Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products.

[1]  Chi-Hsien Liu,et al.  Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[2]  L. Rizza,et al.  Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation. , 2008, International journal of pharmaceutics.

[3]  R. Müller,et al.  Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[4]  Xiuli Wang,et al.  Solid lipid nanoparticles for pulmonary delivery of insulin. , 2008, International journal of pharmaceutics.

[5]  A. Attama,et al.  Effect of beeswax modification on the lipid matrix and solid lipid nanoparticle crystallinity , 2008 .

[6]  V. Patravale,et al.  Nanostructured lipid carrier (NLC) based gel of celecoxib. , 2008, International journal of pharmaceutics.

[7]  Ran Yin,et al.  Investigation of Nanostructured Lipid Carriers for Transdermal Delivery of Flurbiprofen , 2008 .

[8]  Kumar A. Shah,et al.  Solid lipid nanoparticles (SLN) of tretinoin: potential in topical delivery. , 2007, International journal of pharmaceutics.

[9]  B. Sarmento,et al.  Oral insulin delivery by means of solid lipid nanoparticles , 2007, International journal of nanomedicine.

[10]  B. Sarmento,et al.  Lipid-based colloidal carriers for peptide and protein delivery – liposomes versus lipid nanoparticles , 2007, International journal of nanomedicine.

[11]  A. Mauro,et al.  Solid lipid nanoparticles incorporating melatonin as new model for sustained oral and transdermal delivery systems. , 2007, Journal of nanoscience and nanotechnology.

[12]  P. Hayden,et al.  In vitro skin irritation test: Increasing the sensitivity of the EpiDerm skin irritation protocol evaluated in the ECVAM skin irritation validation study , 2007 .

[13]  R. Müller,et al.  Cetyl palmitate-based NLC for topical delivery of Coenzyme Q(10) - development, physicochemical characterization and in vitro release studies. , 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[14]  R. Müller,et al.  Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)--effects of formulation parameters on physicochemical stability. , 2007, International journal of pharmaceutics.

[15]  S. Zeng,et al.  Studies on oral absorption of stearic acid SLN by a novel fluorometric method. , 2007, Colloids and surfaces. B, Biointerfaces.

[16]  P. Giunchedi,et al.  Solid lipid nanoparticles (SLN) as carriers for the topical delivery of econazole nitrate: in‐vitro characterization, ex‐vivo and in‐vivo studies , 2007, The Journal of pharmacy and pharmacology.

[17]  H. Korting,et al.  Lipid nanoparticles for improved topical application of drugs for skin diseases. , 2007, Advanced drug delivery reviews.

[18]  M. Ricci,et al.  Solid lipid nanoparticles for targeted brain drug delivery. , 2007, Advanced drug delivery reviews.

[19]  W. Weyenberg,et al.  Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application. , 2007, International journal of pharmaceutics.

[20]  Claus-Michael Lehr,et al.  Nanoparticles--an efficient carrier for drug delivery into the hair follicles. , 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[21]  A. Mauro,et al.  Solid lipid nanoparticles: could they help to improve the efficacy of pharmacologic treatments for brain tumors? , 2007, Neurological research.

[22]  Zhirong Zhang,et al.  Lung-targeting delivery of dexamethasone acetate loaded solid lipid nanoparticles , 2007, Archives of pharmacal research.

[23]  C. Zouboulis,et al.  Cyproterone Acetate Loading to Lipid Nanoparticles for Topical Acne Treatment: Particle Characterisation and Skin Uptake , 2007, Pharmaceutical Research.

[24]  Huibi Xu,et al.  Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. , 2007, International journal of pharmaceutics.

[25]  G. Giammona,et al.  Nanostructured Lipid Carriers-Containing Anticancer Compounds: Preparation, Characterization, and Cytotoxicity Studies , 2007, Drug delivery.

[26]  L. Rizza,et al.  Evaluation of alternative strategies to optimize ketorolac transdermal delivery , 2006, AAPS PharmSciTech.

[27]  A F Thünemann,et al.  Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals. , 2006, International journal of pharmaceutics.

[28]  R. Müller,et al.  Solid lipid nanoparticles (SLN)--effects of lipid composition on in vitro degradation and in vivo toxicity. , 2006, Die Pharmazie.

[29]  Chong-K. Kim,et al.  Stabilization of all-trans retinol by loading lipophilic antioxidants in solid lipid nanoparticles. , 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[30]  R. Müller,et al.  The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents. , 2006, Die Pharmazie.

[31]  Huibi Xu,et al.  Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[32]  H. Fessi,et al.  Influence of the Formulation for Solid Lipid Nanoparticles Prepared with a Membrane Contactor , 2006, Pharmaceutical development and technology.

[33]  V. Patravale,et al.  Formulation and Evaluation of Nanostructured Lipid Carrier (NLC)–based Gel of Valdecoxib , 2006, Drug development and industrial pharmacy.

[34]  A. Momeni,et al.  The efficacy of topical cyproterone acetate alcohol lotion versus placebo in the treatment of the mild to moderate acne vulgaris: a double blind study. , 2005, Dermatology online journal.

[35]  B. Röder,et al.  Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[36]  R. Müller,et al.  Solid lipid nanoparticles (SLN) for topical drug delivery: incorporation of the lipophilic drugs N,N-diethyl-m-toluamide and vitamin K. , 2005, Die Pharmazie.

[37]  H. Fessi,et al.  Preparation of solid lipid nanoparticles using a membrane contactor. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[38]  R. Müller,et al.  SLN and NLC for topical delivery of ketoconazole , 2005, Journal of microencapsulation.

[39]  E. Souto,et al.  Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for Dermal Delivery , 2005 .

[40]  Shuangxi Liu,et al.  A new healthy sunscreen system for human: solid lipid nanoparticles as carrier for 3,4,5-trimethoxybenzoylchitin and the improvement by adding Vitamin E. , 2005, International journal of biological macromolecules.

[41]  C. Müller-Goymann,et al.  Novel nanoparticulate carrier system based on carnauba wax and decyl oleate for the dispersion of inorganic sunscreens in aqueous media. , 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[42]  C. Puglia,et al.  Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): in vitro and in vivo studies. , 2005, Journal of pharmaceutical sciences.

[43]  H. Korting,et al.  Glucocorticoid entrapment into lipid carriers--characterisation by parelectric spectroscopy and influence on dermal uptake. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[44]  R. Müller,et al.  Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[45]  R. Müller,et al.  Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages—impact of phagocytosis on viability and cytokine production , 2004, The Journal of pharmacy and pharmacology.

[46]  R. Müller,et al.  Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. , 2004, International journal of pharmaceutics.

[47]  R. Müller,et al.  Solid lipid nanoparticles for parenteral drug delivery. , 2004, Advanced drug delivery reviews.

[48]  M. Sznitowska,et al.  The choice of lipids and surfactants for injectable extravenous microspheres. , 2004, Die Pharmazie.

[49]  R. Müller,et al.  Structural Characterization of Q10-Loaded Solid Lipid Nanoparticles by NMR Spectroscopy , 2004, Pharmaceutical Research.

[50]  L. Kopelovich,et al.  Cyclooxygenases in the skin: pharmacological and toxicological implications. , 2003, Toxicology and applied pharmacology.

[51]  Yajiang Yang,et al.  Solid lipid nanoparticle and microemulsion for topical delivery of triptolide. , 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[52]  Rainer H Müller,et al.  The influence of solid lipid nanoparticles on skin hydration and viscoelasticity--in vivo study. , 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[53]  M. Trotta,et al.  Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique. , 2003, International journal of pharmaceutics.

[54]  Rainer H Müller,et al.  Cosmetic applications for solid lipid nanoparticles (SLN). , 2003, International journal of pharmaceutics.

[55]  M. Garcia‐Fuentes,et al.  Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules , 2003 .

[56]  R. Müller,et al.  Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. , 2002, Advanced drug delivery reviews.

[57]  S. Wissing,et al.  The influence of the crystallinity of lipid nanoparticles on their occlusive properties. , 2002, International journal of pharmaceutics.

[58]  R. Cavalli,et al.  Incorporation of cyclosporin A in solid lipid nanoparticles (SLN). , 2002, International journal of pharmaceutics.

[59]  R. Müller,et al.  Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[60]  Hong Yuan,et al.  Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization. , 2002, International journal of pharmaceutics.

[61]  J. Benoit,et al.  A Novel Phase Inversion-Based Process for the Preparation of Lipid Nanocarriers , 2002, Pharmaceutical Research.

[62]  R. Müller,et al.  Effect of lipid matrix and size of solid lipid nanoparticles (SLN) on the viability and cytokine production of macrophages. , 2002, International journal of pharmaceutics.

[63]  M. Schaller,et al.  Drug Targeting by Solid Lipid Nanoparticles for Dermal Use , 2002, Journal of drug targeting.

[64]  R. Müller,et al.  Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers. , 2001, Die Pharmazie.

[65]  S. Wissing,et al.  Investigations on the occlusive properties of solid lipid nanoparticles (SLN). , 2001, Journal of cosmetic science.

[66]  R. Müller,et al.  Surfactant, but not the size of solid lipid nanoparticles (SLN) influences viability and cytokine production of macrophages. , 2001, International journal of pharmaceutics.

[67]  K. Mäder,et al.  Solid lipid nanoparticles: production, characterization and applications. , 2001, Advanced drug delivery reviews.

[68]  R. Müller,et al.  Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles. , 2001, International journal of pharmaceutics.

[69]  S. Mesaros,et al.  Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel. , 2001, Clinical therapeutics.

[70]  H. Maibach,et al.  Effects of Skin Occlusion on Percutaneous Absorption: An Overview , 2001, Skin Pharmacology and Physiology.

[71]  R. Müller,et al.  Effect of solid lipid nanoparticles (SLN) on cytokine production and the viability of murine peritoneal macrophages. , 2000, Journal of microencapsulation.

[72]  R. Müller,et al.  Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. , 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[73]  M. Schäfer-Korting,et al.  Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[74]  M. Schäfer-Korting,et al.  Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targeting to the upper skin. , 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[75]  M. Schäfer-Korting,et al.  Solid lipid nanoparticles as drug carriers for topical glucocorticoids. , 2000, International journal of pharmaceutics.

[76]  R. Müller,et al.  Preserved solid lipid nanoparticles (SLN) at low concentrations do cause neither direct nor indirect cytotoxic effects in peritoneal macrophages. , 2000, International journal of pharmaceutics.

[77]  R. Müller,et al.  Influence of high pressure homogenisation equipment on nanodispersions characteristics. , 2000, International journal of pharmaceutics.

[78]  R. Müller,et al.  Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures. , 1999, International journal of pharmaceutics.

[79]  R. Müller,et al.  Solid lipid nanoparticles (SLN) as potential carrier for human use: interaction with human granulocytes , 1997 .

[80]  Rainer H. Müller,et al.  Cytotoxicity of Solid Lipid Nanoparticles as a Function of the Lipid Matrix and the Surfactant , 1997, Pharmaceutical Research.

[81]  R. Müller,et al.  Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles , 1996 .

[82]  B. Bergenståhl,et al.  Preparation of submicron drug particles in lecithin-stabilized o/w emulsions I. Model studies of the precipitation of cholesteryl acetate , 1992 .

[83]  Rainer H. Müller,et al.  Alkylcyanoacrylate drug carriers: II. Cytotoxicity of cyanoacrylate nanoparticles with different alkyl chain length , 1992 .

[84]  Alan Smith,et al.  Evaluation of poly(lactic acid) as a biodegradable drug delivery system for parenteral administration , 1986 .

[85]  B. Bivins,et al.  Clearance of 141C3-labeled microspheres from blood and distribution in specific organs following intravenous and intraarterial administration in beagle dogs. , 1980, Journal of pharmaceutical sciences.

[86]  P. Deluca,et al.  Distribution of radiolabeled subvisible microspheres after intravenous administration to beagle dogs. , 1978, Journal of pharmaceutical sciences.

[87]  B. Bivins,et al.  Physiological effects of subvisible microspheres administered intravenously to beagle dogs. , 1978, Journal of pharmaceutical sciences.

[88]  M. Vinardell,et al.  Alternative methods for eye and skin irritation tests: an overview. , 2008, Journal of pharmaceutical sciences.

[89]  J. Pardeike,et al.  Lipid nanoparticles (NLC) as novel carrier for cosmetics : Special features & state of commercialisation , 2007 .

[90]  A. Hommoss,et al.  Nanostructured lipid carrier : A delivery system with protective functions , 2006 .

[91]  E. Souto SLN and NLC for topical delivery of antifungals , 2005 .

[92]  P. Speiser,et al.  Optimization of Spray-Dried and -Congealed Lipid Micropellets and Characterization of Their Surface Morphology by Scanning Electron Microscopy , 2004, Pharmaceutical Research.

[93]  A. Coleman,et al.  AFM imaging of calixarene based solid lipid nanoparticles in gel matrices. , 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[94]  M. Schubert,et al.  Solvent injection as a new approach for manufacturing lipid nanoparticles--evaluation of the method and process parameters. , 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[95]  V Jenning,et al.  Encapsulation of retinoids in solid lipid nanoparticles (SLN). , 2001, Journal of microencapsulation.

[96]  S. Gohla,et al.  Scaling up feasibility of the production of solid lipid nanoparticles (SLN). , 2001, Die Pharmazie.

[97]  M. Prinsen An evaluation of the OECD proposal for the harmonised classification of eye irritants and corrosives , 1999 .

[98]  J. Fry Activation systems in tissue culture toxicity studies. , 1982, Toxicology.