Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice.

[1]  L. Biesecker,et al.  Patients with Bardet-Biedl syndrome have hyperleptinemia suggestive of leptin resistance. , 2011, The Journal of clinical endocrinology and metabolism.

[2]  A. Stunkard,et al.  An adoption study of human obesity. , 1986, The New England journal of medicine.

[3]  Nicholas H. Putnam,et al.  The Trichoplax genome and the nature of placozoans , 2008, Nature.

[4]  B. Fernandez,et al.  Clinical and genetic epidemiology of Bardet–Biedl syndrome in Newfoundland: A 22‐year prospective, population‐based, cohort study , 2005, American journal of medical genetics. Part A.

[5]  Nicholas H. Putnam,et al.  Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization , 2007, Science.

[6]  Ellen Kampman,et al.  Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity , 2009, Nature Genetics.

[7]  O. Rosen,et al.  Recent studies of the 3T3-L1 adipocyte-like cell line. , 1979, Recent progress in hormone research.

[8]  J. Friedman.  Modern science versus the stigma of obesity , 2004, Nature Medicine.

[9]  J. Naggert,et al.  New Alström syndrome phenotypes based on the evaluation of 182 cases. , 2005, Archives of internal medicine.

[10]  J. Shaw,et al.  Metabolic syndrome—a new world‐wide definition. A Consensus Statement from the International Diabetes Federation , 2006, Diabetic medicine : a journal of the British Diabetic Association.

[11]  Nicholas Katsanis,et al.  Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy. , 2009, The Journal of clinical investigation.

[12]  P. Rouzé,et al.  The FTO Gene, Implicated in Human Obesity, Is Found Only in Vertebrates and Marine Algae , 2007, Journal of Molecular Evolution.

[13]  P. Kopelman.  Obesity as a medical problem , 2000, Nature.

[14]  I. Farooqi,et al.  Genetic approaches to understanding human obesity. , 2011, The Journal of clinical investigation.

[15]  T. Wadden,et al.  Childhood onset (age less than 10) obesity has high familial risk. , 1990, International journal of obesity.

[16]  James Strait,et al.  Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits , 2007, PLoS genetics.

[17]  Peter Tontonoz,et al.  Fat and beyond: the diverse biology of PPARgamma. , 2008, Annual review of biochemistry.

[18]  M. Jarvelin,et al.  A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity , 2007, Science.

[19]  T. Wadden,et al.  Childhood onset (age < 10) obesity has high familial risk , 1990 .

[20]  Emma Lundberg,et al.  Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods , 2011, The EMBO journal.

[21]  Paul Zimmet,et al.  The metabolic syndrome—a new worldwide definition , 2005, The Lancet.

[22]  N. Petrovsky,et al.  Alström syndrome: insights into the pathogenesis of metabolic disorders , 2011, Nature Reviews Endocrinology.

[23]  A. Stunkard,et al.  A twin study of human obesity. , 1986, JAMA.

[24]  S. O’Rahilly,et al.  Genetics of obesity in humans. , 2006, Endocrine reviews.

[25]  H. Schiöth,et al.  The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. , 2008, Endocrinology.

[26]  Parvez Hossain,et al.  Obesity and diabetes in the developing world--a growing challenge. , 2007, The New England journal of medicine.

[27]  Christian Gieger,et al.  Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.

[28]  J. Kaprio,et al.  The heritability of body mass index among an international sample of monozygotic twins reared apart. , 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.