Age and Persistent Use of Cardiovascular Medication After Acute Coronary Syndrome: Results from Medication Applied and Sustained Over Time

OBJECTIVES: To describe the persistent use of evidence‐based cardiovascular medications (EBCMs) 3 months after discharge from an acute coronary syndrome (ACS) event and patient‐reported reasons for nonpersistence across age groups.

[1]  P. Montgomery,et al.  Pill Count, Self-Report, and Pharmacy Claims Data to Measure Medication Adherence in the Elderly , 1998, The Annals of pharmacotherapy.

[2]  J. Newhouse,et al.  Medicare beneficiaries' knowledge of Part D prescription drug program benefits and responses to drug costs. , 2008, JAMA.

[3]  Matthew A Silva,et al.  Statin-related adverse events: a meta-analysis. , 2006, Clinical therapeutics.

[4]  Eva Kline-Rogers,et al.  Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing prospective, observational study. , 2004, The American journal of medicine.

[5]  Deepak L. Bhatt,et al.  Modifiable risk factors control and its relationship with 1 year outcomes after coronary artery bypass surgery: insights from the REACH registry , 2008, European heart journal.

[6]  L. Køber,et al.  Persistent Use of Evidence-Based Pharmacotherapy in Heart Failure Is Associated With Improved Outcomes , 2007, Circulation.

[7]  H. Krumholz,et al.  Early beta-blocker therapy for acute myocardial infarction in elderly patients. , 1999, Annals of internal medicine.

[8]  Elizabeth A. Schlenk,et al.  Effect of Personal and Cultural Beliefs on Medication Adherence in the Elderly , 2006, Drugs & aging.

[9]  J. Steiner,et al.  Dyslipidemia: Factors Related to Adherence to Statin Therapy , 2007, The Annals of pharmacotherapy.

[10]  R. Califf,et al.  Long-Term Adherence to Evidence-Based Secondary Prevention Therapies in Coronary Artery Disease , 2006, Circulation.

[11]  J. Avorn,et al.  Persistence of use of lipid-lowering medications: a cross-national study. , 1998, JAMA.

[12]  H. Krumholz,et al.  Effects of age on the quality of care provided to older patients with acute myocardial infarction. , 2003, The American journal of medicine.

[13]  D. Alter,et al.  Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction. , 2007, JAMA.

[14]  Deepak L. Bhatt,et al.  Comparisons of guideline-recommended therapies in patients with documented coronary artery disease having percutaneous coronary intervention versus coronary artery bypass grafting versus medical therapy only (from the REACH International Registry). , 2007, The American journal of cardiology.

[15]  J. Steiner,et al.  A Systematic Review of the Literature , 2019, HIV/AIDS and Adolescents.

[16]  J. Hugtenburg,et al.  Initial phase of chronic medication use; patients' reasons for discontinuation. , 2006, British journal of clinical pharmacology.

[17]  K. Alexander,et al.  Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence. , 2007, The American journal of geriatric pharmacotherapy.

[18]  K. Eagle,et al.  Impact of Combination Evidence-Based Medical Therapy on Mortality in Patients With Acute Coronary Syndromes , 2004, Circulation.

[19]  Cathy Schoen,et al.  Physician–Patient Communication About Prescription Medication Nonadherence: A 50-state Study of America’s Seniors , 2007, Journal of General Internal Medicine.

[20]  B. Horne,et al.  Usefulness of in-hospital prescription of statin agents after angiographic diagnosis of coronary artery disease in improving continued compliance and reduced mortality. , 2001, The American journal of cardiology.

[21]  J. Tardif,et al.  Heart rate slowing versus other pharmacological antianginal strategies. , 2006, Advances in cardiology.

[22]  S. Cook,et al.  Erectile dysfunction in men with congenital heart disease. , 2008, The American journal of cardiology.

[23]  Harlan M Krumholz,et al.  Impact of medication therapy discontinuation on mortality after myocardial infarction. , 2006, Archives of internal medicine.

[24]  J. Hasford,et al.  Persistence with antihypertensive treatments: results of a 3-year follow-up cohort study , 2007, European Journal of Clinical Pharmacology.

[25]  H. Krumholz,et al.  Early -Blocker Therapy for Acute Myocardial Infarction in Elderly Patients , 1999, Annals of Internal Medicine.

[26]  H. Tilson,et al.  Aspirin use among adults aged 40 and older in the United States: results of a national survey. , 2007, American journal of preventive medicine.

[27]  R. Säljö,et al.  Reasons for adherence with antihypertensive medication. , 2000, International journal of cardiology.

[28]  J. Avorn,et al.  Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysis. , 2008, Journal of the American College of Cardiology.

[29]  M. Weinstein,et al.  Long-term persistence in use of statin therapy in elderly patients. , 2002, JAMA.

[30]  Harlan M. Krumholz,et al.  Prevalence, Predictors, and Outcomes of Premature Discontinuation of Thienopyridine Therapy After Drug-Eluting Stent Placement: Results From the PREMIER Registry , 2006, Circulation.

[31]  Gerardo Heiss,et al.  Long-term adherence with cardiovascular drug regimens. , 2006, American heart journal.

[32]  Fang Zhang,et al.  Cost-related medication nonadherence and spending on basic needs following implementation of Medicare Part D. , 2008, JAMA.

[33]  L. Pilote,et al.  Drug prescriptions after acute myocardial infarction: dosage, compliance, and persistence. , 2003, American heart journal.