A potential decline in life expectancy in the United States in the 21st century.

Forecasts of life expectancy are an important component of public policy that influence age-based entitlement programs such as Social Security and Medicare. Although the Social Security Administration recently raised its estimates of how long Americans are going to live in the 21st century, current trends in obesity in the United States suggest that these estimates may not be accurate. From our analysis of the effect of obesity on longevity, we conclude that the steady rise in life expectancy during the past two centuries may soon come to an end.

[1]  W. R. Macdonell.  ON THE EXPECTATION OF LIFE IN ANCIENT ROME, AND IN THE PROVINCES OF HISPANIA AND LUSITANIA, AND AFRICA. , 1913 .

[2]  Elsie Blumberg,et al.  The Institutional Care of Children. United Nations Department of Economic and Social Affairs , 1957 .

[3]  Bayo Fr,et al.  United States population projections for OASDI cost estimates 1980 , 1978 .

[4]  J. Tobin,et al.  Impact of age on weight goals. , 1985, Annals of internal medicine.

[5]  Wade Ah,et al.  Social Security area population projections: 1987. , 1988 .

[6]  N. Woodford,et al.  VANCOMYCIN-RESISTANT ENTEROCOCCI , 1988, The Lancet.

[7]  N. Dubrawsky.  Cancer statistics , 1989, CA: a cancer journal for clinicians.

[8]  C. Cassel,et al.  In search of Methuselah: estimating the upper limits to human longevity. , 1990, Science.

[9]  W. Dietz,et al.  Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1935. , 1992, The New England journal of medicine.

[10]  McGinnis Jm,et al.  Actual causes of death in the United States. , 1993 .

[11]  N Woodford,et al.  Vancomycin-resistant enterococci , 1993, The Lancet.

[12]  P. Blackman.  Actual causes of death in the United States. , 1994, JAMA.

[13]  Prospect for extended survival: a critical review of the biological evidence. , 1996 .

[14]  S. Olshansky,et al.  Infectious diseases -- new and ancient threats to world health. , 1997, Population bulletin.

[15]  F. Tenover,et al.  Vancomycin-resistant enterococci outside the health-care setting: prevalence, sources, and public health implications. , 1997, Emerging infectious diseases.

[16]  M. Feldman,et al.  Gene-Culture Coevolution and Sex Ratios: II. Sex-Chromosomal Distorters and Cultural Preferences for Offspring Sex , 1997, Theoretical Population Biology.

[17]  V. Kannisto.  Health and Mortality Among Elderly Populations , 1998 .

[18]  G A Colditz,et al.  Current estimates of the economic cost of obesity in the United States. , 1998, Obesity research.

[19]  M. Thun,et al.  Body-mass index and mortality in a prospective cohort of U.S. adults. , 1999, The New England journal of medicine.

[20]  G. Colditz,et al.  The disease burden associated with overweight and obesity. , 1999, JAMA.

[21]  R. Pinner,et al.  Trends in infectious disease mortality in the United States during the 20th century. , 1999, JAMA.

[22]  Laura A. Conn,et al.  Trends in Infectious Disease Mortality in the United States During the 20th Century , 1999 .

[23]  R. F. S. C. G. J. D. N. C. Worsham,et al.  Decline in deaths from heart disease and stroke--United States, 1900-1999. , 1999, MMWR. Morbidity and mortality weekly report.

[24]  K. Narayan,et al.  The direct health care costs of obesity in the United States. , 1999, American journal of public health.

[25]  J. Manson,et al.  Annual deaths attributable to obesity in the United States. , 1999, JAMA.

[26]  K. Jöckel,et al.  Effect of age on excess mortality in obesity. , 1999, JAMA.

[27]  J. Wilmoth,et al.  Increase of maximum life-span in Sweden, 1861-1999. , 2000, Science.

[28]  Nan Li,et al.  A universal pattern of mortality decline in the G7 countries , 2000, Nature.

[29]  L S Geiss,et al.  Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. , 2000, The Journal of pediatrics.

[30]  Michael M. Engelgau,et al.  Type 2 diabetes among North adolescents: An epidemiologic health perspective , 2000 .

[31]  Teven,et al.  MORTALITY FROM CORONARY HEART DISEASE IN SUBJECTS WITH TYPE 2 DIABETES AND IN NONDIABETIC SUBJECTS WITH AND WITHOUT PRIOR MYOCARDIAL INFARCTION , 2000 .

[32]  R. Steketee,et al.  HIV in the United States at the turn of the century: an epidemic in transition. , 2001, American journal of public health.

[33]  C B Ebbeling,et al.  Type 2 diabetes mellitus in children: primary care and public health considerations. , 2001, JAMA.

[34]  S. Jay Olshansky,et al.  Prospects for Human Longevity , 2001, Science.

[35]  F Vinicor,et al.  The continuing epidemics of obesity and diabetes in the United States. , 2001, JAMA.

[36]  H. Pollack,et al.  Epidemic increase in childhood overweight, 1986-1998. , 2001, JAMA.

[37]  B. Ames,et al.  Time to Talk SENS: Critiquing the Immutability of Human Aging , 2002, Annals of the New York Academy of Sciences.

[38]  Katherine M Flegal,et al.  Prevalence and trends in overweight among US children and adolescents, 1999-2000. , 2002, JAMA.

[39]  C. Ebbeling,et al.  Childhood obesity: public-health crisis, common sense cure , 2002, The Lancet.

[40]  S. Goodwin,et al.  The Practical Guide to the Identification, Evaluation and Treatment of Overweight and Obesity in Adults , 2002 .

[41]  Felicitie C. Bell,et al.  Life Tables for the United States Social Security Area 1900-2100 , 2002 .

[42]  S. Heymsfield,et al.  Establishing body composition in obesity , 2002, Journal of endocrinological investigation.

[43]  J. Vaupel,et al.  Broken Limits to Life Expectancy , 2002, Science.

[44]  E. Arias,et al.  United States life tables, 2000. , 2002, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[45]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2000. , 2002, JAMA.

[46]  Kiang Liu,et al.  Cardiorespiratory fitness in young adulthood and the development of cardiovascular disease risk factors. , 2003, JAMA.

[47]  K. Chapin,et al.  Epidemiology and Outcome of Nosocomial and Community-Onset Bloodstream Infection , 2003, Journal of Clinical Microbiology.

[48]  J. Barendregt,et al.  Methods of estimating years of life lost due to obesity. , 2003, JAMA.

[49]  Marin H Kollef,et al.  The influence of infection on hospital mortality for patients requiring > 48 h of intensive care. , 2003, Chest.

[50]  D. Allison,et al.  Years of life lost due to obesity. , 2003, JAMA.

[51]  A. Jemal,et al.  Cancer Statistics, 2004 , 2004, CA: a cancer journal for clinicians.

[52]  Jay Bhattacharya,et al.  Are the young becoming more disabled? , 2004, Health affairs.

[53]  A. Dyer,et al.  Relation of body mass index in young adulthood and middle age to Medicare expenditures in older age. , 2004, JAMA.

[54]  D. Manuel,et al.  Health-related quality of life and health-adjusted life expectancy of people with diabetes in Ontario, Canada, 1996-1997. , 2004, Diabetes care.

[55]  J. Gerberding,et al.  Actual causes of death in the United States, 2000. , 2004, JAMA.

[56]  D. Willcox,et al.  The Effects of Post-War Dietary Change on Longevity and Health in Okinawa , 2004 .

[57]  Jeffrey B. Schwimmer,et al.  Preventing Childhood Obesity: Health in the Balance , 2005, Environmental Health Perspectives.

[58]  R. May,et al.  Plagues and peoples , 2006, IUBMB life.