Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism
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Iain G. Johnston | Joerg P Burgstaller | Vitezslav Havlicek | Thomas Kolbe | Thomas Rülicke | Nick S Jones | Iain G Johnston | Gottfried Brem | T. Rülicke | I. Johnston | N. Jones | G. Brem | J. Poulton | T. Kolbe | J. Burgstaller | V. Havlícek | Jo Poulton
[1] B. Levy,et al. Blastocyst preimplantation genetic diagnosis (PGD) of a mitochondrial DNA disorder. , 2012, Fertility and sterility.
[2] David C Samuels,et al. A model of the nuclear control of mitochondrial DNA replication. , 2003, Journal of theoretical biology.
[3] R. Youle,et al. Mechanisms of mitophagy , 2010, Nature Reviews Molecular Cell Biology.
[4] A. Munnich,et al. Segregation of mtDNA Throughout Human Embryofetal Development: m.3243A > G as a Model System , 2010, Human mutation.
[5] W. K. Hastings,et al. Monte Carlo Sampling Methods Using Markov Chains and Their Applications , 1970 .
[6] Louis Brand,et al. A Sequence Defined by a Difference Equation , 1955 .
[7] Y. Peterson,et al. Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy , 2012, Nature chemical biology.
[8] Martin H. Johnson,et al. Variations in mouse mitochondrial DNA copy number from fertilization to birth are associated with oxidative stress. , 2008, Reproductive biomedicine online.
[9] A. Munnich,et al. Analysis of mtDNA variant segregation during early human embryonic development: a tool for successful NARP preimplantation diagnosis , 2005, Journal of Medical Genetics.
[10] E. Wolf,et al. Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning , 2000, Nature Genetics.
[11] M. Gutmann,et al. Approximate Bayesian Computation , 2012 .
[12] Iain G Johnston,et al. Efficient parametric inference for stochastic biological systems with measured variability , 2014, Statistical applications in genetics and molecular biology.
[13] Markus Kollmann,et al. Quantifying origins of cell-to-cell variations in gene expression. , 2008, Biophysical journal.
[14] C. Gardiner. Handbook of Stochastic Methods , 1983 .
[15] D. Wallace,et al. Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease. , 2013, Cold Spring Harbor perspectives in biology.
[16] D. Balding,et al. Approximate Bayesian computation in population genetics. , 2002, Genetics.
[17] O. Shirihai,et al. Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. , 2008, Biochimica et biophysica acta.
[18] Paul Marjoram,et al. Markov chain Monte Carlo without likelihoods , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[19] D. Turnbull,et al. Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age. , 2001, American journal of human genetics.
[20] Iain G. Johnston,et al. Mitochondrial DNA disease and developmental implications for reproductive strategies , 2014, Molecular human reproduction.
[21] N. Camougrand,et al. Glutathione participates in the regulation of mitophagy in yeast , 2009, Autophagy.
[22] E. Shoubridge,et al. The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes , 2008, Nature Genetics.
[23] P. Chinnery,et al. Relaxed replication of mtDNA: A model with implications for the expression of disease. , 1999, American journal of human genetics.
[24] D. Gillespie. Exact Stochastic Simulation of Coupled Chemical Reactions , 1977 .
[25] C. Moraes,et al. Specific elimination of mutant mitochondrial genomes in patient–derived cells by mitoTALENs , 2013, Nature Medicine.
[26] Iain G. Johnston,et al. Mitochondrial Variability as a Source of Extrinsic Cellular Noise , 2011, PLoS Comput. Biol..
[27] H. Yonekawa,et al. New Evidence Confirms That the Mitochondrial Bottleneck Is Generated without Reduction of Mitochondrial DNA Content in Early Primordial Germ Cells of Mice , 2009, PLoS genetics.
[28] David C Samuels,et al. A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes , 2008, Nature Genetics.
[29] V. Macaulay,et al. Evidence from human oocytes for a genetic bottleneck in an mtDNA disease. , 1998, American journal of human genetics.
[30] D. Turnbull,et al. Mammalian mitochondrial genetics: heredity, heteroplasmy and disease. , 1997, Trends in genetics : TIG.
[31] A. Munnich,et al. Mutation dependance of the mitochondrial DNA copy number in the first stages of human embryogenesis. , 2013, Human molecular genetics.
[32] Jean-Pierre Mazat,et al. Mitochondrial threshold effects. , 2003, The Biochemical journal.
[33] A. M. van der Bliek,et al. Mitochondrial Fission, Fusion, and Stress , 2012, Science.
[34] Takahiko Hara,et al. The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells , 2007, Nature Genetics.
[35] O. Shirihai,et al. The interplay between mitochondrial dynamics and mitophagy. , 2011, Antioxidants & redox signaling.
[36] Suresh Kumar Poovathingal,et al. Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico , 2009, PLoS Comput. Biol..
[37] M Kimura,et al. SOLUTION OF A PROCESS OF RANDOM GENETIC DRIFT WITH A CONTINUOUS MODEL. , 1955, Proceedings of the National Academy of Sciences of the United States of America.
[38] A. Bredenoord,et al. Ooplasmic and nuclear transfer to prevent mitochondrial DNA disorders: conceptual and normative issues. , 2008, Human reproduction update.
[39] S. Mitalipov,et al. Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck. , 2012, Cell reports.
[40] David Welch,et al. Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems , 2009, Journal of The Royal Society Interface.
[41] D. Rand. THE UNITS OF SELECTION ON MITOCHONDRIAL DNA , 2001 .
[42] Iain G. Johnston,et al. Closed-form stochastic solutions for non-equilibrium dynamics and inheritance of cellular components over many cell divisions , 2015, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences.
[43] D. Wallace. Mitochondrial diseases in man and mouse. , 1999, Science.
[44] David C Samuels,et al. The distribution of mitochondrial DNA heteroplasmy due to random genetic drift. , 2008, American journal of human genetics.
[45] Carl T. Bergstrom,et al. Germline bottlenecks and the evolutionary maintenance of mitochondrial genomes. , 1998, Genetics.
[46] D. Chan,et al. Functions and dysfunctions of mitochondrial dynamics , 2007, Nature Reviews Molecular Cell Biology.
[47] O. Shirihai,et al. Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function. , 2009, Biophysical journal.
[48] B. Nelson,et al. Detection of heteroplasmy in individual mitochondrial particles , 2010, Analytical and bioanalytical chemistry.
[49] J. Lancaster,et al. Integration of cellular bioenergetics with mitochondrial quality control and autophagy , 2012, Biological chemistry.
[50] E. Schon,et al. Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation , 2008, The Journal of cell biology.
[51] S. Boissinot,et al. Evolutionary Biology , 2000, Evolutionary Biology.
[52] J. Drost,et al. Biological basis of germline mutation: Comparisons of spontaneous germline mutation rates among drosophila, mouse, and human , 1995, Environmental and molecular mutagenesis.
[53] Daniel J. White,et al. The Strength and Timing of the Mitochondrial Bottleneck in Salmon Suggests a Conserved Mechanism in Vertebrates , 2011, PloS one.
[54] D. Wells,et al. Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them , 2010, PLoS genetics.
[55] 张静,et al. Banana Ovate family protein MaOFP1 and MADS-box protein MuMADS1 antagonistically regulated banana fruit ripening , 2015 .
[56] J. Esplugues,et al. Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival‐promoting autophagy , 2011, Hepatology.
[57] P. Chinnery,et al. Reassessing evidence for a postnatal mitochondrial genetic bottleneck , 2010, Nature Genetics.
[58] Iain G. Johnston,et al. MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage. , 2014, Cell reports.
[59] W. Greene,et al. 计量经济分析 = Econometric analysis , 2009 .
[60] Patrick F Chinnery,et al. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease , 2010, Nature.
[61] E. Shoubridge,et al. Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA , 1996, Nature Genetics.
[62] E. Schon,et al. Mitophagy in cells with mtDNA mutations , 2012, Autophagy.
[63] C. Kukat,et al. mtDNA makes a U-turn for the mitochondrial nucleoid. , 2013, Trends in cell biology.
[64] Iain G. Johnston,et al. What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research , 2015, BioEssays : news and reviews in molecular, cellular and developmental biology.
[65] D. Egli,et al. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants , 2012, Nature.
[66] S. Mitalipov,et al. Towards germline gene therapy of inherited mitochondrial diseases , 2012, Nature.
[67] D. Bogenhagen. Mitochondrial DNA nucleoid structure. , 2012, Biochimica et biophysica acta.
[68] J. Nunnari,et al. Mitochondria: In Sickness and in Health , 2012, Cell.
[69] P. Chinnery,et al. Previous estimates of mitochondrial DNA mutation level variance did not account for sampling error: comparing the mtDNA genetic bottleneck in mice and humans. , 2010, American journal of human genetics.
[70] H. Coller,et al. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. , 1999, Nucleic acids research.
[71] K. Lawson,et al. Clonal analysis of the origin of primordial germ cells in the mouse. , 2007, Ciba Foundation symposium.
[72] S. Jakobs,et al. Super-resolution microscopy of mitochondria. , 2014, Current opinion in chemical biology.
[73] V. Beneš,et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. , 2009, Clinical chemistry.
[74] Daehee Hwang,et al. A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways , 2013, Science Signaling.
[75] D. Wells,et al. Preventing transmission of maternally inherited mitochondrial DNA diseases , 2009, BMJ : British Medical Journal.
[76] H. Jacobs,et al. No sex please, we're mitochondria: a hypothesis on the somatic unit of inheritance of mammalian mtDNA. , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.