Impaired brain growth and neurodevelopment in preterm infants with posthaemorrhagic ventricular dilatation

Aim:  To correlate volumetric magnetic resonance imaging at term with neurodevelopmental outcome at 2 years in infants with posthaemorrhagic ventricular dilatation. Preterm infants with posthaemorrhagic ventricular dilatation have high risk of disabilities, but the range is wide and predicting severity of motor and mental disability is difficult.

[1]  Deanne K. Thompson,et al.  Reduction in Cerebellar Volumes in Preterm Infants: Relationship to White Matter Injury and Neurodevelopment at Two Years of Age , 2006, Pediatric Research.

[2]  K. Yokochi,et al.  Thalamic lesions revealed by MR associated with periventricular leukomalacia and clinical profiles of subjects , 1997, Acta paediatrica.

[3]  Barbara J. Stoll,et al.  Neurodevelopmental Outcome of Extremely Low Birth Weight Infants With Posthemorrhagic Hydrocephalus Requiring Shunt Insertion , 2008, Pediatrics.

[4]  M. Blennow,et al.  Non-Protein-Bound Iron Is Elevated in Cerebrospinal Fluid from Preterm Infants with Posthemorrhagic Ventricular Dilatation , 2001, Pediatric Research.

[5]  J. Larroche.  Post-haemorrhagic hydrocephalus in infancy. Anatomical study. , 1972, Biology of the neonate.

[6]  R. Vannucci,et al.  Cerebral Oxidative Metabolism in Perinatal Post‐hemorrhagic Hydrocephalus , 1980, Developmental medicine and child neurology.

[7]  O. Saugstad,et al.  Increased hypoxanthine concentrations in cerebrospinal fluid of infants with hydrocephalus. , 1983, The Journal of pediatrics.

[8]  M W Davies,et al.  Reference ranges for the linear dimensions of the intracranial ventricles in preterm neonates , 2000, Archives of disease in childhood. Fetal and neonatal edition.

[9]  J. Allsop,et al.  Smaller cerebellar volumes in very preterm infants at term-equivalent age are associated with the presence of supratentorial lesions. , 2006, AJNR. American journal of neuroradiology.

[10]  Deanne K. Thompson,et al.  Head Growth in Preterm Infants: Correlation With Magnetic Resonance Imaging and Neurodevelopmental Outcome , 2008, Pediatrics.

[11]  M I Levene,et al.  Measurement of the growth of the lateral ventricles in preterm infants with real-time ultrasound. , 1981, Archives of disease in childhood.

[12]  N. Bayley.  Manual for the Bayley Scales of Infant Development , 1969 .

[13]  L. Sie,et al.  Early versus late treatment of posthaemorrhagic ventricular dilatation: results of a retrospective study from five neonatal intensive care units in The Netherlands , 2002, Acta paediatrica.

[14]  M. Blennow,et al.  Cytokine response in cerebrospinal fluid from preterm infants with posthaemorrhagic ventricular dilatation , 2002, Acta paediatrica.

[15]  A. Whitelaw,et al.  Differentiating developmental outcome between infants with severe disability in research studies: the role of Bayley Developmental Quotients. , 2011, The Journal of pediatrics.

[16]  R. Kikinis,et al.  Periventricular white matter injury in the premature infant is followed by reduced cerebral cortical gray matter volume at term , 1999, Annals of neurology.

[17]  H. Bassan.  Intracranial hemorrhage in the preterm infant: understanding it, preventing it. , 2009, Clinics in perinatology.

[18]  Colin Studholme,et al.  Differential effects of intraventricular hemorrhage and white matter injury on preterm cerebellar growth. , 2011, The Journal of pediatrics.

[19]  Richard L Robertson,et al.  Late Gestation Cerebellar Growth Is Rapid and Impeded by Premature Birth , 2005, Pediatrics.

[20]  J. Allsop,et al.  Quantification of Deep Gray Matter in Preterm Infants at Term-Equivalent Age Using Manual Volumetry of 3-Tesla Magnetic Resonance Images , 2007, Pediatrics.

[21]  Petronella Anbeek,et al.  Cerebellar volume and proton magnetic resonance spectroscopy at term, and neurodevelopment at 2 years of age in preterm infants , 2012, Developmental medicine and child neurology.

[22]  A. Whitelaw,et al.  Randomized Trial of Drainage, Irrigation and Fibrinolytic Therapy for Premature Infants with Posthemorrhagic Ventricular Dilatation: Developmental Outcome at 2 years , 2010, Pediatrics.

[23]  A. Whitelaw,et al.  Cerebrospinal fluid pressure during post haemorrhagic ventricular dilatation in newborn infants. , 1985, Archives of disease in childhood.

[24]  Núria Bargalló,et al.  Correlations of thalamic reductions with verbal fluency impairment in those born prematurely , 2006, Neuroreport.

[25]  T. Inder,et al.  Magnetic resonance imaging--insights into brain injury and outcomes in premature infants. , 2009, Journal of communication disorders.

[26]  Richard L Robertson,et al.  Impaired Trophic Interactions Between the Cerebellum and the Cerebrum Among Preterm Infants , 2005, Pediatrics.

[27]  A. C. Primavesi.  Neurologic and Developmental Disability after Extremely Preterm Birth , 2000 .

[28]  D. Prayer,et al.  Preterm birth and disruptive cerebellar development: assessment of perinatal risk factors. , 2008, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[29]  A. Edwards,et al.  Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy: a nested substudy of a randomised controlled trial , 2010, Lancet Neurology.

[30]  T. Baldeweg,et al.  Total brain white matter is a major determinant of IQ in adolescents born preterm , 2011, Annals of neurology.