COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF TRIPLE ANTIBIOTIC PASTE AND MODIFIED DOUBLE ANTIBIOTIC PASTE USING DIFFERENT VEHICLES AGAINST ENTEROCOCCUS FAECALIS

Microorganisms and their products are considered as the etiological agents of pulp necrosis and periradicular lesions. Many studies have reported that E. faecalis is cultured in higher frequency from root canals of teeth with failed endodontic treatment. To ensure complete elimination of root canal bacteria, an effective antimicrobial agent in the root canal is required. So, the aim of the present study was to evaluate the antimicrobial activity of triple antibiotic and modified double antibiotic paste with different vehicles against E.faecalis. The antimicrobial effect was evaluated by the direct contact with agar diffusion method. The freshly prepared medicaments were placed in wells on agar plates inoculated with different microorganisms. All plates were incubated and the diameter of bacterial inhibition zones on agar plate was measured in millimeters at 24, 48 and 72 hours at 37°C and 100% humidity. The results showed that the Modified Double antibiotic paste irrespective of vehicle was more effective than triple antibiotic paste against E.faecalis.