Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
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Adam R. Johnson | Jun Liang | J. DeVoss | M. Ultsch | M. Balázs | Lawren C. Wu | C. Eigenbrot | Christine Chang | Birong Zhang | Zhonghua Lin | C. Macleod | Kapil Menghrajani | J. Driscoll | I. Peng | W. Blair | V. Tsui | N. Ghilardi | Anne van Abbema | Kathy Barrett | Leo Berezhkovsky | D. Delarosa | Yingjie Lai | Priscilla Mantik | A. Sambrone | S. Shia | Jan Smith | S. Sohn | Wenqian Yang | P. Bir Kohli | S. Goodacre | Steven Magnuson | Hieu D. Nguyen | Karen Williams | M. Balazs | Pawan Bir Kohli | K. Barrett | Calum Macleod