MTSS1 is a metastasis driver in a subset of human melanomas

[1]  Birgit Kasch,et al.  Next Generation , 2005, Im OP.

[2]  S. Wagner,et al.  An Attempt at a Molecular Prediction of Metastasis in Patients with Primary Cutaneous Melanoma , 2012, PloS one.

[3]  H. Kantarjian,et al.  Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management , 2012, American journal of hematology.

[4]  Brett W. Engelmann,et al.  SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome , 2012, Cell Communication and Signaling.

[5]  A. Sivachenko,et al.  A Landscape of Driver Mutations in Melanoma , 2012, Cell.

[6]  T. Fennell,et al.  Melanoma genome sequencing reveals frequent PREX2 mutations , 2012, Nature.

[7]  S. Nelson,et al.  Melanoma whole exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance , 2012, Nature Communications.

[8]  Robert A. Weinberg,et al.  Tumor Metastasis: Molecular Insights and Evolving Paradigms , 2011, Cell.

[9]  John C. Dawson,et al.  Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells , 2011, Oncogene.

[10]  Nikhil Wagle,et al.  Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  Gerald C. Chu,et al.  Proinvasion metastasis drivers in early-stage melanoma are oncogenes. , 2011, Cancer cell.

[12]  A. Ridley.  Life at the Leading Edge , 2011, Cell.

[13]  W. Jiang,et al.  The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance , 2011, Journal of Translational Medicine.

[14]  Y. Komiya,et al.  MIM regulates vertebrate neural tube closure , 2011, Development.

[15]  C. Moran,et al.  Importance of molecular features of non-small cell lung cancer for choice of treatment. , 2011, The American journal of pathology.

[16]  H. Fuchs,et al.  Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia , 2011, Journal of Cell Science.

[17]  Ning Zhang,et al.  Monitoring tumor metastases and osteolytic lesions with bioluminescence and micro CT imaging. , 2011, Journal of visualized experiments : JoVE.

[18]  J. Tenenbaum,et al.  A Melanoma Molecular Disease Model , 2011, PloS one.

[19]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[20]  N. Rosen,et al.  Resistance to BRAF inhibition in melanomas. , 2011, The New England journal of medicine.

[21]  Ute Curth,et al.  Molecular mechanism of Ena/VASP-mediated actin-filament elongation , 2011, The EMBO journal.

[22]  D. Pe’er,et al.  An Integrated Approach to Uncover Drivers of Cancer , 2010, Cell.

[23]  K. Flaherty,et al.  Inhibition of mutated, activated BRAF in metastatic melanoma. , 2010, The New England journal of medicine.

[24]  A. Oro,et al.  BAR domain competition during directional cellular migration , 2010, Cell cycle.

[25]  L. Chin,et al.  Integrative Genome Comparison of Primary and Metastatic Melanomas , 2010, PloS one.

[26]  A. Oro,et al.  I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration , 2010, The Journal of cell biology.

[27]  J. Bamburg,et al.  ADF/cofilin: a functional node in cell biology. , 2010, Trends in cell biology.

[28]  Derek Y. Chiang,et al.  The landscape of somatic copy-number alteration across human cancers , 2010, Nature.

[29]  Tom Royce,et al.  A comprehensive catalogue of somatic mutations from a human cancer genome , 2010, Nature.

[30]  W. Jiang,et al.  Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. , 2009, European journal of cancer.

[31]  P. Kinnunen,et al.  Molecular Mechanisms of Membrane Deformation by I-BAR Domain Proteins , 2009, Current Biology.

[32]  Wolfgang Alt,et al.  Image analysis of time-lapse movies—A precision control guided approach to correct motion artefacts , 2008, Journal of Neuroscience Methods.

[33]  J. Mesirov,et al.  Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases , 2008, Molecular Cancer Research.

[34]  A. D. Van den Abbeele,et al.  Major response to imatinib mesylate in KIT-mutated melanoma. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  Klemens Rottner,et al.  Arp2/3 complex interactions and actin network turnover in lamellipodia , 2008, The EMBO journal.

[36]  T. Golub,et al.  Modeling genomic diversity and tumor dependency in malignant melanoma. , 2008, Cancer research.

[37]  W. Hop,et al.  High-resolution array comparative genomic hybridization of chromosome 8q: evaluation of putative progression markers for gastroesophageal junction adenocarcinomas , 2007, Cytogenetic and Genome Research.

[38]  K. Schilling,et al.  Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells , 2007, BMC Developmental Biology.

[39]  K. Chan,et al.  Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma. , 2007, Human pathology.

[40]  John Condeelis,et al.  The cofilin pathway in breast cancer invasion and metastasis , 2007, Nature Reviews Cancer.

[41]  L. Machesky,et al.  MIM: a multifunctional scaffold protein , 2007, Journal of Molecular Medicine.

[42]  K. Ohashi,et al.  Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers , 2007, The Journal of cell biology.

[43]  A. Gotter,et al.  A palindrome-driven complex rearrangement of 22q11.2 and 8q24.1 elucidated using novel technologies. , 2007, Genome research.

[44]  Pekka Lappalainen,et al.  Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain–like mechanism , 2007, The Journal of cell biology.

[45]  L. Chin,et al.  Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene , 2006, Cell.

[46]  C. Collins,et al.  High‐resolution array comparative genomic hybridization of chromosome arm 8q: Evaluation of genetic progression markers for prostate cancer , 2005, Genes, chromosomes & cancer.

[47]  J. Fridlyand,et al.  Distinct sets of genetic alterations in melanoma. , 2005, The New England journal of medicine.

[48]  L. Machesky,et al.  Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B , 2005, Journal of Cell Science.

[49]  K. Pienta,et al.  Pathogenesis and treatment of prostate cancer bone metastases: targeting the lethal phenotype. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[50]  T. Golub,et al.  Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma , 2005, Nature.

[51]  N. Smith,et al.  Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein , 2005, Oncogene.

[52]  W. Gerald,et al.  Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. , 2005, The Journal of clinical investigation.

[53]  K. Pienta,et al.  Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines. , 2004, Cancer letters.

[54]  David I. Smith,et al.  Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma , 2003, Oncogene.

[55]  Pekka Lappalainen,et al.  Mouse MIM, a Tissue-specific Regulator of Cytoskeletal Dynamics, Interacts with ATP-Actin Monomers through Its C-terminal WH2 Domain* , 2003, The Journal of Biological Chemistry.

[56]  R. Hegde,et al.  Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane , 2003, The Journal of cell biology.

[57]  S. Narumiya,et al.  Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. , 1999, Science.

[58]  E. Nishida,et al.  Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization , 1998, Nature.

[59]  J. Parsons,et al.  Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation , 1997, Molecular and cellular biology.

[60]  Anne J. Ridley,et al.  The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.

[61]  Richard O. Hynes,et al.  Integrins: Versatility, modulation, and signaling in cell adhesion , 1992, Cell.

[62]  R. Gale,et al.  Chronic myeloid leukemia. , 1992, The American journal of medicine.

[63]  I. Fidler,et al.  A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. , 1984, Journal of the National Cancer Institute.

[64]  Marcel J T Reinders,et al.  Imaging , Diagnosis , Prognosis Clinical Cancer Research Integration of DNA Copy Number Alterations and Prognostic Gene Expression Signatures in Breast Cancer Patients , 2010 .

[65]  G. Barsh,et al.  Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi , 2010 .

[66]  J. Small,et al.  Correlated light and electron microscopy of the cytoskeleton. , 2008, Methods in cell biology.

[67]  K. Naresh,et al.  Altered melanoma cell surface glycosylation mediates organ specific adhesion and metastasis via lectin receptors on the lung vascular endothelium , 2005, Clinical & Experimental Metastasis.

[68]  E. Lander,et al.  A molecular signature of metastasis in primary solid tumors , 2003, Nature Genetics.

[69]  Kenneth J Pienta,et al.  MIM, a potential metastasis suppressor gene in bladder cancer. , 2002, Neoplasia.

[70]  D.,et al.  Regression Models and Life-Tables , 2022 .