The chemotherapy of protozoal infections of veterinary importance.

The use of drugs in domestic animals is dominated by considerations of cost-effectiveness and profitability. They are extensively used against coccidial infections of poultry where they are an important factor in intensive husbandry. Ionophore antibiotics, which dominate this field, may have applications in ruminants. Imidocarb is of therapeutic and prophylactic value against babesial infections anf there are new prospects for control of theileriasis. Effective drugs for the control of African trypanosomiasis are limited and attention is being given to alternative uses of available compounds.

[1]  G. Urquhart.  Application of immunity in the control of parasitic disease , 1980 .

[2]  R. G. Strout,et al.  Eimeria tenella: accumulation and retention of anticoccidial ionophores by extracellular sporozoites. , 1979, Experimental parasitology.

[3]  S. Hutner,et al.  Curative effects of the antipiroplasms amicarbalide and imidocarb on Trypanosoma brucei infection in mice. , 1979, The Journal of protozoology.

[4]  Ching C. Wang,et al.  Mode of anticoccidal action of arprinocid , 1979 .

[5]  C. Wang,et al.  Arprinocid, an inhibitor of hypoxanthine-guanine transport. , 1979, Biochemical pharmacology.

[6]  Horton Gm,et al.  Effects of amprolium and monensin on oocyst discharge, feed utilization, and ruminal metabolism of lambs with coccidiosis. , 1979 .

[7]  E. R. Young,et al.  Further studies on the uptake of tritiated nucleic acid precursors by Babesia spp. of cattle and mice , 1979 .

[8]  H. D. Chapman.  Studies on the sensitivity of recent field isolates of E. maxima to monensin. , 1979, Avian pathology : journal of the W.V.P.A.

[9]  H. Williams,et al.  Infection of the Mongolian gerbil with the cattle piroplasm Babesia divergens , 1979, Nature.

[10]  R. Miles.  Whither the Natural History Museum? , 1978, Nature.

[11]  McDougald Lr,et al.  Efficacy of monensin against coccidiosis in lambs. , 1978 .

[12]  P. L. Long,et al.  Coccidiosis in broilers: the effect of monensin and other anticoccidial drug treatments on oocyst output. , 1978, Avian pathology : journal of the W.V.P.A.

[13]  H. Bossche.  Chemotherapy of parasitic infections , 1978, Nature.

[14]  M. D. Ruff,et al.  Effect of the anticoccidial arprinocid on production, sporulation, and infectivity of Eimeria oocysts. , 1978, The Journal of parasitology.

[15]  Jeffers Tk.  Eimeria tenella: sensitivity of recent field isolants to monensin. , 1978 .

[16]  Fitzgerald Pr,et al.  Ovine coccidiosis: effect of the antibiotic monensin against Eimeria ninakohlyakimovae and other naturally occurring coccidia of sheep. , 1978 .

[17]  L. P. Joyner,et al.  The anticoccidial effects of amprolium, dinitolmide and monensin against Eimeria maxima, E. brunetti and E. acervulina with particular reference to oocyst sporulation , 1977, Parasitology.

[18]  E. R. Young,et al.  Possible in vitro test for screening drugs for activity against Babesia and other blood protozoa , 1977, Nature.

[19]  D. A. Smith,et al.  Comparison of anticoccidial efficacy, resistance and tolerance of narasin, monensin and lasalocid in chicken battery trials. , 1977, Poultry science.

[20]  N. Stewart,et al.  Tolerance to imidocarb induced experimentally in tick-transmitted Babesia argentina. , 1977, Australian veterinary journal.

[21]  L. Mcdougald,et al.  Anticoccidial drugs: effects on infectivity and survival intracellularly of Eimeria tenella sporozoites. , 1976, Experimental parasitology.

[22]  R. Fayer,et al.  Effect of monensin on experimental infections of Eimeria ninakohlyakimovae in lambs. , 1976, American journal of veterinary research.

[23]  A. J. Wilson,et al.  Observations on a herd of beef cattle maintained in a tsetse area. II. Assessment of the development of immunity in association with trypanocidal drug treatment. , 1976, Tropical animal health and production.

[24]  A. J. Wilson,et al.  Maintenance of a Herd of Breeding Cattle in an Area of High Trypanosome Challenge , 1975, Tropical Animal Health and Production.

[25]  K. Kuttler.  The effect of Imidocarb treatment on Babesia in the bovine and the tick (Boophilus microplus). , 1975, Research in veterinary science.

[26]  P. L. Long,et al.  Coccidiosis in broilers: evaluation of infection by the examination of broiler house litter for oocysts. , 1975, Avian pathology : journal of the W.V.P.A.

[27]  W. Frerichs,et al.  Treatment of equine piroplasmosis (B caballi) with imidocarb dipropionate , 1974, Veterinary Record.

[28]  M. Mansfield,et al.  Efficacy of monensin against bovine coccidiosis in young Holstein-Friesian calves. , 1973, The Journal of protozoology.

[29]  E. Stebbing.  Britain's National Forests Bedgebury and Cannock Chase , 1952, Nature.