Successful term pregnancy after selective arterial embolization of symptomatic arteriovenous malformation in the setting of gestational trophoblastic tumor.

BACKGROUND Patients with arteriovenous malformations (AVMs) are at risk for significant vaginal hemorrhage, and are traditionally managed surgically. In the patient desiring future fertility, conservative management via selective arterial embolization is a reasonable option. Only a few cases have been previously reported of successful pregnancy after this procedure in the setting of gestational trophoblastic disease (GTD). CASE A 31-year-old gravida 1 para 0 was treated for persistent gestational trophoblastic tumor after a complete mole in 1997. She presented with heavy vaginal bleeding, and arteriogram demonstrated a large uterine AVM. The patient underwent selective uterine artery embolization with complete resolution of bleeding, as well as arteriographic cessation of flow through the AVM. After two first-trimester spontaneous abortions, the patient successfully completed a normal pregnancy, resulting in the forceps-assisted delivery of a healthy female infant. CONCLUSION Successful term pregnancy can occur after selective uterine artery embolization in women hemorrhaging from symptomatic GTD-associated AVM.

[1]  R. Berkowitz,et al.  Subsequent pregnancy experience in patients with molar pregnancy and gestational trophoblastic tumor. , 2002, The Journal of reproductive medicine.

[2]  A. Lim,et al.  Embolization of bleeding residual uterine vascular malformations in patients with treated gestational trophoblastic tumors. , 2002, Radiology.

[3]  H. Averette,et al.  Angiographic-guided embolization of metastatic invasive mole. , 1996, Gynecologic oncology.

[4]  M. Pearl,et al.  PERCUTANEOUS TRANSCATHETER EMBOLIZATION FOR CONTROL OF LIFE‐THREATENING PELVIC HEMORRHAGE FROM GESTATIONAL TROPHOBLASTIC DISEASE , 1992, Obstetrics and gynecology.

[5]  W. Poppe,et al.  Successful pregnancy after selective embolization of a post‐molar vascular malformation , 1989, British journal of obstetrics and gynaecology.

[6]  H. Loose,et al.  Successful pregnancy after selective embolization of a post‐molar vascular malformation. Case report , 1988, British journal of obstetrics and gynaecology.

[7]  P. Schwartz,et al.  Obstetric and nonmalignant gynecologic bleeding: treatment with angiographic embolization. , 1987, Radiology.

[8]  D. R. Chapman,et al.  Report of a successful delivery after nonsurgical management of a choriocarcinoma-related pelvic arteriovenous fistula. , 1985, American journal of obstetrics and gynecology.

[9]  W. Stern,et al.  Persistent angiographic abnormalities after cure of malignant trophoblastic disease. , 1968, Radiology.

[10]  K. Bagshawe,et al.  Pelvic arteriography in invasive trophoblastic neoplasia. , 1968, The British journal of radiology.

[11]  W. P. Cockshott,et al.  Persistent arteriovenous fistulae following chemotherapy of malignant trophoblastic disease. , 1967, Radiology.