Recurrent Finkelstein-Seidlmayer Disease in Four First-degree Relatives.

Acute cockade purpura and oedema of young children, also known as Finkelstein-Seidlmayer disease (FSD), is a rare and benign cutaneous small-vessel leukocytoclastic vasculitis syndrome. This condition, which mostly affects the extremities, face and ears, presents with nonpruriginous target-like lesions, often associated with tender, non-pitting oedema (1). It affects children aged 2–60 months in an approximate male-to-female ratio of 2:1, typically does not recur, and often follows a simple febrile illness or an active immunization (1). There are no reports of familial occurrence of FSD. We report here the medical history of a 43-year-old woman and her 3 sons, currently aged 14, 12 and 9 years, who have been affected since birth by frequent and persisting relapses of FSD.