Magnetic Bar Array With Linker Technology for Detection and Investigation of Nonmagnetic Molecules

We have developed a simple method using a magnetic bar array to anchor nonmagnetic biomolecules for time-lapse analysis and identification. Biomolecules of interest are attached, using linker molecules, to the superparamagnetic beads which are in turn captured at gaps of the magnetic bar array. This micro-array system can be used for various studies and applications such as yeast growth studies, as illustrated in this work, and pyrosequencing. The technology is applicable to a wide variety of biomolecules using the suitable linker molecules, with the merits of low lost and reusability.