The first 50 cases using a polycarbonate-urethane acetabular component in the TriboFit® Hip System for human hip reconstruction were reviewed. The average follow-up for cases not revised or deceased prior to 24 months was 28.0 months. The clinical results were similar to those reported in the literature for the same indications and follow-up. Therefore, with 2 to 4 years follow-up, it can be concluded that the TriboFit® Hip System is as safe and effective for use as a hip replacement system in femoral neck fracture patients as traditional hemiarthroplasty systems, and in osteoarthritis patients as a total hip system made of traditional bearing materials.