Efficacy of Bioshell Calcium Oxide Water as Disinfectants to Enable Face Mask Reuse.

Bioshell calcium oxide (BiSCaO) is derived from scallop shells and after heat treatment exhibits broad microbicidal activity. BiSCaO Water is a disinfectant prepared by collecting the aqueous layer after adding BiSCaO powder to water, is colorless and transparent, and has a pH of 12.8. We compared the utility of commercially available BiSCaO Water, ethanol, sodium hypochlorite, hypochlorous acid and hydrogen peroxide solutions as sterilization agents to enable the reuse of surgical and N95 face masks. The microbicidal efficacy of each disinfectant was evaluated using pieces of surgical and N95 face masks contaminated with normal bacterial flora. The results suggest that BiSCaO Water has excellent disinfection activity toward contaminated polypropylene masks and has minimal adverse effect on the structure of non-woven masks.

[1]  Shingo Nakamura,et al.  Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes , 2020, Molecules.

[2]  Shingo Nakamura,et al.  Bioshell Calcium Oxide-Containing Liquids as a Sanitizer for the Reduction of Histamine Production in Raw Japanese Pilchard, Japanese Horse Mackerel, and Chub Mackerel , 2020, Foods.

[3]  Shingo Nakamura,et al.  Concentrated Bioshell Calcium Oxide (BiSCaO) Water Kills Pathogenic Microbes: Characterization and Activity , 2020, Molecules.

[4]  S. Grinshpun,et al.  Autoclave sterilization and ethanol treatment of re-used surgical masks and N95 respirators during COVID-19: impact on their performance and integrity , 2020, Journal of Hospital Infection.

[5]  Shingo Nakamura,et al.  Bioshell Calcium Oxide (BiSCaO) Ointment for the Disinfection and Healing of Pseudomonas aeruginosa-Infected Wounds in Hairless Rats , 2020, International journal of molecular sciences.

[6]  J. Rubio-Romero,et al.  Disposable masks: Disinfection and sterilization for reuse, and non-certified manufacturing, in the face of shortages during the COVID-19 pandemic , 2020, Safety Science.

[7]  S. Chu,et al.  Can N95 Respirators Be Reused after Disinfection? How Many Times? , 2020, ACS nano.

[8]  J. Henckel,et al.  COVID-19 coronavirus: recommended personal protective equipment for the orthopaedic and trauma surgeon , 2020, Knee Surgery, Sports Traumatology, Arthroscopy.

[9]  G. Kampf,et al.  Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents , 2020, Journal of Hospital Infection.

[10]  Shingo Nakamura,et al.  Skin Cleansing Technique with Disinfectant using Improved High-Velocity Steam-Air Micromist Jet Spray. , 2020, Biocontrol science.

[11]  Shingo Nakamura,et al.  Application of Colloidal Dispersions of Bioshell Calcium Oxide (BiSCaO) for Disinfection , 2019, Polymers.

[12]  Shingo Nakamura,et al.  Preparation and Application of Bioshell Calcium Oxide (BiSCaO) Nanoparticle-Dispersions with Bactericidal Activity , 2019, Molecules.

[13]  M. Xiang,et al.  Absorption Characteristics of Novel Compound Calcium Carbonate Granules: Effects of Gastric Acid Deficiency and Exogenous Weak Acids , 2019, Current Medical Science.

[14]  C. Turssi,et al.  Anti-erosive effect of calcium carbonate suspensions , 2018, Journal of clinical and experimental dentistry.

[15]  Shingo Nakamura,et al.  Stability of Weakly Acidic Hypochlorous Acid Solution with Microbicidal Activity. , 2017, Biocontrol science.

[16]  Shingo Nakamura,et al.  Adsorption of Silver Nanoparticles onto Different Surface Structures of Chitin/Chitosan and Correlations with Antimicrobial Activities , 2015, International journal of molecular sciences.

[17]  J. Sawai,et al.  Heated scallop-shell powder treatment for deactivation and removal of Listeria sp. biofilm formed at a low temperature. , 2015, Biocontrol science.

[18]  T. Kuwahara,et al.  Antimicrobial activity and stability of weakly acidified chlorous acid water. , 2015, Biocontrol science.

[19]  Takeshi Ono,et al.  Development of antimicrobial biomaterials produced from chitin-nanofiber sheet/silver nanoparticle composites , 2014, Journal of Nanobiotechnology.

[20]  Hakimullah Hakim,et al.  Inactivation of Avian Influenza Virus, Newcastle Disease Virus and Goose Parvovirus Using Solution of Nano-Sized Scallop Shell Powder , 2014, The Journal of veterinary medical science.

[21]  Takashi Watanabe,et al.  Antibacterial characteristics of heated scallop-shell nano-particles. , 2014, Biocontrol science.

[22]  J. Sawai,et al.  Disinfection Treatment of Heated Scallop-Shell Powder on Biofilm of Escherichia coli ATCC 25922 Surrogated for E. coli O157:H7 , 2013 .

[23]  W. Cao,et al.  Disinfection effectiveness of slightly acidic electrolysed water in swine barns , 2013, Journal of applied microbiology.

[24]  J. Sawai,et al.  Ability of Heated Scallop-Shell Powder to Disinfect Staphylococcus aureus Biofilm , 2013 .

[25]  Huahua Yu,et al.  Comparison of antifungal activities of scallop shell, oyster shell and their pyrolyzed products , 2013 .

[26]  R. Duval,et al.  Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic Strategies , 2012, Viruses.

[27]  J. Sawai Antimicrobial characteristics of heated scallop shell powder and its application. , 2011, Biocontrol science.

[28]  A. Ardizzoni,et al.  An in vitro and ex vivo study on two antibiotic-based endodontic irrigants: a challenge to sodium hypochlorite. , 2009, The new microbiologica.

[29]  S. Fukuzaki Mechanisms of actions of sodium hypochlorite in cleaning and disinfection processes. , 2006, Biocontrol science.

[30]  D. Royse,et al.  Influence of precipitated calcium carbonate (CaCO3) on shiitake (Lentinula edodes) yield and mushroom size. , 2003, Bioresource technology.

[31]  J. Sawai,et al.  Sporicidal kinetics of Bacillus subtilis spores by heated scallop shell powder. , 2003, Journal of food protection.