The human immunodeficiency virus‐1 genotype diversity and drug resistance mutations profile of volunteer blood donors from Chinese blood centers

BACKGROUND: The global human immunodeficiency virus (HIV)‐1 epidemic is becoming increasingly diverse and complex. Molecular epidemiologic characteristics were studied for HIV‐1–infected blood donors from five Chinese regions to determine genotype diversity and drug resistance mutations (DRMs) profile.

[1]  P. Ghys,et al.  Global trends in molecular epidemiology of HIV-1 during 2000–2007 , 2011, AIDS.

[2]  Patrick M. High,et al.  Analysis of Chinese donors' return behavior , 2011, Transfusion.

[3]  Xinquan Wang,et al.  Genetic and Neutralization Sensitivity of Diverse HIV-1 env Clones from Chronically Infected Patients in China* , 2011, The Journal of Biological Chemistry.

[4]  J. Albert,et al.  Low prevalence of transmitted drug resistance among newly diagnosed HIV‐1 patients in Latvia , 2010, Journal of medical virology.

[5]  H. Xing,et al.  Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces. , 2010, AIDS research and human retroviruses.

[6]  W. Liu,et al.  Genetic characterization of 13 subtype CRF01_AE near full-length genomes in Guangxi, China. , 2010, AIDS research and human retroviruses.

[7]  C. Meade,et al.  Stress and Coping in HIV-Positive Former Plasma/Blood Donors in China: A Test of Cognitive Appraisal Theory , 2010, AIDS and Behavior.

[8]  S. Han,et al.  Comparison of genotypic resistance mutations in treatment-naive HIV type 1-infected patients in Korea and China. , 2010, AIDS research and human retroviruses.

[9]  Z. Bi,et al.  Surveillance of transmitted HIV type 1 drug resistance in newly diagnosed hiv type 1-infected patients in Shandong Province, China. , 2010, AIDS research and human retroviruses.

[10]  H. Xing,et al.  The Prevalence of Transmitted Antiretroviral Drug Resistance in Treatment-Naive HIV-Infected Individuals in China , 2010, Journal of acquired immune deficiency syndromes.

[11]  Zhe Wang,et al.  Human Immunodeficiency Virus Type 1 Subtypes Prevalence in Central China , 2009, Yonsei medical journal.

[12]  J. Li,et al.  Genetic diversity and drug resistance of HIV type 1 circulating recombinant Form_BC among drug users in Guangdong Province. , 2009, AIDS research and human retroviruses.

[13]  Yong-tang Zheng,et al.  Human immunodeficiency virus‐1 genotypic drug resistance among volunteer blood donors in Yunnan, China , 2009, Transfusion.

[14]  Oliver G Pybus,et al.  Phylodynamic analysis of the dissemination of HIV-1 CRF01_AE in Vietnam. , 2009, Virology.

[15]  Xiang He,et al.  Genetic and temporal dynamics of human immunodeficiency virus type 1 CRF07_BC in Xinjiang, China. , 2009, The Journal of general virology.

[16]  C. Brennan,et al.  Identification of human immunodeficiency virus type 1 non‐B subtypes and antiretroviral drug–resistant strains in United States blood donors , 2009, Transfusion.

[17]  O. Pybus,et al.  Temporal and Spatial Dynamics of Human Immunodeficiency Virus Type 1 Circulating Recombinant Forms 08_BC and 07_BC in Asia , 2008, Journal of Virology.

[18]  M. Peeters,et al.  Molecular tracing of sexual HIV Type 1 transmission in the southwest border of China. , 2008, AIDS research and human retroviruses.

[19]  D. Richman,et al.  Persistence of Transmitted Drug Resistance among Subjects with Primary Human Immunodeficiency Virus Infection , 2008, Journal of Virology.

[20]  Spread programme,et al.  Transmission of drug-resistant HIV-1 in Europe remains limited to single classes , 2008, AIDS.

[21]  O. Pybus,et al.  Chronology of the HIV-1 CRF07_BC expansion in East Asia , 2008, AIDS.

[22]  J. Haberer,et al.  The Chinese free antiretroviral treatment program: challenges and responses. , 2007, AIDS.

[23]  Longde Wang.  Overview of the HIV/AIDS epidemic, scientific research and government responses in China , 2007, AIDS.

[24]  H. Xing,et al.  Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China , 2007, AIDS.

[25]  H. Xing,et al.  Genotypic analysis of the protease and reverse transcriptase of HIV type 1 isolates from recently infected injecting drug users in western China. , 2007, AIDS research and human retroviruses.

[26]  H. Xing,et al.  Genetic diversity and drug resistance of human immunodeficiency virus type 1 (HIV-1) strains circulating in Shanghai. , 2007, AIDS research and human retroviruses.

[27]  M. Nei,et al.  MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. , 2007, Molecular biology and evolution.

[28]  Y. Takebe,et al.  Genotypic resistance mutations to antiretroviral drugs in treatment-naive HIV/AIDS patients living in Liaoning Province, China: baseline prevalence and subtype-specific difference. , 2007, AIDS research and human retroviruses.

[29]  H. Xing,et al.  Genotype and Phenotype Patterns of Drug-Resistant HIV-1 Subtype B′ (Thai B) Isolated From Patients Failing Antiretroviral Therapy in China , 2007, Journal of acquired immune deficiency syndromes.

[30]  Hong Li,et al.  Phenotypic resistance of resistant strains of HIV type‐1 subtype B in China , 2006, Chinese medical journal.

[31]  D. Ho,et al.  Dominance of HIV-1 Subtype CRF01_AE in Sexually Acquired Cases Leads to a New Epidemic in Yunnan Province of China , 2006, PLoS medicine.

[32]  P. Ghys,et al.  Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004 , 2006, AIDS.

[33]  H. Xing,et al.  Polymorphism of the protease and reverse transcriptase and drug resistance mutation patterns of HIV-1 subtype B prevailing in China. , 2006, Journal of acquired immune deficiency syndromes.

[34]  J. H. Chen,et al.  Clinical utility of genotyping resistance test on determining the mutation patterns in HIV-1 CRF01_AE and subtype B patients receiving antiretroviral therapy in Hong Kong. , 2006, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[35]  Michael P. Busch,et al.  Trends in Antiretroviral Drug Resistance and Clade Distributions Among HIV-1--Infected Blood Donors in Sao Paulo, Brazil , 2006, Journal of acquired immune deficiency syndromes.

[36]  Lynn Morris,et al.  Discordances between Interpretation Algorithms for Genotypic Resistance to Protease and Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Are Subtype Dependent , 2006, Antimicrobial Agents and Chemotherapy.

[37]  D. Ho,et al.  Molecular Characterization of Human Immunodeficiency Virus Type 1 and Hepatitis C Virus in Paid Blood Donors and Injection Drug Users in China , 2004, Journal of Virology.

[38]  H. Shan,et al.  Blood banking in China , 2002, The Lancet.

[39]  Jie Chen,et al.  Overland heroin trafficking routes and HIV-1 spread in south and south-east Asia , 2000, AIDS.

[40]  A. Telenti,et al.  HIV treatment failure: testing for HIV resistance in clinical practice. , 1998, Science.

[41]  C. Coyle.  How Providers Treat HIV: An Analysis of Provider Opinion and Adoption of the 2012 DHHS Guidelines for the use of Antiretroviral Agents in HIV-1 Infected Adults and Adolescents , 2013 .

[42]  Lin Yu-feng.  STUDY ABOUT HIV-1 SUBTYPES AMONG SEXUALLY TRANSMITTED HIV-1 CASES IN KUNMING , 2008 .

[43]  A. Fletcher,et al.  Young South Africans broadcast media and HIV / AIDS awareness: results of a national survey. , 2007 .

[44]  Cui Wei-guo.  Study on subtype and sequence of env gene among HIV-1 strain in Henan province , 2005 .

[45]  W. Zhe.  Study on subtype and sequence of the C_2-V_3 region of env gene among HIV-1 strains in Henan province , 2004 .

[46]  K. Hertogs,et al.  Genotypic and Phenotypic Evidence of Different Drug-Resistance Mutation Patterns between B and Non-B Subtype Isolates of Human Immunodeficiency Virus Type 1 found in Brazilian Patients Failing HAART , 2004, Virus Genes.

[47]  Douglas D. Richman,et al.  HIV chemotherapy , 2001, Nature.

[48]  Douglas D. Richman,et al.  HIV chemotherapy : AIDS , 2001 .