Inhibition of Colony-Stimulating Factor-1 Receptor Enhances the Efficacy of Radiotherapy and Reduces Immune Suppression in Glioblastoma
暂无分享,去创建一个
C. Miller | Shiva Kant | Pravin Kesarwani | M. Almahariq | P. Chinnaiyan | T. Quinn | S. Kant | THOMAS J. Quinn | C. R. Miller
[1] A. Baschnagel,et al. Prognostic significance of MTOR expression in HPV positive and negative head and neck cancers treated by chemoradiation , 2020, Head & neck.
[2] Christopher M. Jackson,et al. Mechanisms of immunotherapy resistance: lessons from glioblastoma , 2019, Nature Immunology.
[3] Shiva Kant,et al. Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma , 2019, Cancer Immunology, Immunotherapy.
[4] V. Zagonel,et al. PD-1/PD-L1 immune-checkpoint inhibitors in glioblastoma: A concise review. , 2019, Critical reviews in oncology/hematology.
[5] D. Ottaviani,et al. Harnessing the immune system in glioblastoma , 2018, British Journal of Cancer.
[6] C. Castañeda,et al. Distribution of tumor-infiltrating immune cells in glioblastoma , 2018, CNS oncology.
[7] J. Allison,et al. Fundamental Mechanisms of Immune Checkpoint Blockade Therapy. , 2018, Cancer discovery.
[8] C. Miller,et al. Tryptophan Metabolism Contributes to Radiation-Induced Immune Checkpoint Reactivation in Glioblastoma , 2018, Clinical Cancer Research.
[9] M. Ernst,et al. Targeting Macrophages in Cancer: From Bench to Bedside , 2018, Front. Oncol..
[10] C. James,et al. IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma , 2018, Clinical Cancer Research.
[11] Y. Delneste,et al. The roles of CSFs on the functional polarization of tumor‐associated macrophages , 2018, The FEBS journal.
[12] Steven P. Angus,et al. Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma , 2017, Neuro-oncology.
[13] Hanmei Xu,et al. Tumor-related interleukins: old validated targets for new anti-cancer drug development , 2017, Molecular Cancer.
[14] S. Lucas,et al. Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies , 2017, Front. Immunol..
[15] Edward F. Chang,et al. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. , 2017, Cancer cell.
[16] A. Brandes,et al. OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143 , 2017 .
[17] P. Murray. Macrophage Polarization. , 2017, Annual review of physiology.
[18] A. Bergenheim,et al. Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study , 2016, Journal of Neuro-Oncology.
[19] C. Miller,et al. Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide. , 2016, Neuro-oncology.
[20] Sarah I. Alothman,et al. Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice. , 2016, Gastroenterology.
[21] J. Brown,et al. Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization. , 2016, Neuro-oncology.
[22] Eric C. Holland,et al. The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas , 2016, Science.
[23] M. Prados,et al. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. , 2016, Neuro-oncology.
[24] Xinchen Sun,et al. Effects of radiation on T regulatory cells in normal states and cancer: mechanisms and clinical implications. , 2015, American journal of cancer research.
[25] T. Rőszer,et al. Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms , 2015, Mediators of inflammation.
[26] F. Paris,et al. Radiation-induced PGE2 sustains human glioma cell growth and survival through EGF signaling , 2015, Oncotarget.
[27] T. van Dyke,et al. A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors , 2014, Disease Models & Mechanisms.
[28] Jill S. Barnholtz-Sloan,et al. CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012 , 2015, Neuro-oncology.
[29] S. Formenti,et al. Myeloid-derived cells in tumors: effects of radiation. , 2015, Seminars in radiation oncology.
[30] C. Miller,et al. Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis. , 2013, Neuro-oncology.
[31] Christina S. Leslie,et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression , 2013, Nature Medicine.
[32] A. Sica,et al. Macrophage plasticity and polarization in tissue repair and remodelling , 2013, The Journal of pathology.
[33] J. DeMarco,et al. Radiation enhances regulatory T cell representation. , 2011, International journal of radiation oncology, biology, physics.
[34] A. Unterberg,et al. Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β , 2011, Clinical Cancer Research.
[35] R. Mirimanoff,et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. , 2009, The Lancet. Oncology.
[36] David J. Yang,et al. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. , 2006, Neuro-oncology.