Overexpression of miR-32 in Chinese hamster ovary cells increases production of Fc-fusion protein
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M. Karimipoor | M. Azizi | A. Adeli | N. Davoudi | M. Bazaz | F. Mahboudi
[1] M. Soleimani,et al. Recent developments in miRNA based recombinant protein expression in CHO , 2022, Biotechnology Letters.
[2] Alana C Szkodny,et al. Biopharmaceutical Manufacturing: Historical Perspectives and Future Directions. , 2022, Annual review of chemical and biomolecular engineering.
[3] M. Andersen,et al. Identification of novel miRNA targets in CHO cell lines and characterization of their impact on protein N-glycosylation , 2022 .
[4] D. Weinberger,et al. Aflibercept clearance through the drainage system in a rat model , 2021, International Journal of Retina and Vitreous.
[5] Yongfeng Hui,et al. miR-32-5p suppresses the proliferation and migration of pancreatic adenocarcinoma cells by targeting TLDC1 , 2021, Molecular medicine reports.
[6] Vladimir Benes,et al. Web-based LinRegPCR: application for the visualization and analysis of (RT)-qPCR amplification and melting data , 2021, BMC Bioinformatics.
[7] Chi Zhou,et al. miR-32-5p Inhibits the Proliferation, Migration and Invasion of Thyroid Cancer Cells by Regulating Twist1 , 2021 .
[8] Asher Mullard. FDA approves 100th monoclonal antibody product , 2021, Nature Reviews Drug Discovery.
[9] J. Kalinowski,et al. Exploring the molecular content of CHO exosomes during bioprocessing , 2021, Applied Microbiology and Biotechnology.
[10] H. Xiong,et al. Roles of BTLA in Immunity and Immune Disorders , 2021, Frontiers in Immunology.
[11] Shikai Liu,et al. MicroRNA-32 promotes ovarian cancer cell proliferation and motility by targeting SMG1 , 2020, Oncology letters.
[12] M. Butler,et al. Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing. , 2020, Biotechnology advances.
[13] L.-M. Wang,et al. Overexpression of miR-32 inhibits the proliferation and metastasis of ovarian cancer cells by targeting BTLA. , 2020, European review for medical and pharmacological sciences.
[14] P. Shamlou,et al. Inhibition of endogenous miR‐23a/miR‐377 in CHO cells enhances difficult‐to‐express recombinant lysosomal sulfatase activity , 2020, Biotechnology progress.
[15] Z. Du,et al. High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells , 2019, PloS one.
[16] Buchang Zhang,et al. MiR-106b promotes therapeutic antibody expression in CHO cells by targeting deubiquitinase CYLD , 2019, Applied Microbiology and Biotechnology.
[17] M. Rajabibazl,et al. Development of an improved lentiviral based vector system for the stable expression of monoclonal antibody in CHO cells , 2019, Preparative biochemistry & biotechnology.
[18] H. Chen,et al. MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma , 2019, Technology in cancer research & treatment.
[19] Vaibhav Jadhav,et al. CRISPR/Cas9-Mediated Knockout of MicroRNA-744 Improves Antibody Titer of CHO Production Cell Lines. , 2019, Biotechnology journal.
[20] L. Chen,et al. MicroRNA-32 inhibits the proliferation, migration and invasion of human colon cancer cell lines by targeting E2F transcription factor 5. , 2019, European review for medical and pharmacological sciences.
[21] M. Andersen,et al. CRISPR/Cas9-Multiplexed Editing of Chinese Hamster Ovary B4Gal-T1, 2, 3, and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins. , 2018, Biotechnology journal.
[22] J. Andersen,et al. Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties , 2018, Scientific Reports.
[23] J. Shiloach,et al. Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells , 2018, Genes.
[24] A. Wagner,et al. miR‐143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult‐to‐express proteins , 2017, Biotechnology progress.
[25] Carlo M. Croce,et al. Small non-coding RNA and cancer , 2017, Carcinogenesis.
[26] W. P. Loh,et al. miR-92a enhances recombinant protein productivity in CHO cells by increasing intracellular cholesterol levels. , 2017, Biotechnology journal.
[27] W. Xia,et al. MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7 , 2017, Cancer Cell International.
[28] P. Khaw,et al. Fc-fusion mimetics. , 2016, Biomaterials science.
[29] A. Sczyrba,et al. miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant targets for host cell engineering. , 2016, Journal of biotechnology.
[30] S. Kochanek,et al. Temperature‐sensitive miR‐483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells , 2016, Biotechnology and bioengineering.
[31] Lei Li,et al. miR-32 inhibits proliferation, epithelial–mesenchymal transition, and metastasis by targeting TWIST1 in non-small-cell lung cancer cells , 2016, OncoTargets and therapy.
[32] Yong Peng,et al. The role of MicroRNAs in human cancer , 2016, Signal Transduction and Targeted Therapy.
[33] Simon Fischer,et al. The art of CHO cell engineering: A comprehensive retrospect and future perspectives. , 2015, Biotechnology advances.
[34] Simon Fischer,et al. Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway. , 2015, Journal of biotechnology.
[35] Zhefu Ma,et al. MiR-32 contributed to cell proliferation of human breast cancer cells by suppressing of PHLPP2 expression. , 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[36] C. Gallagher,et al. Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. , 2015, Biotechnology journal.
[37] C. Gallagher,et al. Conserved microRNA function as a basis for Chinese hamster ovary cell engineering , 2015, Biotechnology Letters.
[38] Yu-Qin Wang,et al. MiR-32 induces cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting PTEN , 2015, Tumor Biology.
[39] Alexandra B. Graf,et al. Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation , 2014, Applied Microbiology and Biotechnology.
[40] Weibin Zhang,et al. RETRACTED ARTICLE: MicroRNA-32 inhibits osteosarcoma cell proliferation and invasion by targeting Sox9 , 2014, Tumor Biology.
[41] Vaibhav Jadhav,et al. Stable overexpression of miR-17 enhances recombinant protein production of CHO cells☆ , 2014, Journal of biotechnology.
[42] Jeffry D. Sander,et al. CRISPR-Cas systems for editing, regulating and targeting genomes , 2014, Nature Biotechnology.
[43] David P. Kreil,et al. CHO microRNA engineering is growing up: Recent successes and future challenges☆ , 2013, Biotechnology advances.
[44] Yih Yean Lee,et al. Identification and expression analysis of miRNAs during batch culture of HEK-293 cells. , 2009, Journal of biotechnology.
[45] Niraj Kumar,et al. Initial identification of low temperature and culture stage induction of miRNA expression in suspension CHO-K1 cells. , 2007, Journal of biotechnology.
[46] Niraj Kumar,et al. Proliferation control strategies to improve productivity and survival during CHO based production culture , 2007, Cytotechnology.
[47] Zhiwei Song,et al. RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cells. , 2006, Metabolic engineering.
[48] G. Yancopoulos,et al. VEGF-Trap: A VEGF blocker with potent antitumor effects , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[49] Danni Qu,et al. MiR-32-5p regulates the proliferation and metastasis of cervical cancer cells by targeting HOXB8. , 2019, European review for medical and pharmacological sciences.
[50] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..