Alteration mineral assemblages are important to the understanding of and exploration for hydrothermal ore deposits. Conventional mapping tools may not identify fine-grained minerals or define important compositional variations. Field portable short-wave infrared (SWIR) spectrometers solve some of these problems and provide a valuable tool for evaluating the distribution of alteration assemblages. Spectrometers such as the PIMA-II allow rapid identification of minerals and mineral-specific variations at a field base. Mineral assemblages, integrated with other exploration data, are then used to target drill holes and guide regional exploration programs. Data collection must be systematically organized and carried out by a trained operator. Analysis of data sets requires the use of spectral reference libraries from different geological environments and may be aided in some cases by computer data processing packages. Integration of results with field observations, petrography, and X-ray diffraction analysis is necessary for complete evaluation. The PIMA (portable infrared mineral analyzer) has been used successfully in the high-sulfidation epithermal, low-sulfidation epithermal, volcanogenic massive sulfide (VMS) and intrusion-related environments. Case studies from these systems demonstrate the ability to rapidly acquire and process SWIR data and produce drill logs and maps. The resulting information is critical for targeting.