Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion*
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M. Prentki | R. Zechner | N. Ruderman | V. Poitout | S. Madiraju | G. Haemmerle | M. Peyot | C. Guay | M. Latour | J. Lamontagne | R. Lussier | M. Pineda | É. Joly | E. Joly
[1] J. Leahy,et al. Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass , 2009, Diabetologia.
[2] L. Eliasson,et al. A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis , 2009, Diabetologia.
[3] M. Prentki,et al. The islet β-cell: fuel responsive and vulnerable , 2008, Trends in Endocrinology & Metabolism.
[4] R. Takayanagi,et al. The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets. , 2008, The Journal of clinical endocrinology and metabolism.
[5] B. Kemp,et al. Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. , 2008, Molecular endocrinology.
[6] Marc Prentki,et al. Glycerolipid metabolism and signaling in health and disease. , 2008, Endocrine reviews.
[7] K. Gillis,et al. Phosphorylation of SNAP-25 at Ser187 Mediates Enhancement of Exocytosis by a Phorbol Ester in INS-1 Cells , 2008, The Journal of Neuroscience.
[8] M. Prentki,et al. A Role for ATP-Citrate Lyase, Malic Enzyme, and Pyruvate/Citrate Cycling in Glucose-induced Insulin Secretion* , 2007, Journal of Biological Chemistry.
[9] J. R. McMillan,et al. Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy , 2007, Muscle & nerve.
[10] K. He,et al. The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells , 2007, Oncogene.
[11] R. Lehner,et al. Attenuation of Adipocyte Triacylglycerol Hydrolase Activity Decreases Basal Fatty Acid Efflux* , 2007, Journal of Biological Chemistry.
[12] R. Zechner,et al. Adipose Triglyceride Lipase and Hormone-sensitive Lipase Are the Major Enzymes in Adipose Tissue Triacylglycerol Catabolism* , 2006, Journal of Biological Chemistry.
[13] H. Mulder,et al. β-Cell Lipases and Insulin Secretion , 2006, Diabetes.
[14] M. Prentki,et al. Fatty Acid Signaling in the β-Cell and Insulin Secretion , 2006, Diabetes.
[15] J. Leahy,et al. Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling , 2006, Diabetologia.
[16] F. Ashcroft,et al. Deletion of Nicotinamide Nucleotide Transhydrogenase , 2006, Diabetes.
[17] E. Wagner,et al. Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase , 2006, Science.
[18] S. Müller,et al. Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5 , 2006, Nature Cell Biology.
[19] I. Artner,et al. Regulation of the insulin gene by glucose and fatty acids. , 2006, The Journal of nutrition.
[20] C. Holm,et al. Glucose-stimulated insulin secretion correlates with beta-cell lipolysis. , 2006, Nutrition, metabolism, and cardiovascular diseases : NMCD.
[21] S. Müller,et al. Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in β-cells , 2004, The Journal of cell biology.
[22] Frank Eisenhaber,et al. Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase , 2004, Science.
[23] H. Sul,et al. Desnutrin, an Adipocyte Gene Encoding a Novel Patatin Domain-containing Protein, Is Induced by Fasting and Glucocorticoids , 2004, Journal of Biological Chemistry.
[24] B. Ahrén,et al. Glucagon-like Peptide-1 and Islet Lipolysis , 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[25] A. Pshezhetsky,et al. Carboxylesterase 3 (EC 3.1.1.1) Is a Major Adipocyte Lipase* , 2004, Journal of Biological Chemistry.
[26] P. Rorsman,et al. Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact. , 2004, Endocrinology.
[27] M. Prentki,et al. Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1. , 2004, Diabetes.
[28] P. Rorsman,et al. Palmitate increases L‐type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic β‐cells , 2004, The Journal of physiology.
[29] M. Prentki,et al. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. , 2004, Diabetes.
[30] F. Sundler,et al. A Novel Hormone-sensitive Lipase Isoform Expressed in Pancreatic β-Cells* , 2004, Journal of Biological Chemistry.
[31] H. Mulder,et al. Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion. , 2004, Diabetes.
[32] M. Prentki,et al. Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. , 2003, Endocrinology.
[33] S. Tilghman,et al. Glyceroneogenesis and the Triglyceride/Fatty Acid Cycle* , 2003, Journal of Biological Chemistry.
[34] M. Prentki,et al. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. , 2002, Diabetes.
[35] G. Sharp,et al. Glucose‐stimulated signaling pathways in biphasic insulin secretion , 2002, Diabetes/metabolism research and reviews.
[36] R. Zechner,et al. Hormone-sensitive Lipase Deficiency in Mice Causes Diglyceride Accumulation in Adipose Tissue, Muscle, and Testis* , 2002, The Journal of Biological Chemistry.
[37] Thomas C. Südhof,et al. β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs , 2002, Cell.
[38] M. Prentki,et al. The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets. , 2002, Metabolism: clinical and experimental.
[39] J. Gagliardino,et al. Changes induced by sucrose administration on glucose metabolism in pancreatic islets in normal hamsters. , 2001, The Journal of endocrinology.
[40] M. Jensen,et al. Lipid metabolism during fasting. , 2001, American journal of physiology. Endocrinology and metabolism.
[41] P. Arner,et al. The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose. , 2001, Diabetes.
[42] M. Prentki,et al. A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice. , 2001, Diabetes.
[43] D. Eizirik,et al. Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. , 2001, Diabetes.
[44] J. Deeney,et al. Glucagon-Like Peptide 1 Stimulates Lipolysis in Clonal Pancreatic β-Cells (HIT) , 2001 .
[45] M. Prentki,et al. Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell* , 2000, The Journal of Biological Chemistry.
[46] J. Henquin,et al. Triggering and amplifying pathways of regulation of insulin secretion by glucose. , 2000, Diabetes.
[47] M. Prentki,et al. Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)* , 2000, The Journal of Biological Chemistry.
[48] M. Prentki,et al. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. , 2000, Diabetes.
[49] P. Rorsman,et al. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells. , 1999, Diabetes.
[50] J. McGarry,et al. A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion. , 1998, The Journal of clinical investigation.
[51] M. Dunne,et al. Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets. , 1998, Diabetes.
[52] M. Linder,et al. SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway. , 1998, Molecular biology of the cell.
[53] C. Newgard,et al. β-Cell Function in Normal Rats Made Chronically Hyperleptinemic by Adenovirus-Leptin Gene Therapy , 1997, Diabetes.
[54] J. McGarry,et al. The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. , 1997, The Journal of clinical investigation.
[55] T. Südhof,et al. Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. , 1996, Biochemical and biophysical research communications.
[56] J. McGarry,et al. Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. , 1996, The Journal of clinical investigation.
[57] M. Solimena,et al. ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules. , 1996, The EMBO journal.
[58] G. Lopaschuk,et al. Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts. , 1991, The Journal of biological chemistry.
[59] S. Bonner-Weir,et al. REPRODUCIBLE HIGH YIELD OF RAT ISLETS BY STATIONARY IN VITRO DIGESTION FOLLOWING PANCREATIC DUCTAL OR PORTAL VENOUS COLLAGENASE INJECTION1 , 1987, Transplantation.
[60] J. Hutton,et al. Nucleotide and bivalent cation specificity of the insulin-granule proton translocase. , 1983, The Biochemical journal.
[61] P. Hahn,et al. Development of brown and white adipose tissue. , 1975, Journal of lipid research.
[62] M. Vaughan. The production and release of glycerol by adipose tissue incubated in vitro. , 1962, The Journal of biological chemistry.