Relationship Between Genetic Polymorphisms in Cell Cycle Regulatory Gene TP53 and Polycystic Ovarian Syndrome: A Case–Control Study and In Silico Analyses

[1]  Xinbin Chen,et al.  Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway , 2022, Oncogene.

[2]  Lihong Tan,et al.  MALAT1 downregulation is associated with polycystic ovary syndrome via binding with MDM2 and repressing P53 degradation , 2021, Molecular and Cellular Endocrinology.

[3]  OUP accepted manuscript , 2022, Human Reproduction.

[4]  L. Linares,et al.  The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes , 2021, Nature Communications.

[5]  Yi Luan,et al.  The Role of Mutant p63 in Female Fertility , 2021, International journal of molecular sciences.

[6]  Yuan Zhang,et al.  Arginine Methyltransferase PRMT1 Regulates p53 Activity in Breast Cancer , 2021, Life.

[7]  E. Kremmer,et al.  PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis , 2021, The EMBO journal.

[8]  Jill A. Madden,et al.  Effect of the p53 P72R Polymorphism on Mutant TP53 Allele Selection in Human Cancer. , 2021, Journal of the National Cancer Institute.

[9]  M. Khazaei,et al.  Synergic effect of bee pollen and metformin on proliferation and apoptosis of granulosa cells: Rat model of polycystic ovary syndrome. , 2021, Journal of food biochemistry.

[10]  Sushi Jiang,et al.  LNK promotes granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated AKT-FOXO3 pathway , 2021, Aging.

[11]  Jian Chen,et al.  External fixator combined with three different fixation methods of fibula for treatment of extra-articular open fractures of distal tibia and fibula: a retrospective study , 2020, BMC Musculoskeletal Disorders.

[12]  M. Ghasemi,et al.  An association study of polymorphisms in the H19 imprinted gene in an Iranian population with the risk of polycystic ovary syndrome , 2020, Biology of Reproduction.

[13]  M. Urbanek,et al.  Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis , 2020, PLoS medicine.

[14]  Min Wu,et al.  Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects , 2020, Signal Transduction and Targeted Therapy.

[15]  T. Miyano,et al.  Interaction between growing oocytes and granulosa cells in vitro , 2019, Reproductive medicine and biology.

[16]  A. Mills,et al.  The potential impact of tumor suppressor genes on human gametogenesis: a case-control study , 2019, Journal of Assisted Reproduction and Genetics.

[17]  C. Genestie,et al.  Aberrant granulosa cell-fate related to inactivated p53/Rb signaling contributes to granulosa cell tumors and to FOXL2 downregulation in the mouse ovary , 2019, Oncogene.

[18]  M. Hosseinzadeh‐Attar,et al.  Effects of Selenium Supplementation on Asymmetric Dimethylarginine and Cardiometabolic Risk Factors in Patients with Polycystic Ovary Syndrome , 2019, Biological Trace Element Research.

[19]  A. Dang,et al.  Single nucleotide polymorphisms in treatment of polycystic ovary syndrome: a systematic review , 2019, Drug metabolism reviews.

[20]  Rozeena Shaikh,et al.  Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article , 2019, European journal of obstetrics & gynecology and reproductive biology: X.

[21]  Esra Ermis,et al.  The role of GNLY gene polymorphisms in psoriasis pathogenesis , 2019, Anais brasileiros de dermatologia.

[22]  R. Saravani,et al.  Association study of SREBF-2 gene polymorphisms and the risk of type 2 diabetes in a sample of Iranian population. , 2018, Gene.

[23]  S. Shivaji,et al.  Influence of tumour suppressor gene (TP53, BRCA1 and BRCA2) polymorphisms on polycystic ovary syndrome in South Indian women. , 2018, European journal of obstetrics, gynecology, and reproductive biology.

[24]  B. Wiweko,et al.  The correlation between serum AMH and HOMA-IR among PCOS phenotypes , 2018, BMC Research Notes.

[25]  Z. Rosenwaks,et al.  p53 and reproduction. , 2018, Fertility and sterility.

[26]  Yu Yang,et al.  ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats , 2017, Cell Death and Disease.

[27]  S. Fu,et al.  Akt-mTOR Signaling Mediates Abnormalities in the Proliferation and Apoptosis of Ovarian Granulosa Cells in Patients with Polycystic Ovary Syndrome , 2017, Gynecologic and Obstetric Investigation.

[28]  G. Delitala,et al.  Polycystic ovary syndrome, adipose tissue and metabolic syndrome , 2017, Archives of Gynecology and Obstetrics.

[29]  M. Thangavelu,et al.  Single-nucleotide polymorphism of INS, INSR, IRS1, IRS2, PPAR-G and CAPN10 genes in the pathogenesis of polycystic ovary syndrome , 2017, Journal of Genetics.

[30]  M. Cesari,et al.  Sarcopenia: an overview , 2017, Aging Clinical and Experimental Research.

[31]  L. De Cecco,et al.  A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation , 2016, Cell Death & Disease.

[32]  Dmitriy Sonkin,et al.  TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data , 2016, Human mutation.

[33]  D. Ehrmann,et al.  The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. , 2016, Endocrine reviews.

[34]  F. Petraglia,et al.  Genetic, hormonal and metabolic aspects of PCOS: an update , 2016, Reproductive Biology and Endocrinology.

[35]  V. Naik,et al.  Tumor suppressor genes in oral cancer , 2015 .

[36]  K. Oktay,et al.  BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging1 , 2015, Biology of reproduction.

[37]  A. Velez,et al.  Tumor-suppressor Genes, Cell Cycle Regulatory Checkpoints, and the Skin , 2015, North American journal of medical sciences.

[38]  F. Azizi,et al.  Of PCOS Symptoms, Hirsutism Has the Most Significant Impact on the Quality of Life of Iranian Women , 2015, PloS one.

[39]  Liewei Wang,et al.  DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability , 2015, Cell reports.

[40]  M. Urbanek,et al.  Genetics of the polycystic ovary syndrome , 2013, Molecular and Cellular Endocrinology.

[41]  Ji Ann Jung,et al.  Serum asymmetric dimethylarginine, apelin, and tumor necrosis factor-α levels in non-obese women with polycystic ovary syndrome , 2012, Steroids.

[42]  K. Brusgaard,et al.  Association of polycystic ovary syndrome susceptibility single nucleotide polymorphism rs2479106 and PCOS in Caucasian patients with PCOS or hirsutism as referral diagnosis. , 2012, European journal of obstetrics, gynecology, and reproductive biology.

[43]  A. Khabir,et al.  Haplotype analysis of p53 polymorphisms: Arg72Pro, Ins16bp and G13964C in Tunisian patients with familial or sporadic breast cancer. , 2010, Cancer epidemiology.

[44]  A. Levine,et al.  Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. , 2009, American journal of human genetics.

[45]  Paul D. P. Pharoah,et al.  p53 polymorphisms: cancer implications , 2009, Nature Reviews Cancer.

[46]  Tsuyoshi Saito,et al.  The contributions of resistin and adiponectin gene single nucleotide polymorphisms to the genetic risk for polycystic ovary syndrome in a Japanese population , 2009, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

[47]  Jong-Young Lee,et al.  A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. , 2008, Fertility and sterility.

[48]  A. Storey,et al.  Granulosa cell survival and proliferation are altered in polycystic ovary syndrome. , 2008, The Journal of clinical endocrinology and metabolism.

[49]  L. Giudice,et al.  Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene. , 2008, The Journal of clinical endocrinology and metabolism.

[50]  I. Hwang,et al.  Dual priming oligonucleotide system for the multiplex detection of respiratory viruses and SNP genotyping of CYP2C19 gene , 2007, Nucleic acids research.

[51]  I. Narita,et al.  SAA1 gene polymorphisms and the risk of AA amyloidosis in Japanese patients with rheumatoid arthritis , 2006, Modern rheumatology.

[52]  M. McCarthy,et al.  Obesity and polycystic ovary syndrome , 2006, Clinical endocrinology.

[53]  M. McCarthy,et al.  Development of polycystic ovary syndrome: involvement of genetic and environmental factors. , 2006, International journal of andrology.

[54]  F. Boisvert,et al.  The GAR Motif of 53BP1 is Arginine Methylated by PRMT1 and is Necessary for 53BP1 DNA Binding Activity , 2005, Cell cycle.

[55]  R. Roeder,et al.  Ordered Cooperative Functions of PRMT1, p300, and CARM1 in Transcriptional Activation by p53 , 2004, Cell.

[56]  G. Crooks,et al.  WebLogo: a sequence logo generator. , 2004, Genome research.

[57]  T. Crook,et al.  Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo , 2004, Oncogene.

[58]  B. Fauser,et al.  Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). , 2004, Human reproduction.

[59]  S. Caldeira,et al.  The role of TP53 in Cervical carcinogenesis , 2003, Human mutation.

[60]  C. Harris,et al.  The IARC TP53 database: New online mutation analysis and recommendations to users , 2002, Human mutation.

[61]  C. Prives,et al.  The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells , 2002, Oncogene.

[62]  J. Tilly,et al.  Oocyte apoptosis: like sand through an hourglass. , 1999, Developmental biology.

[63]  R. Lobo,et al.  Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women. , 1999, The Journal of clinical endocrinology and metabolism.

[64]  J. M. Kim,et al.  Involvement of the Fas/fas Ligand System in P53- Mediated Granulosa Cell Apoptosis during Follicular Development and Atresia* , 2022 .

[65]  E. Shaulian,et al.  Modulation of Mdm2 expression and p53-induced apoptosis in immortalized human ovarian granulosa cells. , 1998, Endocrinology.

[66]  J. Tilly Apoptosis and ovarian function. , 1996, Reviews of reproduction.

[67]  K Schulten,et al.  VMD: visual molecular dynamics. , 1996, Journal of molecular graphics.

[68]  M. Oren,et al.  Involvement of p53 expression in cAMP-mediated apoptosis in immortalized granulosa cells. , 1995, Experimental cell research.

[69]  R. Birgander,et al.  Is p53 polymorphism maintained by natural selection? , 1994, Human heredity.

[70]  Peter A. Jones,et al.  P16 gene in uncultured tumours , 1994, Nature.

[71]  J. Eppig,et al.  Interactions between somatic cells and germ cells throughout mammalian oogenesis. , 1990, Biology of reproduction.

[72]  Shirley A. Miller,et al.  A simple salting out procedure for extracting DNA from human nucleated cells. , 1988, Nucleic acids research.