A systematic approach for establishing humane endpoints.

[1]  D. Morton.  Adverse Effects in Animals and their Relevance to Refining Scientific Procedures , 1990 .

[2]  D. Morton,et al.  The HID50 (hypothermia-inducing dose 50): an alternative to the LD50 for measurement of bacterial virulence. , 1992, International journal of experimental pathology.

[3]  L. V. Zutphen,et al.  Animal Alternatives, Welfare and Ethics , 1997 .

[4]  E. Welsh,et al.  Comparison of three methods used for assessment of pain in dogs. , 1998, Journal of the American Veterinary Medical Association.

[5]  R J Fielder,et al.  The international validation of a fixed-dose procedure as an alternative to the classical LD50 test. , 1990, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[6]  M. Deutsch,et al.  Time of death of CNS tumor-bearing rats can be reliably predicted by body weight-loss patterns. , 1991, Laboratory animal science.

[7]  D. M. Ryan,et al.  Guidelines for the welfare of animals in rodent protection tests: A Report from the Rodent Protection Test Working Party , 1994, Laboratory animals.

[8]  V. Baumans,et al.  Assessment of discomfort in gallstone-bearing mice: a practical example of the problems encountered in an attempt to recognize discomfort in laboratory animals , 1987, Laboratory animals.

[9]  M. Ullman-Cullere,et al.  Body condition scoring: a rapid and accurate method for assessing health status in mice. , 1999, Laboratory animal science.

[10]  David B. Morton,et al.  Humane endpoints in animal experiments for biomedical research , 1999 .

[11]  T. Jeneskog,et al.  Pain and distress in laboratory rodents and lagomorphs: Report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Pain and Distress accepted by the FELASA Board of Management November 1992 , 1994, Laboratory animals.

[12]  G. Ruggieri.  AQUATIC ANIMALS IN BIOMEDICAL RESEARCH , 1975, Annals of the New York Academy of Sciences.

[13]  L. Toth.  The moribund state as an experimental endpoint. , 1997, Contemporary topics in laboratory animal science.

[14]  D. Morton.  A fair press for animals. , 1992, New scientist.

[15]  P. H. Griffiths,et al.  Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment , 1985, Veterinary Record.

[16]  D. Brewster,et al.  Trends in cancer incidence and mortality in Scotland: description and possible explanations. , 1998, British Journal of Cancer.

[17]  T. Cole,et al.  Baby Check: a scoring system to grade the severity of acute systemic illness in babies under 6 months old. , 1991, Archives of disease in childhood.