EFEMP1 binds to STEAP1 to promote osteosarcoma proliferation and invasion via the Wnt/β-catenin and TGF-β/Smad2/3 signal pathways

[1]  Xiawei Wei,et al.  Targeting TGF-β signal transduction for fibrosis and cancer therapy , 2022, Molecular cancer.

[2]  Kewei Xiong,et al.  The Prognostic Value and Immunological Role of STEAP1 in Pan-Cancer: A Result of Data-Based Analysis , 2022, Oxidative medicine and cellular longevity.

[3]  P. Meltzer,et al.  New Horizons in the Treatment of Osteosarcoma. , 2021, The New England journal of medicine.

[4]  Wen-ting Lin,et al.  Regulatory Roles of Six-Transmembrane Epithelial Antigen of the Prostate Family Members in the Occurrence and Development of Malignant Tumors , 2021, Frontiers in Cell and Developmental Biology.

[5]  T. Dorff,et al.  Novel Redirected T–Cell Immunotherapies for Advanced Prostate Cancer , 2021, Clinical cancer research : an official journal of the American Association for Cancer Research.

[6]  Zairan Wang,et al.  Predictive potential of STEAP family for survival, immune microenvironment and therapy response in glioma. , 2021, International immunopharmacology.

[7]  Hong-fen Guo,et al.  Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy , 2021, Journal for ImmunoTherapy of Cancer.

[8]  S. Peng,et al.  Fusion Protein Vaccine Based on Ag85B and STEAP1 Induces a Protective Immune Response against Prostate Cancer , 2021, Vaccines.

[9]  C. Riganti,et al.  Drug Resistance in Osteosarcoma: Emerging Biomarkers, Therapeutic Targets and Treatment Strategies , 2021, Cancers.

[10]  M. Batish,et al.  Identification of a New Transcriptional Co-Regulator of STEAP1 in Ewing’s Sarcoma , 2021, Cells.

[11]  R. Montironi,et al.  Treating Prostate Cancer by Antibody–Drug Conjugates , 2021, International journal of molecular sciences.

[12]  Zhe Zhang,et al.  A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos , 2020, Journal of cellular and molecular medicine.

[13]  N. Herold,et al.  Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies , 2020, International journal of molecular sciences.

[14]  Jing Liu,et al.  The Tumor Suppressive Roles and Prognostic Values of STEAP Family Members in Breast Cancer , 2020, BioMed research international.

[15]  D. Busch,et al.  MHC Class I-Restricted TCR-Transgenic CD4+ T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo , 2020, Cells.

[16]  Tiantian Wang,et al.  Six-transmembrane epithelial antigen of the prostate 1 expression promotes ovarian cancer metastasis by aiding progression of epithelial-to-mesenchymal transition , 2020, Histochemistry and Cell Biology.

[17]  Yi-Hong Zhou,et al.  Dual antivascular function of human fibulin‐3 variant, a potential new drug discovery strategy for glioblastoma , 2020, Cancer science.

[18]  H. Scher,et al.  Phase I Study of DSTP3086S, an Antibody-Drug Conjugate Targeting Six-Transmembrane Epithelial Antigen of Prostate 1, in Metastatic Castration-Resistant Prostate Cancer. , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  Serge K. Lyashchenko,et al.  Imaging Patients with Metastatic Castration-Resistant Prostate Cancer Using 89Zr-DFO-MSTP2109A Anti-STEAP1 Antibody , 2019, The Journal of Nuclear Medicine.

[20]  Jiali Sun,et al.  Six‐transmembrane epithelial antigen of the prostate 1 is associated with tumor invasion and migration in endometrial carcinomas , 2019, Journal of cellular biochemistry.

[21]  Jiali Sun,et al.  STEAP1 Inhibits Breast Cancer Metastasis and Is Associated With Epithelial–Mesenchymal Transition Procession , 2019, Clinical breast cancer.

[22]  F. Verrecchia,et al.  Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment , 2018, Front. Oncol..

[23]  E. Chiocca,et al.  Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma , 2017, Clinical Cancer Research.

[24]  Dong Zhang,et al.  Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/β-catenin signaling pathway , 2017, Scientific Reports.

[25]  M. Viapiano,et al.  Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment , 2017 .

[26]  Qiang Wang,et al.  EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway , 2016, Oncotarget.

[27]  X. Wan,et al.  EFEMP1 is repressed by estrogen and inhibits the epithelial-mesenchymal transition via Wnt/β-catenin signaling in endometrial carcinoma , 2016, Oncotarget.

[28]  Michael L. Gatza,et al.  Fibulin-3 is a Novel TGF-β pathway Inhibitor in the Breast Cancer Microenvironment , 2015, Oncogene.

[29]  X. Wan,et al.  Epigenetic Inactivation of EFEMP1 Is Associated with Tumor Suppressive Function in Endometrial Carcinoma , 2013, PloS one.

[30]  G. Nuovo,et al.  Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling. , 2012, Cancer research.

[31]  H. Blum,et al.  EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells , 2009, Biological chemistry.

[32]  R. Hubert,et al.  STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors. , 1999, Proceedings of the National Academy of Sciences of the United States of America.