Analysis and implementation of a fourth-order bandpass filter for R-wave detection of an implantable cardiac microstimulator

SUMMARY This paper presents an ultra-low-power fourth-order bandpass operational transconductance amplifier-C (OTA-C) filter for an implantable cardiac microstimulator used to detect the R-wave of intracardiac electrograms. The OTA-C filter fabricated by TSMC 0.35-µm complementary metal–oxide–semiconductor (CMOS) technology is operated in the subthreshold region to save power under a supply voltage of 1 V. The current cancellation technique is adopted to reduce the transconductance of the amplifier. Through this, the low-frequency OTA-C filter can be realized by ultra-low transconductance with on-chip capacitors. Direct comparison to conventional RLC ladders replaced by OTA-C circuits shows that the method of reducing the number of OTAs further diminishes power consumption. Design issues, including ultra-low transconductance, linearity, and noise, are also discussed. Measurement results show that the low-voltage, low-power filter has a bandwidth between 10 and 50 Hz, third inter-modulation distortion of −40 dB, dynamic range of 43 dB, and power consumption of only 12 nW. The real electrocardiography signal is fed into the bandpass filter to verify the function of signal processing with the distribution of the R-wave. Copyright © 2012 John Wiley & Sons, Ltd.

[1]  Barrie Gilbert,et al.  The multi-tanh principle: a tutorial overview , 1998, IEEE J. Solid State Circuits.

[2]  S. Sengupta Adaptively biased linear transconductor , 2005, IEEE Transactions on Circuits and Systems I: Regular Papers.

[3]  Franco Maloberti,et al.  A 60-dB dynamic-range CMOS sixth-order 2.4-Hz low-pass filter for medical applications , 2000 .

[4]  Ko-chi Kuo,et al.  A linear MOS transconductor using source degeneration and adaptive biasing , 2001 .

[5]  Andrea Baschirotto,et al.  A 1-/spl mu/A front end for pacemaker atrial sensing channels with early sensing capability , 2003, IEEE Transactions on Circuits and Systems II: Analog and Digital Signal Processing.

[6]  Shuenn-Yuh Lee,et al.  Systematic Design and Modeling of a OTA-C Filter for Portable ECG Detection , 2009, IEEE Transactions on Biomedical Circuits and Systems.

[7]  S.A.P. Haddad,et al.  The evolution of pacemakers , 2006, IEEE Engineering in Medicine and Biology Magazine.

[8]  L.S.Y. Wong,et al.  A very low-power CMOS mixed-signal IC for implantable pacemaker applications , 2004, IEEE Journal of Solid-State Circuits.

[9]  Edgar Sanchez-Sinencio,et al.  A CMOS transconductance amplifier architecture with wide tuning range for very low frequency applications , 2002 .

[10]  You-Yin Chen,et al.  A Programmable Implantable Microstimulator SoC With Wireless Telemetry: Application in Closed-Loop Endocardial Stimulation for Cardiac Pacemaker , 2011, IEEE Transactions on Biomedical Circuits and Systems.

[11]  E. Rodriguez-Villegas,et al.  A 1.25-V micropower Gm-C filter based on FGMOS transistors operating in weak inversion , 2004, IEEE Journal of Solid-State Circuits.

[12]  Esther Rodríguez-Villegas,et al.  A 60 pW g$_{m}$C Continuous Wavelet Transform Circuit for Portable EEG Systems , 2011, IEEE Journal of Solid-State Circuits.

[13]  E. Rodriguez-Villegas,et al.  A 1-V micropower log-domain integrator based on FGMOS transistors operating in weak inversion , 2004, IEEE Journal of Solid-State Circuits.

[14]  Esther Rodríguez-Villegas,et al.  A Nanopower Bandpass Filter for Detection of an Acoustic Signal in a Wearable Breathing Detector , 2007, IEEE Transactions on Biomedical Circuits and Systems.

[15]  Michiel Steyaert,et al.  A large-signal very low-distortion transconductor for high-frequency continuous-time filters , 1991 .

[16]  M. van de Gevel,et al.  Low-power MOS integrated filter with transconductors with spoilt current sources , 1997 .