond-mat/0512254.

[30]  H. Touchette The large deviation approach to statistical mechanics , 2008, 0804.0327.

[31]  Massimiliano Esposito,et al.  Thermoelectric efficiency at maximum power in a quantum dot , 2008, 0808.0216.

[32]  K. Gawȩdzki,et al.  Fluctuation Relations for Diffusion Processes , 2007, 0707.2725.

[33]  Restoring a fluctuation-dissipation theorem in a nonequilibrium steady state , 2005, cond-mat/0511696.

[34]  Takahiro Harada,et al.  Equality connecting energy dissipation with a violation of the fluctuation-response relation. , 2005, Physical review letters.

[35]  A. Faggionato,et al.  Flows, currents, and cycles for Markov Chains: large deviation asymptotics , 2014, 1408.5477.

[36]  A. Faggionato,et al.  Large deviations of the empirical flow for continuous time Markov chains , 2012, 1210.2004.

[37]  U. Seifert Stochastic thermodynamics, fluctuation theorems and molecular machines , 2012, Reports on progress in physics. Physical Society.

[38]  J. Lebowitz,et al.  A Gallavotti–Cohen-Type Symmetry in the Large Deviation Functional for Stochastic Dynamics , 1998, cond-mat/9811220.

[39]  J. Parrondo,et al.  Generalized fluctuation-dissipation theorem for steady-state systems. , 2009, Physical review letters.

[40]  J. Vollmer,et al.  Fluctuating currents in stochastic thermodynamics. II. Energy conversion and nonequilibrium response in kinesin models. , 2015, Physical review. E, Statistical, nonlinear, and soft matter physics.

[41]  K. Mallick,et al.  Exact current statistics of the asymmetric simple exclusion process with open boundaries. , 2012, Physical review letters.

[42]  R. Fonck,et al.  Flows ! , 2003 .

[43]  Thomas Speck,et al.  Distribution of work in isothermal nonequilibrium processes. , 2004, Physical review. E, Statistical, nonlinear, and soft matter physics.