The protective effects of baicalin for respiratory diseases: an update and future perspectives
暂无分享,去创建一个
Meiru Zhao | Xiangyan Li | Zeyu Wang | Qi Wang | Qi Wang | Ziyuan Wang | Ying Wang | Siyu Song | Min Li | Xueyan Li | Siyu Song | Jing Ma | Hongyu Qi | Zeyu Wang | Tian Chen | Guang-ping Liu | L. Ding | Min Li | Jinjin Chen | Ying Wang | Lu Ding | Guangwen Liu | Tian Chen | Meiru Zhao | Hongyu Qi | Jinjin Chen | Ziyuan Wang | Xiangyan Li | Xueyan Li
[1] K. Takeda,et al. Longitudinal analyses and predictive factors of radiation-induced lung toxicity-related parameters after stereotactic radiotherapy for lung cancer , 2022, PloS one.
[2] F. Dahlke,et al. Rationale for Use of Sphingosine-1-Phosphate Receptor Modulators in COVID-19 Patients: Overview of Scientific Evidence , 2022, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[3] D. Glossman-Mitnik,et al. Exploration of Anti-HIV Phytocompounds against SARS-CoV-2 Main Protease: Structure-Based Screening, Molecular Simulation, ADME Analysis and Conceptual DFT Studies , 2022, Molecules.
[4] Kriengsak Lirdprapamongkol,et al. PLGA-Lipid Hybrid Nanoparticles for Overcoming Paclitaxel Tolerance in Anoikis-Resistant Lung Cancer Cells , 2022, Molecules.
[5] Mateusz Kciuk,et al. Computational Bioprospecting Guggulsterone against ADP Ribose Phosphatase of SARS-CoV-2 , 2022, Molecules.
[6] Chunling Xiao,et al. Protective effect and mechanism of baicalin on lung inflammatory injury in BALB/cJ mice induced by PM2.5. , 2022, Ecotoxicology and environmental safety.
[7] S. Uddin,et al. Non-Invasive Biomarkers for Early Lung Cancer Detection , 2022, Cancers.
[8] V. Novakovic,et al. Pathophysiological mechanisms of thrombosis in acute and long COVID-19 , 2022, Frontiers in Immunology.
[9] Fei Ye,et al. Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis , 2022, Frontiers in Pharmacology.
[10] Zhihong Wu,et al. Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway. , 2022, European journal of pharmacology.
[11] Xi-jun Wang,et al. Multi-Omics Approaches in Colorectal Cancer Screening and Diagnosis, Recent Updates and Future Perspectives , 2022, Cancers.
[12] O. Sabzevari,et al. Hybrid Ultrasound-Activated Nanoparticles Based on Graphene Quantum Dots for Cancer Treatment. , 2022, International journal of pharmaceutics.
[13] Jia Hua Cheng,et al. Development of Paeonol Liposomes: Design, Optimization, in vitro and in vivo Evaluation , 2022, International journal of nanomedicine.
[14] D. Zorov,et al. Development of an In Vitro Model of SARS-CoV-Induced Acute Lung Injury for Studying New Therapeutic Approaches , 2022, Antioxidants.
[15] Z. Ye,et al. Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing , 2022, Frontiers in Pharmacology.
[16] G. Floresta,et al. An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022 , 2022, Molecules.
[17] Q. Shi,et al. Baicalin Inhibits Inflammation in Rats with Chronic Obstructive Pulmonary Disease by the TLR2/MYD88/NF-κBp65 Signaling Pathway , 2022, Evidence-based complementary and alternative medicine : eCAM.
[18] A. Pandey,et al. Role of baicalin as a potential therapeutic agent in hepatobiliary and gastrointestinal disorders: A review , 2022, World journal of gastroenterology.
[19] A. Salawi. Self-emulsifying drug delivery systems: a novel approach to deliver drugs , 2022, Drug delivery.
[20] Yun-Man Li,et al. Oxidative Stress and Antioxidative Therapy in Pulmonary Arterial Hypertension , 2022, Molecules.
[21] L. Wollin,et al. BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis , 2022, Frontiers in Pharmacology.
[22] Feng Feng,et al. Baicalin inhibits inflammation of lipopolysaccharide-induced acute lung injury toll like receptor-4/myeloid differentiation primary response 88/nuclear factor-kappa B signaling pathway. , 2022, Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
[23] Weiming Xu,et al. Liver-Targeted Nanoparticles Facilitate the Bioavailability and Anti-HBV Efficacy of Baicalin In Vitro and In Vivo , 2022, Biomedicines.
[24] Jia You,et al. Inspiration for COVID-19 Treatment: Network Analysis and Experimental Validation of Baicalin for Cytokine Storm , 2022, Frontiers in Pharmacology.
[25] Zhan-sheng Hu,et al. Salidroside attenuates HALI via IL-17A-mediated ferroptosis of alveolar epithelial cells by regulating Act1-TRAF6-p38 MAPK pathway , 2022, Cell Communication and Signaling.
[26] Xuan Zhou,et al. Baicalin Inhibits EMT through PDK1/AKT Signaling in Human Nonsmall Cell Lung Cancer , 2021, Journal of oncology.
[27] Ming Yang,et al. Scutellaria baicalensis Extract-phospholipid Complex: Preparation and Initial Pharmacodynamics Research in Rats , 2021, Current pharmaceutical biotechnology.
[28] N. Mohammadtursun,et al. Baicalin ameliorates cigarette smoke-induced airway inflammation in rats by modulating HDAC2/NF-κB/PAI-1 signalling. , 2021, Pulmonary pharmacology & therapeutics.
[29] D. Chen,et al. Baicalein, Baicalin, and Wogonin: Protective Effects against Ischemia-Induced Neurodegeneration in the Brain and Retina , 2021, Oxidative medicine and cellular longevity.
[30] Junguang Jiang,et al. Baicalin alleviates chronic obstructive pulmonary disease through regulation of HSP72-mediated JNK pathway , 2021, Molecular medicine.
[31] S. Sarafianos,et al. Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase , 2021, Microorganisms.
[32] M. Belvisi,et al. Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis , 2021, American journal of respiratory cell and molecular biology.
[33] Shuguang Huang,et al. MNK as a potential pharmacological target for suppressing LPS-induced acute lung injury in mice , 2021, Biochemical Pharmacology.
[34] Haiping Zhao,et al. PBK/TOPK: A Therapeutic Target Worthy of Attention , 2021, Cells.
[35] Shizhang Wei,et al. Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects. , 2021, Pharmacological research.
[36] Wen Jiang,et al. Protective effect of baicalin against pulmonary arterial hypertension vascular remodeling through regulation of TNF‐α signaling pathway , 2021, Pharmacology research & perspectives.
[37] Qinggang Meng,et al. A metabolomic approach to elucidate the inhibitory effects of baicalin in pulmonary fibrosis , 2021, Pharmaceutical biology.
[38] Fucheng Zhao,et al. Baicalin suppresses lung cancer growth phenotypes via miR-340-5p/NET1 axis , 2021, Bioengineered.
[39] Xia Ding,et al. Baicalin Induces Apoptosis and Suppresses the Cell Cycle Progression of Lung Cancer Cells Through Downregulating Akt/mTOR Signaling Pathway , 2021, Frontiers in Molecular Biosciences.
[40] Yanfeng Wang,et al. Hypoxia-Inducible Factor-1: A Potential Target to Treat Acute Lung Injury , 2020, Oxidative medicine and cellular longevity.
[41] Qiyue Yang,et al. Baicalin Liposome Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Inhibiting TLR4/JNK/ERK/NF-κB Pathway , 2020, Mediators of inflammation.
[42] Yi Qu,et al. Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review , 2020, Frontiers in Pharmacology.
[43] F. Zhang,et al. Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms , 2020, Pharmacological Research.
[44] J Zhang,et al. LncRNA-AK149641 associated with airway inflammation in an OVA-induced asthma mouse model , 2020, Journal of Bioenergetics and Biomembranes.
[45] W. Labaki,et al. Chronic Obstructive Pulmonary Disease , 2020, Annals of Internal Medicine.
[46] L. Q. Quintans Júnior,et al. The use of cyclodextrin inclusion complexes to improve anticancer drug profiles: a systematic review , 2020, Expert opinion on drug delivery.
[47] C. Cho,et al. Development and Evaluation of Docetaxel-Phospholipid Complex Loaded Self-Microemulsifying Drug Delivery System: Optimization and In Vitro/Ex Vivo Studies , 2020, Pharmaceutics.
[48] J. Kou,et al. Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation , 2020, Redox biology.
[49] Raju C Reddy,et al. Bidirectional interaction of airway epithelial remodeling and inflammation in asthma. , 2020, Clinical science.
[50] J. Flynn,et al. ACE2 (Angiotensin-Converting Enzyme 2), COVID-19, and ACE Inhibitor and Ang II (Angiotensin II) Receptor Blocker Use During the Pandemic , 2020, Hypertension.
[51] Y. Nishimura,et al. Group 2 Innate Lymphoid Cells and the House Dust Mite-Induced Asthma Mouse Model , 2020, Cells.
[52] Zhenhua Li,et al. Baicalin alleviates bleomycin-induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway , 2020, Molecular medicine reports.
[53] M. Letko,et al. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses , 2020, Nature Microbiology.
[54] Fangdi Hu,et al. The metabolic effect of gut microbiota on drugs , 2020, Drug metabolism reviews.
[55] C. Yuan,et al. Baicalein, an enteric microbial metabolite, suppresses gut inflammation and cancer progression in ApcMin/+ mice , 2019, Clinical and Translational Oncology.
[56] B. King-Kallimanis,et al. US Food and Drug Administration review of statistical analysis of patient-reported outcomes in lung cancer clinical trials approved between January, 2008, and December, 2017. , 2019, The Lancet. Oncology.
[57] Jinxia Wang,et al. Baicalin prevents pulmonary arterial remodeling in vivo via the AKT/ERK/NF-κB signaling pathways , 2019, Pulmonary circulation.
[58] Xiangli Meng,et al. Baicalin ameliorates lipopolysaccharide-induced acute lung injury in mice by suppressing oxidative stress and inflammation via the activation of the Nrf2-mediated HO-1 signaling pathway , 2019, Naunyn-Schmiedeberg's Archives of Pharmacology.
[59] Ji-cheng Tantai,et al. Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7 , 2019, Cell death & disease.
[60] Peng-Fei Yi,et al. Baicalin alleviated APEC-induced acute lung injury in chicken by inhibiting NF-κB pathway activation. , 2019, International immunopharmacology.
[61] Jiahao Huang,et al. Investigating the Phospholipid Effect on the Bioaccessibility of Rosmarinic Acid-Phospholipid Complex through a Dynamic Gastrointestinal in Vitro Model , 2019, Pharmaceutics.
[62] Xin Diao,et al. Baicalin suppresses lung cancer growth by targeting PDZ-binding kinase/T-LAK cell-originated protein kinase , 2019, Bioscience reports.
[63] W. Yao,et al. Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF‐κB signaling pathway , 2019, CNS neuroscience & therapeutics.
[64] X. Hou,et al. Development of dual-targeted nano-dandelion based on an oligomeric hyaluronic acid polymer targeting tumor-associated macrophages for combination therapy of non-small cell lung cancer , 2019, Drug delivery.
[65] In-Soo Yoon,et al. Preparation, Characterization, and In Vivo Evaluation of an Oral Multiple Nanoemulsive System for Co-Delivery of Pemetrexed and Quercetin , 2018, Pharmaceutics.
[66] Wei Zhang,et al. Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosis , 2018, Journal of cellular and molecular medicine.
[67] M. Haider,et al. Thermogelling Platform for Baicalin Delivery for Versatile Biomedical Applications. , 2018, Molecular pharmaceutics.
[68] Jinghua Peng,et al. Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway , 2018, Medical science monitor : international medical journal of experimental and clinical research.
[69] Linghao Qin,et al. Combination of Phospholipid Complex and Submicron Emulsion Techniques for Improving Oral Bioavailability and Therapeutic Efficacy of Water-Insoluble Drug. , 2018, Molecular pharmaceutics.
[70] Hongfei Wu,et al. Formulation optimization and the absorption mechanisms of nanoemulsion in improving baicalin oral exposure , 2018, Drug development and industrial pharmacy.
[71] J. Ryu,et al. Current Concepts in Pathogenesis, Diagnosis, and Management of Smoking‐Related Interstitial Lung Diseases , 2017, Chest.
[72] Bin Zhou,et al. Baicalin potentiates TRAIL‑induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production. , 2017, Molecular medicine reports.
[73] Jinhua Lu,et al. Baicalin alleviates radiation-induced epithelial-mesenchymal transition of primary type II alveolar epithelial cells via TGF-β and ERK/GSK3β signaling pathways. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[74] Xuemei Zhang,et al. Regulatory effect of baicalin on the imbalance of Th17/Treg responses in mice with allergic asthma. , 2017, Journal of ethnopharmacology.
[75] Liangxing Wang,et al. Baicalin attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2A receptor-induced SDF-1/CXCR4/PI3K/AKT signaling , 2017, Journal of Biomedical Science.
[76] R. Sharif. Overview of idiopathic pulmonary fibrosis (IPF) and evidence-based guidelines. , 2017, The American journal of managed care.
[77] P. Deng,et al. The formation of a host‐guest inclusion complex system between β‐cyclodextrin and baicalin and its dissolution characteristics , 2017, The Journal of pharmacy and pharmacology.
[78] H. Walczak,et al. Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy , 2017, Nature Reviews Cancer.
[79] I. Adcock,et al. Animal models of COPD: What do they tell us? , 2017, Respirology.
[80] Yonggen Zou,et al. Lung-targeting drug delivery system of baicalin-loaded nanoliposomes: development, biodistribution in rabbits, and pharmacodynamics in nude mice bearing orthotopic human lung cancer , 2016, International journal of nanomedicine.
[81] Zhi-wei Xu,et al. Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt. , 2017, International journal of oncology.
[82] F. Liu,et al. Baicalin attenuates inflammation in mice with OVA-induced asthma by inhibiting NF-κB and suppressing CCR7/CCL19/CCL21. , 2016, International journal of molecular medicine.
[83] Jie Song,et al. Characterization and Bioavailability Study of Baicalin-mesoporous Carbon Nanopowder Solid Dispersion , 2016, Pharmacognosy magazine.
[84] Yicheng He,et al. Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-induced ERK1/2 signaling pathway , 2016, BMC Pulmonary Medicine.
[85] Liangxing Wang,et al. Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9 , 2016, Evidence-based complementary and alternative medicine : eCAM.
[86] L. Minh,et al. Baicalin loaded in folate-PEG modified liposomes for enhanced stability and tumor targeting. , 2016, Colloids and surfaces. B, Biointerfaces.
[87] Yonggen Zou,et al. LC-UV Determination of Baicalin in Rabbit Plasma and Tissues for Application in Pharmacokinetics and Tissue Distribution Studies of Baicalin after Intravenous Administration of Liposomal and Injectable Formulations , 2016, Molecules.
[88] Yongmun Choi,et al. Identification and Characterization of Baicalin as a Phosphodiesterase 4 Inhibitor , 2016, Phytotherapy research : PTR.
[89] G. Zhai,et al. In vitro and in vivo study of Baicalin-loaded mixed micelles for oral delivery , 2015, Drug delivery.
[90] D. Weng,et al. Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting the Th17 Response in C57BL/6 Mice. , 2015, Journal of natural products.
[91] Y. Park,et al. Baseline Characteristics of the Korean Registry of Pulmonary Arterial Hypertension , 2015, Journal of Korean medical science.
[92] Jiyang Xu,et al. Baicalin attenuates angiotensin II-induced endothelial dysfunction. , 2015, Biochemical and biophysical research communications.
[93] N. Wheate,et al. The state-of-play and future of platinum drugs. , 2015, Endocrine-related cancer.
[94] S. Chao,et al. Therapeutic effects of baicalin on monocrotaline-induced pulmonary arterial hypertension by inhibiting inflammatory response. , 2015, International immunopharmacology.
[95] Yanjiang Qiao,et al. Profiling and identification of the metabolites of baicalin and study on their tissue distribution in rats by ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer. , 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[96] Q. Hamid,et al. Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD , 2014, Respiratory Research.
[97] J. Olin,et al. Asthma: pathogenesis and novel drugs for treatment , 2014, BMJ : British Medical Journal.
[98] G. Zhai,et al. Preparation, optimization, characterization and cytotoxicity in vitro of Baicalin-loaded mixed micelles. , 2014, Journal of colloid and interface science.
[99] Jun Wu,et al. Preparation, pharmacokinetics and biodistribution of baicalin-loaded liposomes , 2014, International journal of nanomedicine.
[100] B. Liu,et al. Downregulation of miR‐638 promotes invasion and proliferation by regulating SOX2 and induces EMT in NSCLC , 2014, FEBS letters.
[101] Xiaoling Li,et al. Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin , 2014, Acta pharmaceutica Sinica. B.
[102] P. Barnes. Cellular and molecular mechanisms of chronic obstructive pulmonary disease. , 2014, Clinics in chest medicine.
[103] T. Allen,et al. Interleukin 8 and acute lung injury. , 2014, Archives of pathology & laboratory medicine.
[104] Shiping Ma,et al. Anti‐asthmatic Effects of Baicalin in a Mouse Model of Allergic Asthma , 2014, Phytotherapy research : PTR.
[105] Bo-wen Wang,et al. Dissolution and pharmacokinetics of baicalin–polyvinylpyrrolidone coprecipitate , 2013, The Journal of pharmacy and pharmacology.
[106] Hong Shen,et al. PBK/TOPK expression in non‐small‐cell lung cancer: its correlation and prognostic significance with Ki67 and p53 expression , 2013, Histopathology.
[107] Junjiang Fu,et al. Nanoemulsion improves the oral bioavailability of baicalin in rats: in vitro and in vivo evaluation , 2013, International journal of nanomedicine.
[108] Hongtao Zhao,et al. Biotransformation of baicalin to baicalein significantly strengthens the inhibition potential towards UDP-glucuronosyltransferases (UGTs) isoforms. , 2013, Die Pharmazie.
[109] Weifeng Zhu,et al. Process optimization and evaluation of novel baicalin solid nanocrystals , 2013, International journal of nanomedicine.
[110] M. Hattori,et al. Baicalein 6-O-β-D-glucopyranuronoside is a main metabolite in the plasma after oral administration of baicalin, a flavone glucuronide of scutellariae radix, to rats. , 2013, Biological & pharmaceutical bulletin.
[111] Q. Luo,et al. Effects of Baicalin on Airway Remodeling in Asthmatic Mice , 2013, Planta Medica.
[112] Moisés Selman,et al. Idiopathic pulmonary fibrosis , 2011, The Lancet.
[113] Baojun Liu,et al. Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models. , 2010, Pulmonary pharmacology & therapeutics.
[114] Xiaofei Shang,et al. The genus Scutellaria an ethnopharmacological and phytochemical review. , 2010, Journal of ethnopharmacology.
[115] M. Lehner,et al. PDE4 inhibitors: a review of current developments (2005 – 2009) , 2009, Expert opinion on therapeutic patents.
[116] Jianbin Chao,et al. Preparation and characterization of the inclusion complex of Baicalin (BG) with beta-CD and HP-beta-CD in solution: an antioxidant ability study. , 2009, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
[117] Shu-Yu Wu,et al. Baicalin attenuates air embolism‐induced acute lung injury in rat isolated lungs , 2009, British journal of pharmacology.
[118] B. Sarmento,et al. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. , 2007, Drug discovery today.
[119] Anindya Dutta,et al. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. , 2007, Genes & development.
[120] Guangji Wang,et al. Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. , 2007, Journal of ethnopharmacology.
[121] N. Venkatesan,et al. Protection from acute and chronic lung diseases by curcumin. , 2007, Advances in experimental medicine and biology.
[122] Z. Zuo,et al. Involvement of UDP-Glucuronosyltransferases in the Extensive Liver and Intestinal First-Pass Metabolism of Flavonoid Baicalein , 2006, Pharmaceutical Research.
[123] Li Taiming,et al. Investigation of the absorption mechanisms of baicalin and baicalein in rats. , 2006, Journal of pharmaceutical sciences.
[124] Marie-Hélène Dufresne,et al. Block copolymer micelles: preparation, characterization and application in drug delivery. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[125] J. Xing,et al. Absorption and enterohepatic circulation of baicalin in rats. , 2005, Life sciences.
[126] S. Lowe,et al. A microRNA polycistron as a potential human oncogene , 2005, Nature.
[127] Z. Siddik,et al. Cisplatin: mode of cytotoxic action and molecular basis of resistance , 2003, Oncogene.
[128] M. Ishihara,et al. [Combination use of kampo-medicines and drugs affecting intestinal bacterial flora]. , 2002, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
[129] K. Kobashi,et al. Balicalin, the Predominant Flavone Glucuronide of Scutellariae Radix, is Absorbed from the Rat Gastrointestinal Tract as the Aglycone and Restored to its Original Form , 2000, The Journal of pharmacy and pharmacology.