The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson’s disease

Pilot studies suggest that adaptive deep brain stimulation (DBS) may be more effective than conventional DBS for the treatment of Parkinson's disease. Tinkhauser et al. show that adaptive DBS regulates pathological beta synchronisation in the subthalamic nucleus by selectively limiting long duration beta bursts, which are related to clinical impairment.

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