A Tapered Phased Array Ultrasound Transducer for Hyperthermia Treatment

Abstracl-An ultrasonic tapered phased array transducer, consisting of a linear phased array employing elements with a tapered thickness, was developed to study the feasibility of its use for hyperthermic treatment of deep-seated tumors. The cylindrical focal region is generated and steered in two dimensions by controlling the phases of the driving signals on each element and moved in the third dimension by changing the driving frequency. Experimentally obtained field intensity distributions are in good agreement with theoretical predictions. Acoustical power output measurements indicate that tapered phased arrays are capable of providing the intensities necessary for producing therapeutic temperatures in tumors.

[1]  E. Seppi,et al.  A Large Aperture Ultrasonic Array System for Hyperthermia Treatment of Deep-Seated Tumors , 1985, IEEE 1985 Ultrasonics Symposium.

[2]  Song Cw.  Physiological factors in hyperthermia. , 1982 .

[3]  P. Corry,et al.  Human Cancer Treatment with Ultrasound , 1984, IEEE Transactions on Sonics and Ultrasonics.

[4]  W. Swindell,et al.  Simulation of Focused, Scanned Ultrasonic Heating of Deep-Seated Tumors: The Effect of Blood Perfusion , 1984, IEEE Transactions on Sonics and Ultrasonics.

[5]  F. Kremkau,et al.  Cancer therapy with ultrasound: A historical review , 1979, Journal of clinical ultrasound : JCU.

[6]  A W Guy,et al.  Calculations of therapeutic heat generated by ultrasound in fat-muscle-bone layers. , 1974, IEEE transactions on bio-medical engineering.

[7]  C. Durney,et al.  Hyperthermia production for cancer therapy: a review of fundamentals and methods. , 1981, The Journal of microwave power.

[8]  P. P. Lele,et al.  Temperature distributions in tissues during local hyperthermia by stationary or steered beams of unfocused or focused ultrasound. , 1982, The British journal of cancer. Supplement.

[9]  Don Berlincourt,et al.  3 – Piezoelectric and Piezomagnetic Materials and Their Function in Transducers , 1964 .

[10]  A. Macovski.  Ultrasonic imaging using arrays , 1979, Proceedings of the IEEE.

[11]  Leon A. Frizzell,et al.  Ultrasound Phased Arrays for Hyperthermia Treatment , 1985, IEEE 1985 Ultrasonics Symposium.

[12]  Herbert L. Abrams,et al.  An Ultrasonic Phased Array Applicator for Hyperthermia , 1984 .

[13]  John W. Strohbehn,et al.  Experience with a Multitransducer Ultrasound System for Localized Hyperthermia of Deep Tissues , 1984, IEEE Transactions on Biomedical Engineering.

[14]  Don Berlincourt,et al.  Piezoelectric Crystals and Ceramics , 1971 .

[15]  Robert J. Dickinson,et al.  An Ultrasound System for Local Hyperthermia Using Scanned Focused Transducers , 1984, IEEE Transactions on Biomedical Engineering.

[16]  R. Mladick.  Treatment of superficial human neoplasms by local hyperthermia induced by ultrasound , 1979 .

[17]  G. Hahn,et al.  SOME HEAT TRANSFER PROBLEMS ASSOCIATED WITH HEATING BY ULTRASOUND, MICROWAVES, OR RADIO FREQUENCY * , 1980, Annals of the New York Academy of Sciences.

[18]  P. P. Lele,et al.  Induction of deep, local hyperthermia by ultrasound and electromagnetic fields , 1980, Radiation and environmental biophysics.

[19]  G. Hahn.  Hyperthermia for the Engineer: A Short Biological Primer , 1984, IEEE Transactions on Biomedical Engineering.