THE SUPPORT OFFERED BY THE ROMANIAN PRIMARY ACTIVITY STANDARD LABORATORY TO THE NUCLEAR MEDICINE FIELD

The paper presents the involvement of the Radionuclide Metrology Laboratory from IFIN-HH, Romania, in the assurance of the correct measurement of radiopharmaceuticals activity in nuclear medicine. Development and international validation of primary standards, development of secondary standards and direct support offered to the domain, consisting from calibration services and organization of comparisons/ proficiency tests, are presented. Analysis of the results obtained in the calibration of several types of radionuclide calibrators during a six years period is done. It includes the following actions: check of the measurement uncertainty, recalibration when necessary, control of the calibrators’ behavior in time. A comparison between calibration check and the results of the participation of the staff at proficiency tests is done.

[1]  Sahagia Maria,et al.  Role of the Radionuclide Metrology in Nuclear Medicine , 2011 .

[2]  P. Cassette,et al.  Standardization, decay data measurements and evaluation of 64Cu. , 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[3]  A. Luca,et al.  Assurance of the traceability chain for 131I measurement. , 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[4]  M Sahagia,et al.  Results of an international comparison for the activity measurement of 177Lu. , 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[5]  B. Zimmerman,et al.  Results of an international comparison of 57Co. , 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[6]  A. C. Wätjen,et al.  IFIN-HH ionization chamber calibration and its validation; electrometric system improvement. , 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[7]  A. Luca,et al.  Standardization of 64Cu and 68Ga by the 4π(PC)β-γ coincidence method and calibration of the ionization chamber. , 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[8]  Christian Negut,et al.  Standardization of 68(Ge+Ga). , 2004, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[9]  Maria Sahagia,et al.  Participation in the CCRI(II)-K2.H-3 comparison and study of the new TDCR-LS counter with 6 CPMs. , 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[10]  K. Shortt,et al.  Establishing measurement traceability for national laboratories: Results of an IAEA comparison of (131)I. , 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[11]  B. Zimmerman,et al.  Standardization of 68Ge/68Ga Using Three Liquid Scintillation Counting Based Methods , 2008, Journal of research of the National Institute of Standards and Technology.

[12]  V. Olšovcová,et al.  National comparison of 131I measurement among nuclear medicine clinics of eight countries. , 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[13]  F. Maringer,et al.  Results of the IFIN-HH (Romania), KRISS (Republic of Korea), CMI (Czech Republic) and the BEV (Austria) in the BIPM comparison BIPM.RI(II)-K1.I-131 of activity measurements of the radionuclide 131I , 2008 .

[14]  P. Cassette,et al.  Standardization of 89Sr. , 2002, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[15]  A. Luca,et al.  Precise measurement of the activity of 186Re, 188Re radiopharmaceuticals. , 2002, Applied Radiation and Isotopes.