No relationship between ovarian cancer risk and progesterone receptor gene polymorphism in a population-based, case-control study in North Carolina.

The protective effects of pregnancy and OC[3][1] use on ovarian cancer risk may be attributable to the action of progestins on the ovarian epithelium [(1)][2] . It has been hypothesized that a PROGINS is associated with increased risk of ovarian cancer. The PROGINS polymorphism has functional