Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation

[1]  T. Speed,et al.  A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development , 2021, Cell.

[2]  Yigong Shi,et al.  Structure of the activated human minor spliceosome , 2021, Science.

[3]  G. Azhar,et al.  Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function , 2021, International journal of molecular sciences.

[4]  G. Georg,et al.  Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception† , 2020, Biology of Reproduction.

[5]  H. Ohta,et al.  ZGLP1 is a determinant for the oogenic fate in mice , 2020, Science.

[6]  F. Tang,et al.  Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks , 2020, Cell Research.

[7]  M. Ko,et al.  MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. , 2020, Developmental cell.

[8]  Jiang Liu,et al.  The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair , 2019 .

[9]  J. Baker,et al.  Gene expression across mammalian organ development , 2019, Nature.

[10]  F. Fuller-Pace,et al.  DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia , 2019, Nature Communications.

[11]  R. Xavier,et al.  Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice , 2019, PLoS genetics.

[12]  J. Grenier,et al.  CDK2 kinase activity is a regulator of male germ cell fate , 2019, Development.

[13]  U. Schmitz,et al.  Intron retention enhances gene regulatory complexity in vertebrates , 2017, Genome Biology.

[14]  K. Nakayama,et al.  Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells , 2017, Development.

[15]  Xuerui Yang,et al.  Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis , 2017, Cell Research.

[16]  Xiu-Jie Wang,et al.  Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation , 2017, Cell Research.

[17]  F. Baralle,et al.  Alternative splicing as a regulator of development and tissue identity , 2017, Nature Reviews Molecular Cell Biology.

[18]  Weiren Huang,et al.  A nonsense mutation in Ccdc62 gene is responsible for spermiogenesis defects and male infertility in repro29/repro29 mice† , 2017, Biology of Reproduction.

[19]  Qianhua Xu,et al.  BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis , 2017, Nature Communications.

[20]  Kun Zhang,et al.  The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. , 2016, Cell reports.

[21]  M. Swanson,et al.  RNA mis-splicing in disease , 2015, Nature Reviews Genetics.

[22]  Molly M. Hannigan,et al.  RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development , 2015, Molecular and Cellular Biology.

[23]  Sarah J. Kurley,et al.  The spliceosome is a therapeutic vulnerability in MYC-driven cancer , 2015, Nature.

[24]  Lan Lin,et al.  rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data , 2014, Proceedings of the National Academy of Sciences.

[25]  M. Wilkinson,et al.  Transcriptional control of spermatogonial maintenance and differentiation. , 2014, Seminars in cell & developmental biology.

[26]  Åsa K. Björklund,et al.  Full-length RNA-seq from single cells using Smart-seq2 , 2014, Nature Protocols.

[27]  M. Kanatsu-Shinohara,et al.  Spermatogonial stem cell self-renewal and development. , 2013, Annual review of cell and developmental biology.

[28]  R. Dixon,et al.  The splicing landscape is globally reprogrammed during male meiosis , 2013, Nucleic acids research.

[29]  D. Zack,et al.  Alternative splicing and retinal degeneration , 2013, Clinical genetics.

[30]  J. Wilce,et al.  RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility , 2013, PLoS genetics.

[31]  D. Duelli,et al.  Targeting RNA splicing for disease therapy , 2013, Wiley interdisciplinary reviews. RNA.

[32]  Debjani Saha,et al.  Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression. , 2012, Biochemical and biophysical research communications.

[33]  M. Gori,et al.  SOHLH1 and SOHLH2 control Kit expression during postnatal male germ cell development , 2012, Journal of Cell Science.

[34]  Philip Machanick,et al.  MEME-ChIP: motif analysis of large DNA datasets , 2011, Bioinform..

[35]  M. Griswold,et al.  The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells. , 2010, Developmental cell.

[36]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[37]  M. Griswold,et al.  The key role of vitamin A in spermatogenesis. , 2010, The Journal of clinical investigation.

[38]  D. Auboeuf,et al.  Splicing factor and exon profiling across human tissues , 2010, Nucleic acids research.

[39]  S. Krawetz,et al.  Molecular aspects of male fertility , 2009, EMBO reports.

[40]  Yumiko Saga,et al.  The RNA-Binding Protein NANOS2 Is Required to Maintain Murine Spermatogonial Stem Cells , 2009, Science.

[41]  D. Page,et al.  Germ Cell-Intrinsic and -Extrinsic Factors Govern Meiotic Initiation in Mouse Embryos , 2008, Science.

[42]  R. Brinster,et al.  Regulation of spermatogonial stem cell self-renewal in mammals. , 2008, Annual review of cell and developmental biology.

[43]  David C Page,et al.  Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice , 2008, Proceedings of the National Academy of Sciences.

[44]  Y. Saga,et al.  Nanos2 suppresses meiosis and promotes male germ cell differentiation. , 2008, Genes & development.

[45]  G. Draetta,et al.  Characterization of the BUD31 gene of Saccharomyces cerevisiae. , 2004, Biochemical and biophysical research communications.

[46]  P. Pandolfi,et al.  Essential role of Plzf in maintenance of spermatogonial stem cells , 2004, Nature Genetics.

[47]  P. Sassone-Corsi,et al.  Temporal Association of Protamine 1 with the Inner Nuclear Membrane Protein Lamin B Receptor during Spermiogenesis* , 2004, Journal of Biological Chemistry.

[48]  P. Kaldis,et al.  Cdk2 Knockout Mice Are Viable , 2003, Current Biology.

[49]  Pierre Dubus,et al.  Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice , 2003, Nature Genetics.

[50]  Yali Chen,et al.  Generation and in Vitro Differentiation of a Spermatogonial Cell Line , 2002, Science.

[51]  T. Kwon,et al.  The Differential Catalytic Activity of Alternatively Spliced cdk2α and cdk2β in the G1/S Transition and Early S Phase , 1998 .

[52]  Simone Picelli,et al.  Full-Length Single-Cell RNA Sequencing with Smart-seq2. , 2019, Methods in molecular biology.

[53]  Hyuk Song,et al.  The KIT is a putative marker for differentiating spermatogonia in stallions. , 2015, Animal reproduction science.

[54]  S. Salzberg,et al.  Thousands of exon skipping events differentiate among splicing patterns in sixteen human tissues [v1; ref status: indexed, http://f1000r.es/1p0] , 2013 .

[55]  Yue Li.  RIPSeeker : a statistical package for identifying protein-associated transcripts from RIP-seq experiments , 2013 .

[56]  Y. H. Kim,et al.  The differential catalytic activity of alternatively spliced cdk2 alpha and cdk2 beta in the G1/S transition and early S phase. , 1998, Experimental cell research.