Analysis of cellular responses to aflatoxin B(1) in yeast expressing human cytochrome P450 1A2 using cDNA microarrays.

[1]  L. Breeden,et al.  Expression of a Human Cytochrome P450 in Yeast Permits Analysis of Pathways for Response to and Repair of Aflatoxin-Induced DNA Damage , 2005, Molecular and Cellular Biology.

[2]  U. Certa,et al.  Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1. , 2004, Molecular biology of the cell.

[3]  C. Lengauer,et al.  hCDC4 and genetic instability in cancer. , 2004 .

[4]  Wiguins Etienne,et al.  Comparison of mRNA gene expression by RT-PCR and DNA microarray. , 2004, BioTechniques.

[5]  M. O’Reilly,et al.  DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway , 2004, The EMBO journal.

[6]  Zhaohui S. Qin,et al.  Statistical resynchronization and Bayesian detection of periodically expressed genes. , 2004, Nucleic acids research.

[7]  A. Gunjan,et al.  A Rad53 Kinase-Dependent Surveillance Mechanism that Regulates Histone Protein Levels in S. cerevisiae , 2003, Cell.

[8]  P. Bushel,et al.  ATM-Dependent and -Independent Gene Expression Changes in Response to Oxidative Stress, Gamma Irradiation, and UV Irradiation , 2003, Radiation research.

[9]  Lue Ping Zhao,et al.  Array rank order regression analysis for the detection of gene copy-number changes in human cancer. , 2003, Genomics.

[10]  Roger E Bumgarner,et al.  The Transcriptome and Its Translation during Recovery from Cell Cycle Arrest in Saccharomyces cerevisiae* , 2003, Molecular & Cellular Proteomics.

[11]  John Quackenbush Microarray data normalization and transformation , 2002, Nature Genetics.

[12]  L. Breeden,et al.  Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. , 2002, Genes & development.

[13]  G. Churchill Fundamentals of experimental design for cDNA microarrays , 2002, Nature Genetics.

[14]  J. Olson,et al.  A regression-based method to identify differentially expressed genes in microarray time course studies and its application in an inducible Huntington's disease transgenic model. , 2002, Human molecular genetics.

[15]  E. Cacci,et al.  Impairment of cell cycle progression by aflatoxin B1 in human cell lines. , 2002, Mutagenesis.

[16]  M. Dutreix,et al.  Transcriptional induction of repair genes during slowing of replication in irradiated Saccharomyces cerevisiae. , 2001, Mutation research.

[17]  Roger Brent,et al.  Yeast Cbk1 and Mob2 Activate Daughter-Specific Genetic Programs to Induce Asymmetric Cell Fates , 2001, Cell.

[18]  D. Botstein,et al.  Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. , 2001, Molecular biology of the cell.

[19]  C. Kooperberg,et al.  Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression , 2001, Molecular and Cellular Biology.

[20]  J. Thomas,et al.  An efficient and robust statistical modeling approach to discover differentially expressed genes using genomic expression profiles. , 2001, Genome research.

[21]  L. P. Zhao,et al.  Statistical modeling of large microarray data sets to identify stimulus-response profiles , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[22]  E. Lander,et al.  Remodeling of yeast genome expression in response to environmental changes. , 2001, Molecular biology of the cell.

[23]  D. Botstein,et al.  Genomic expression programs in the response of yeast cells to environmental changes. , 2000, Molecular biology of the cell.

[24]  S. Elledge,et al.  The DNA damage response: putting checkpoints in perspective , 2000, Nature.

[25]  George M. Church,et al.  Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes , 2000, Molecular and Cellular Biology.

[26]  S. Elledge,et al.  The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit , 2000, Current Biology.

[27]  J. Groopman,et al.  DNA damage by mycotoxins. , 1999, Mutation research.

[28]  L. Samson,et al.  Global response of Saccharomyces cerevisiae to an alkylating agent. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Michael Ruogu Zhang,et al.  Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. , 1998, Molecular biology of the cell.

[30]  L. Breeden,et al.  Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae. , 1997, Genes & development.

[31]  Stephen J. Elledge,et al.  Cell Cycle Checkpoints: Preventing an Identity Crisis , 1996, Science.

[32]  E. Gallagher,et al.  The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4. , 1996, Toxicology and applied pharmacology.

[33]  C. Sengstag,et al.  Genotoxicity of aflatoxin B1: evidence for a recombination-mediated mechanism in Saccharomyces cerevisiae. , 1996, Cancer research.

[34]  L. Hartwell,et al.  A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage , 1995, Cell.

[35]  C. Sengstag,et al.  DNA recombination induced by aflatoxin B1 activated by cytochrome P450 1A enzymes , 1994, Molecular carcinogenesis.

[36]  M. Mendenhall,et al.  An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells. , 1994, Molecular and cellular biology.

[37]  C. Sengstag,et al.  Saccharomyces cerevisiae: an alternative source for human microsomal liver enzymes and its use in drug interaction studies. , 1993, Toxicology.

[38]  R. A. Metcalf,et al.  Mutational hot spot in the p53 gene in human hepatocellular carcinomas , 1991, Nature.

[39]  Y. Hochberg A sharper Bonferroni procedure for multiple tests of significance , 1988 .

[40]  M. Osley,et al.  Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes , 1987, Molecular and cellular biology.

[41]  J. Miller,et al.  Base substitution mutations induced by metabolically activated aflatoxin B1. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[42]  J. Smyth,et al.  Progress in Clinical and Biological Research , 1979 .

[43]  R. C. Garner,et al.  Aflatoxin B-oxide generated by chemical or enzymic oxidation of aflatoxin B1 causes guanine substitution in nucleic acids , 1977, Nature.

[44]  B. Ames,et al.  Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[45]  E. Friedberg,et al.  DNA Repair and Mutagenesis , 2006 .

[46]  D. Eaton,et al.  Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[47]  D. Botstein,et al.  Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. , 2000, Cold Spring Harbor symposia on quantitative biology.

[48]  M. Santoro,et al.  Heat shock factors and the control of the stress response. , 2000, Biochemical pharmacology.

[49]  E. Gallagher,et al.  Mechanisms of aflatoxin carcinogenesis. , 1994, Annual review of pharmacology and toxicology.

[50]  A. Hall,et al.  11 – Epidemiology of Aflatoxin-Related Disease , 1993 .

[51]  John Davis Groopman,et al.  The toxicology of aflatoxins: human health, veterinary and agricultural significance. , 1993 .

[52]  S. Dorland,et al.  Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. , 1992, Genes & development.

[53]  M. Osley The regulation of histone synthesis in the cell cycle. , 1991, Annual review of biochemistry.

[54]  J. Essigmann,et al.  The role of carcinogen DNA adduct structure in the induction of mutations. , 1990, Progress in clinical and biological research.

[55]  H. Neumann,et al.  Differences in aflatoxin B1-susceptibility of rat and mouse are correlated with the capability in vitro to inactivate aflatoxin B1-epoxide. , 1981, Carcinogenesis.