Components and effectiveness of patient navigation programmes to increase participation to breast, cervical and colorectal cancer screening: A systematic review

BACKGROUND Inequalities in cancer incidence and mortality can be partly explained by unequal access to high-quality health services, including cancer screening. Several interventions have been described to increase access to cancer screening, among them patient navigation (PN), a barrier-focused intervention. This systematic review aimed to identify the reported components of PN and to assess the effectiveness of PN to promote breast, cervical and colorectal cancer screening. METHODS We searched Embase, PubMed and Web of Science Core Collection databases. The components of PN programmes were identified, including the types of barriers addressed by navigators. The percentage change in screening participation was calculated. RESULTS The 44 studies included were mainly on colorectal cancer and were conducted in the USA. All described their goals and community characteristics, and the majority reported the setting (97.7%), monitoring and evaluation (97.7%), navigator background and qualifications (81.4%) and training (79.1%). Supervision was only referred to in 16 studies (36.4%). Programmes addressed mainly barriers at the educational (63.6%) and health system level (61.4%), while only 25.0% reported providing social and emotional support. PN increased cancer screening participation when compared with usual care (0.4% to 250.6% higher) and educational interventions (3.3% to 3558.0% higher). CONCLUSION Patient navigation programmes are effective at increasing participation to breast, cervical and colorectal cancer screening. A standardized reporting of the components of PN programmes would allow their replication and a better measure of their impact. Understanding the local context and needs is essential to design a successful PN programme.

[1]  L. Fleisher,et al.  Barriers and opportunities to measuring oncology patient navigation impact: Results from the National Navigation Roundtable survey , 2022, Cancer.

[2]  Panpan Wang,et al.  Fundamental Elements in Training Patient Navigators and Their Involvement in Promoting Public Cervical Cancer Screening Knowledge and Practices: A Systematic Review , 2021, Cancer control : journal of the Moffitt Cancer Center.

[3]  J. Lortet-Tieulent,et al.  Profiling global cancer incidence and mortality by socioeconomic development , 2020, International journal of cancer.

[4]  R. E. Reed,et al.  Closing the Gap: A Resident-Led Quality Improvement Project to Improve Colorectal Cancer Screening in Primary Care Community Clinics. , 2020, Journal of graduate medical education.

[5]  H. D. de Koning,et al.  Effect of organised cervical cancer screening on cervical cancer mortality in Europe: a systematic review. , 2020, European journal of cancer.

[6]  H. D. de Koning,et al.  Evidence for reducing cancer-specific mortality due to screening for breast cancer in Europe: A systematic review. , 2020, European journal of cancer.

[7]  H. D. de Koning,et al.  Impact of colorectal cancer screening on cancer-specific mortality in Europe: A systematic review. , 2020, European journal of cancer.

[8]  L. Burhansstipanov,et al.  Findings from the National Navigation Roundtable: A call for competency‐based patient navigation training , 2019, Cancer.

[9]  K. Yeates,et al.  Patient navigation services for cancer care in low-and middle-income countries: A scoping review , 2019, PloS one.

[10]  E. Paskett,et al.  The efficacy and cost‐effectiveness of patient navigation programs across the cancer continuum: A systematic review , 2019, Cancer.

[11]  C. von Wagner,et al.  Using specialist screening practitioners (SSPs) to increase uptake of bowel scope (flexible sigmoidoscopy) screening: results of a feasibility single-stage phase II randomised trial , 2019, BMJ Open.

[12]  N. Nahcivan,et al.  The Effects of the Nurse Navigation Program in Promoting Colorectal Cancer Screening Behaviors: a Randomized Controlled Trial , 2018, Journal of Cancer Education.

[13]  M. Quinn,et al.  Economic assessment of patient navigation to colonoscopy‐based colorectal cancer screening in the real‐world setting at the University of Chicago Medical Center , 2018, Cancer.

[14]  R. Warnecke,et al.  Patient Navigation Improves Subsequent Breast Cancer Screening After a Noncancerous Result: Evidence from the Patient Navigation in Medically Underserved Areas Study. , 2018, Journal of women's health.

[15]  L. Guittet,et al.  Cost-Effectiveness Analysis of a Navigation Program for Colorectal Cancer Screening to Reduce Social Health Inequalities: A French Cluster Randomized Controlled Trial. , 2017, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[16]  D. Torgerson,et al.  A cluster randomized trial of strategies to increase uptake amongst young women invited for their first cervical screen: The STRATEGIC trial , 2017, Journal of medical screening.

[17]  L. Guittet,et al.  Patient navigation to reduce social inequalities in colorectal cancer screening participation: A cluster randomized controlled trial. , 2017, Preventive medicine.

[18]  Elizabeth A. Rohan,et al.  Patient Navigation for Colonoscopy Completion: Results of an RCT. , 2017, American journal of preventive medicine.

[19]  Barbara Jones,et al.  Increasing Breast and Cervical Cancer Screening in Rural and Border Texas with Friend to Friend Plus Patient Navigation , 2018, Journal of Cancer Education.

[20]  D. Torgerson,et al.  A cluster randomised trial of strategies to increase cervical screening uptake at first invitation (STRATEGIC). , 2016, Health technology assessment.

[21]  P. Hewett,et al.  Randomized evaluation and cost-effectiveness of HIV and sexual and reproductive health service referral and linkage models in Zambia , 2016, BMC Public Health.

[22]  Adrian H. Zai,et al.  Patient Navigation for Comprehensive Cancer Screening in High-Risk Patients Using a Population-Based Health Information Technology System: A Randomized Clinical Trial. , 2016, JAMA internal medicine.

[23]  Lisa M. Kath,et al.  Training in Patient Navigation , 2016, Health promotion practice.

[24]  L. K. Bartholomew,et al.  A non-randomized controlled stepped wedge trial to evaluate the effectiveness of a multi-level mammography intervention in improving appointment adherence in underserved women , 2015, Implementation Science.

[25]  R. Hajek,et al.  Patient navigation to increase colorectal cancer screening among Latino Medicare enrollees: a randomized controlled trial , 2015, Cancer Causes & Control.

[26]  K. Braun,et al.  Reducing Cancer Screening Disparities in Medicare Beneficiaries Through Cancer Patient Navigation , 2015, Journal of the American Geriatrics Society.

[27]  A. Rademaker,et al.  Sustaining mammography screening among the medically underserved: a follow-up evaluation. , 2015, Journal of women's health.

[28]  C. Pollack,et al.  Effect of Patient Navigation on Breast Cancer Screening Among African American Medicare Beneficiaries: A Randomized Controlled Trial , 2015, Journal of General Internal Medicine.

[29]  C. Pollack,et al.  Effect of patient navigation on colorectal cancer screening in a community-based randomized controlled trial of urban African American adults , 2015, Cancer Causes & Control.

[30]  S. Vernon,et al.  Increasing colon cancer screening in primary care among African Americans. , 2014, Journal of the National Cancer Institute.

[31]  Jeffrey M. Ashburner,et al.  The longitudinal impact of patient navigation on equity in colorectal cancer screening in a large primary care network , 2014, Cancer.

[32]  S. Vernon,et al.  Cost‐effectiveness of a standard intervention versus a navigated intervention on colorectal cancer screening use in primary care , 2014, Cancer.

[33]  J. Wyatt,et al.  Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide , 2014, BMJ : British Medical Journal.

[34]  Kisha I Coa,et al.  Key Considerations in Designing a Patient Navigation Program for Colorectal Cancer Screening , 2013, Health promotion practice.

[35]  A. Rademaker,et al.  Improving Mammography Screening Among the Medically Underserved , 2014, Journal of General Internal Medicine.

[36]  A. Rademaker,et al.  Improving colon cancer screening in community clinics , 2013, Cancer.

[37]  R. Luckmann,et al.  Referring patients for telephone counseling to promote colorectal cancer screening. , 2013, The American journal of managed care.

[38]  J. Ely,et al.  A Randomized Controlled Trial to Improve Colon Cancer Screening in Rural Family Medicine: An Iowa Research Network (IRENE) Study , 2013, The Journal of the American Board of Family Medicine.

[39]  J. Tobin,et al.  Telephone Outreach to Increase Colon Cancer Screening in Medicaid Managed Care Organizations: A Randomized Controlled Trial , 2013, The Annals of Family Medicine.

[40]  H. Freeman The history, principles, and future of patient navigation: commentary. , 2013, Seminars in oncology nursing.

[41]  S. Vernon,et al.  An Automated Intervention With Stepped Increases in Support to Increase Uptake of Colorectal Cancer Screening , 2013, Annals of Internal Medicine.

[42]  K. Emmons,et al.  Colorectal cancer screening among ethnically diverse, low-income patients: a randomized controlled trial. , 2011, Archives of internal medicine.

[43]  H. Jo,et al.  Evaluation of a navigator program for cancer screening of women in korean communities. , 2011, Asian Pacific journal of cancer prevention : APJCP.

[44]  K. Freund,et al.  Patient Navigation to Increase Mammography Screening Among Inner City Women , 2011, Journal of General Internal Medicine.

[45]  Tung T. Nguyen,et al.  Healthy colon, healthy life: a novel colorectal cancer screening intervention. , 2010, American journal of preventive medicine.

[46]  L. Burhansstipanov,et al.  Breast Screening Navigator Programs within Three Settings that Assist Underserved Women , 2010, Journal of Cancer Education.

[47]  Oncology Nursing Society, the Association of Oncology Social Work, and the National Association of Social Workers joint position on the role of oncology nursing and oncology social work in patient navigation. , 2010, Oncology nursing forum.

[48]  J. Wardle,et al.  Awareness of cancer symptoms and anticipated help seeking among ethnic minority groups in England , 2009, British Journal of Cancer.

[49]  K. Emmons,et al.  A multilevel intervention to promote colorectal cancer screening among community health center patients: results of a pilot study , 2009, BMC family practice.

[50]  Hae-Ra Han,et al.  Tailored lay health worker intervention improves breast cancer screening outcomes in non-adherent Korean-American women. , 2008, Health education research.

[51]  Jeffrey M. Ashburner,et al.  A Culturally Tailored Navigator Program for Colorectal Cancer Screening in a Community Health Center: A Randomized, Controlled Trial , 2009, Journal of General Internal Medicine.

[52]  J. Mandelblatt,et al.  Patient navigation: State of the art or is it science? , 2008, Cancer.

[53]  A. Flood,et al.  Translation of an Efficacious Cancer-Screening Intervention to Women Enrolled in a Medicaid Managed Care Organization , 2007, The Annals of Family Medicine.

[54]  L. Parkinson,et al.  Pressing the key pad: trial of a novel approach to health promotion advice. , 2005, Preventive medicine.

[55]  C. Gotay,et al.  Testing a culturally appropriate, theory-based intervention to improve colorectal cancer screening among Native Hawaiians. , 2005, Preventive medicine.

[56]  B. Thompson,et al.  A randomized controlled trial of interventions to promote cervical cancer screening among Chinese women in North America. , 2002, Journal of the National Cancer Institute.

[57]  T. Joiner,et al.  Health beliefs and illness attitudes as predictors of breast cancer screening attendance. , 2001, European journal of public health.

[58]  W. Barlow,et al.  Testing reminder and motivational telephone calls to increase screening mammography: a randomized study. , 2000, Journal of the National Cancer Institute.