T-cell integrins: more than just sticking points
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N. Hogg | M. Laschinger | Alison McDowall | Nancy Hogg | Melanie Laschinger | Katherine Giles | A. McDowall | K. Giles | A. Mcdowall
[1] H. Hamada,et al. Overexpression of CD82 on human T cells enhances LFA‐1 / ICAM‐1‐mediated cell‐cell adhesion: functional association between CD82 and LFA‐1 in T cell activation , 1999, European journal of immunology.
[2] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[3] P. Schwartzberg,et al. Beyond calcium: new signaling pathways for Tec family kinases. , 2002, Journal of cell science.
[4] J. Woska,et al. Characterization of molecular interactions between intercellular adhesion molecule-1 and leukocyte function- associated antigen-1. , 1996, Journal of immunology.
[5] C. Cabañas,et al. Paxillin Localizes to the Lymphocyte Microtubule Organizing Center and Associates with the Microtubule Cytoskeleton* , 2000, The Journal of Biological Chemistry.
[6] R. Ezzell,et al. Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18. , 1995, Journal of immunology.
[7] S. Kanner,et al. Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[8] N. Hogg,et al. Regulation of leukocyte integrin function: Affinity vs. avidity , 1996, Journal of cellular biochemistry.
[9] Stephen Shaw,et al. Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex , 2000, The Journal of experimental medicine.
[10] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[11] O. Barreiro,et al. A Novel Serine-rich Motif in the Intercellular Adhesion Molecule 3 Is Critical for Its Ezrin/Radixin/Moesin-directed Subcellular Targeting* , 2002, The Journal of Biological Chemistry.
[12] Y. Volkov,et al. Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes beta(I) and delta. , 1998, Journal of immunology.
[13] A. Trautmann,et al. The diversity of immunological synapses. , 2003, Current opinion in immunology.
[14] S. Kanner,et al. Focal adhesion kinase regulates β1 integrin‐dependent T cell migration through an HEF1 effector pathway , 2001, European journal of immunology.
[15] S. Kanner,et al. Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction. , 1998, The Journal of biological chemistry.
[16] Jason S. Mitchell,et al. Lipid Microdomain Clustering Induces a Redistribution of Antigen Recognition and Adhesion Molecules on Human T Lymphocytes1 , 2002, The Journal of Immunology.
[17] D. Schlaepfer,et al. Paxillin Binding to the α4 Integrin Subunit Stimulates LFA-1 (Integrin αLβ2)-Dependent T Cell Migration by Augmenting the Activation of Focal Adhesion Kinase/Proline-Rich Tyrosine Kinase-21 , 2003, The Journal of Immunology.
[18] N. Hogg,et al. The involvement of lipid rafts in the regulation of integrin function. , 2002, Journal of cell science.
[19] J M Miller,et al. Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. , 1996, The Journal of clinical investigation.
[20] N. Hogg,et al. Effects of I domain deletion on the function of the beta2 integrin lymphocyte function-associated antigen-1. , 2000, Molecular biology of the cell.
[21] S. Bromley,et al. The immunological synapse: a molecular machine controlling T cell activation. , 1999, Science.
[22] F. Sánchez‐Madrid,et al. Cytoskeletal rearrangement during migration and activation of T lymphocytes. , 1999, Trends in cell biology.
[23] J. Cannon,et al. The regulation of actin remodeling during T‐cell–APC conjugate formation , 2002, Immunological reviews.
[24] N. Hogg,et al. SKAP-55 regulates integrin adhesion and formation of T cell–APC conjugates , 2003, Nature Immunology.
[25] Keith Burridge,et al. RhoA is required for monocyte tail retraction during transendothelial migration , 2001, The Journal of cell biology.
[26] T. Kuijpers,et al. Leukocyte adhesion deficiency-type 1 (LAD-1)/variant: A novel immunodeficiency syndrome characterized by dysfunctional β2 integrins , 1997 .
[27] F. Sánchez‐Madrid,et al. Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes , 1999, European journal of immunology.
[28] Jason S. Mitchell,et al. Physical association and functional interaction between beta1 integrin and CD98 on human T lymphocytes. , 2003, Molecular immunology.
[29] M. Cybulsky,et al. α4β1 Integrin/VCAM-1 Interaction Activates αLβ2 Integrin-Mediated Adhesion to ICAM-1 in Human T Cells1 , 2000, The Journal of Immunology.
[30] D. T. Bogue,et al. Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes. , 1991, Journal of immunology.
[31] S. Levy,et al. Anti‐CD81 activates LFA‐1 on T cells and promotes T cell–B cell collaboration , 2001, European journal of immunology.
[32] E. Kaldjian,et al. Spatial and molecular organization of lymph node T cell cortex: a labyrinthine cavity bounded by an epithelium-like monolayer of fibroblastic reticular cells anchored to basement membrane-like extracellular matrix. , 2001, International immunology.
[33] C. Turner. Paxillin and focal adhesion signalling , 2000, Nature Cell Biology.
[34] N. Minato,et al. Rap 1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3OH Kinase , 2000 .
[35] G. Bazzoni,et al. Are changes in integrin affinity and conformation overemphasized? , 1998, Trends in biochemical sciences.
[36] Toshikazu Shirai,et al. Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration , 2001, Nature.
[37] N. Minato,et al. Rap1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3-OH Kinase , 2000, Molecular and Cellular Biology.
[38] K. Zänker,et al. CD4+ T lymphocytes migrating in three‐dimensional collagen lattices lack focal adhesions and utilize β1 integrin‐independent strategies for polarization, interaction with collagen fibers and locomotion , 1998, European journal of immunology.
[39] K. Kamiguchi,et al. Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration. , 1999, Journal of immunology.
[40] T. Yoshimura,et al. Discoidin domain receptor 1 isoform‐a (DDRla) promotes migration of leukocytes in three‐dimensional collagen lattices , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[41] Michael Loran Dustin,et al. The immunological synapse , 2002, Arthritis research.
[42] E. Marcantonio,et al. Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck. , 2003, Molecular biology of the cell.
[43] V. Koteliansky,et al. Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis , 2000 .
[44] C. Figdor,et al. Avidity regulation of integrins: the driving force in leukocyte adhesion. , 2000, Current opinion in cell biology.
[45] Sheila M. Thomas,et al. Binding of paxillin to α4 integrins modifies integrin-dependent biological responses , 1999, Nature.
[46] Mark V. Dahl,et al. α4 Integrins mediate lymphocyte attachment and rolling under physiologic flow , 1996 .
[47] P A Bates,et al. Genetic analysis of integrin function in man: LAD-1 and other syndromes. , 2000, Matrix biology : journal of the International Society for Matrix Biology.
[48] F. Sánchez‐Madrid,et al. Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis , 1997, The Journal of experimental medicine.
[49] F. Sánchez‐Madrid,et al. Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway , 1995, The Journal of cell biology.
[50] N. Hogg,et al. Signaling Through Integrin LFA-1 Leads to Filamentous Actin Polymerization and Remodeling, Resulting in Enhanced T Cell Adhesion1 , 2002, The Journal of Immunology.
[51] N. Hogg,et al. Mechanisms contributing to the activity of integrins on leukocytes , 2002, Immunological reviews.
[52] N. Hogg,et al. Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling , 2002, Nature Immunology.
[53] P. Hordijk,et al. Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes. , 2001, Molecular biology of the cell.
[54] L. Van Aelst,et al. Rac Regulates Integrin-Mediated Spreading and Increased Adhesion of T Lymphocytes , 1998, Molecular and Cellular Biology.
[55] Michael Loran Dustin,et al. Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration. , 2001, Current opinion in immunology.
[56] H. Nakauchi,et al. Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. , 1999, Immunity.
[57] S. Cunningham,et al. JAM2 interacts with alpha4beta1. Facilitation by JAM3. , 2002, The Journal of biological chemistry.
[58] S. Nourshargh,et al. PECAM-1 (CD31) Homophilic Interaction Up-Regulates α6β1 on Transmigrated Neutrophils In Vivo and Plays a Functional Role in the Ability of α6 Integrins to Mediate Leukocyte Migration through the Perivascular Basement Membrane , 2002, The Journal of experimental medicine.
[59] F. Alt,et al. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. , 2002, Immunity.
[60] María Yáñez-Mó,et al. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes , 2002, The Journal of cell biology.
[61] K. Okkenhaug,et al. Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice , 2002, Science.
[62] N. Hogg,et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. , 2003, The Journal of clinical investigation.
[63] M. A. Alonso,et al. The role of lipid rafts in signalling and membrane trafficking in T lymphocytes. , 2001, Journal of cell science.
[64] J. Cyster,et al. The CDM protein DOCK2 in lymphocyte migration. , 2002, Trends in cell biology.
[65] C. Weber,et al. Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines , 2001, Current Biology.
[66] G. O'Neill,et al. Integrin signalling: a new Cas(t) of characters enters the stage. , 2000, Trends in cell biology.
[67] F. Sánchez‐Madrid,et al. Leukocyte polarization in cell migration and immune interactions , 1999, The EMBO journal.
[68] N. Hogg,et al. T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1. , 1996, Journal of immunology.
[69] M. Ginsberg,et al. Integrin cytoplasmic domain-binding proteins. , 2000, Journal of cell science.
[70] Y. Volkov,et al. Crucial importance of PKC-β(I) in LFA-1–mediated locomotion of activated T cells , 2001, Nature Immunology.
[71] Amnon Peled,et al. Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions , 2000, The Journal of experimental medicine.
[72] M. Cybulsky,et al. Chemoattractants Induce a Rapid and Transient Upregulation of Monocyte α4 Integrin Affinity for Vascular Cell Adhesion Molecule 1 Which Mediates Arrest , 2001, The Journal of experimental medicine.
[73] W. Kolanus,et al. Actin Cytoskeletal Association of Cytohesin-1 Is Regulated by Specific Phosphorylation of Its Carboxyl-terminal Polybasic Domain* , 2001, The Journal of Biological Chemistry.
[74] B. Seed,et al. αLβ2 Integrin/LFA-1 Binding to ICAM-1 Induced by Cytohesin-1, a Cytoplasmic Regulatory Molecule , 1996, Cell.
[75] P. Cohen,et al. Phosphorylation of the Cytoplasmic Domain of the Integrin CD18 Chain by Protein Kinase C Isoforms in Leukocytes* , 2002, The Journal of Biological Chemistry.
[76] L. Bradley. Migration and T-lymphocyte effector function. , 2003, Current opinion in immunology.
[77] A. Zernecke,et al. JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes , 2002, Nature Immunology.
[78] W. Kolanus,et al. Phosphoinositide 3-OH Kinase Activates the β2Integrin Adhesion Pathway and Induces Membrane Recruitment of Cytohesin-1* , 1998, The Journal of Biological Chemistry.
[79] Michael Loran Dustin,et al. T Cell Receptor Signaling Precedes Immunological Synapse Formation , 2002, Science.
[80] M. Cybulsky,et al. Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap , 2001, Science.
[81] Yoji Shimizu,et al. Coupling of the TCR to Integrin Activation by SLAP-130/Fyb , 2001, Science.
[82] E. Bröcker,et al. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. , 2000, Immunity.
[83] T. Tsuruo,et al. Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow , 2003, The Journal of cell biology.
[84] W. Langdon,et al. Cbl: many adaptations to regulate protein tyrosine kinases , 2001, Nature Reviews Molecular Cell Biology.
[85] J. Cyster,et al. Integrin-dependence of Lymphocyte Entry into the Splenic White Pulp , 2003, The Journal of experimental medicine.
[86] R. Alon,et al. Chemokine Stimulation of Lymphocyte α4Integrin Avidity but Not of Leukocyte Function-associated Antigen-1 Avidity to Endothelial Ligands under Shear Flow Requires Cholesterol Membrane Rafts* , 2002, The Journal of Biological Chemistry.
[87] A. Ridley. Rho GTPases and cell migration. , 2001, Journal of cell science.
[88] T. Springer,et al. The critical cytoplasmic regions of the αL/β2 integrin in Rap1-induced adhesion and migration , 2003 .
[89] N. Hogg,et al. Vav1 transduces TCR signals required for LFA‐1 function and cell polarization at the immunological synapse , 2003, European journal of immunology.
[90] M. Schwartz,et al. Guanine Exchange-Dependent and -Independent Effects of Vav1 on Integrin-Induced T Cell Spreading , 2003, The Journal of Immunology.
[91] S. Pierce,et al. Floating the raft hypothesis: lipid rafts play a role in immune cell activation. , 2001, Immunity.
[92] B. Engelhardt,et al. Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro , 2000, Journal of Neuroimmunology.
[93] Rangarajan Sampath,et al. Cytoskeletal Interactions with the Leukocyte Integrin β2 Cytoplasmic Tail , 1998, The Journal of Biological Chemistry.
[94] S. Fagerholm,et al. The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester‐activated cells correlates with CD18 phosphorylation , 1999, European journal of immunology.
[95] L. Ruuls-Van Stalle,et al. LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: relevance for invasion and migration of a T cell hybridoma. , 1999, Journal of immunology.
[96] M. Abercrombie. The bases of the locomotory behaviour of fibroblasts. , 1961, Experimental cell research.
[97] E. Kremmer,et al. Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration , 2003, The EMBO journal.
[98] N. Hogg,et al. The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes. , 1999, Molecular biology of the cell.
[99] N. Hogg,et al. LFA-1–mediated Adhesion Is Regulated by Cytoskeletal Restraint and by a Ca2+-dependent Protease, Calpain , 1998, The Journal of cell biology.
[100] C. Mackay,et al. T-cell function and migration. Two sides of the same coin. , 2000, The New England journal of medicine.
[101] M. Lichtman,et al. Protein kinase C modulates actin conformation in human T lymphocytes. , 1988, Journal of immunology.
[102] L. Piccio,et al. Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. , 2000, Immunity.
[103] Nigel Klein,et al. A novel form of integrin dysfunction involving β1, β2, and β3 integrins , 2003 .
[104] R. Sampath,et al. Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin. , 1998, The Journal of biological chemistry.
[105] Y. Qiu,et al. A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T‐cell receptor , 2001, The EMBO journal.
[106] R. V. van Lier,et al. Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins. , 1997, The Journal of clinical investigation.
[107] D. Chang,et al. Rack1, a Receptor for Activated Protein Kinase C, Interacts with Integrin β Subunit* , 1998, The Journal of Biological Chemistry.
[108] Anne J. Ridley,et al. ROCKs: multifunctional kinases in cell behaviour , 2003, Nature Reviews Molecular Cell Biology.
[109] B. Burgering,et al. Binding of protein kinase B to the plakin family member periplakin , 2002, Journal of Cell Science.
[110] C. Martínez-A,et al. Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[111] R. Alon,et al. The Src Kinase p56 lck Up-regulates VLA-4 Integrin Affinity , 2001, The Journal of Biological Chemistry.
[112] Joanna C. Porter,et al. LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment , 2003, Journal of Cell Science.
[113] T. Udagawa,et al. Control of T lymphocyte morphology by the GTPase Rho , 2003, BMC Cell Biology.
[114] Colin R. F. Monks,et al. Three-dimensional segregation of supramolecular activation clusters in T cells , 1998, Nature.
[115] Yun-Cai Liu,et al. Negative Regulation of T Cell Antigen Receptor-mediated Crk-L-C3G Signaling and Cell Adhesion by Cbl-b* , 2003, Journal of Biological Chemistry.
[116] E. Butcher,et al. Lymphocyte trafficking and regional immunity. , 1999, Advances in immunology.
[117] C. Cabañas,et al. Rho and Rho-associated Kinase Modulate the Tyrosine Kinase PYK2 in T-cells through Regulation of the Activity of the Integrin LFA-1* , 2001, The Journal of Biological Chemistry.
[118] R. Adams,et al. A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. , 2001, Blood.
[119] M. Miyasaka,et al. Lymphocyte binding to MAdCAM-1 via α4β7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin and p105Cas-L , 2002 .
[120] Mark J. Miller,et al. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[121] K. Nagashima,et al. DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines. , 2002, Blood.
[122] Y. Volkov,et al. Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells. , 2001, Nature immunology.
[123] Jessica L. Dunne,et al. Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1. , 2002, Blood.
[124] P. Altevogt,et al. Integrin Leukocyte Function-associated Antigen-1-mediated Cell Binding Can Be Activated by Clustering of Membrane Rafts* , 1999, The Journal of Biological Chemistry.
[125] S. Feller. Crk family adaptors–signalling complex formation and biological roles , 2001, Oncogene.
[126] C. Figdor,et al. Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion , 1994, The Journal of cell biology.
[127] K. Katagiri,et al. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1 , 2003, Nature Immunology.
[128] M. Hemler,et al. Evaluation of Prototype Transmembrane 4 Superfamily Protein Complexes and Their Relation to Lipid Rafts* , 2001, The Journal of Biological Chemistry.
[129] W. Muller. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. , 2003, Trends in immunology.
[130] N. Hogg,et al. Integrin Cross Talk: Activation of Lymphocyte Function-associated Antigen-1 on Human T Cells Alters α4β1- and α5β1-mediated Function , 1997, The Journal of cell biology.
[131] D. Staunton,et al. A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow. , 2003, Blood.
[132] K. Nagashima,et al. DOCK 2 associates with CrkL and regulates Rac 1 in human leukemia cell lines , 2002 .