Advances of flexible pressure sensors toward artificial intelligence and health care applications

By virtue of their wide applications in personal electronic devices and industrial monitoring, pressure sensors are attractive candidates for promoting the advancement of science and technology in modern society. Flexible pressure sensors based on organic materials, which combine unique advantages of flexibility and low-cost, have emerged as a highly active field due to their promising applications in artificial intelligence systems and wearable health care devices. In this review, we focus on the fundamentals of flexible pressure sensors, and subsequently on several critical concepts for the exploration of functional materials and optimization of sensing devices toward practical applications. Perspectives on self-powered, transparent and implantable pressure sensing devices are also examined to highlight the development directions in this exciting research field.

[1]  Yonggang Huang,et al.  High performance piezoelectric devices based on aligned arrays of nanofibers of poly(vinylidenefluoride-co-trifluoroethylene) , 2013, Nature Communications.

[2]  Zhibin Yu,et al.  User-interactive electronic skin for instantaneous pressure visualization. , 2013, Nature materials.

[3]  Jing Xu,et al.  Growth of Directly Transferable In2O3 Nanowire Mats for Transparent Thin‐film Transistor Applications , 2011, Advanced materials.

[4]  C. Zhang,et al.  Graphene based piezoresistive pressure sensor , 2013 .

[5]  E. Laukhina,et al.  Ultrasensitive Piezoresistive All‐Organic Flexible Thin Films , 2010, Advanced materials.

[6]  Meifang Zhu,et al.  Highly Conductive, Flexible, and Compressible All‐Graphene Passive Electronic Skin for Sensing Human Touch , 2014, Advanced materials.

[7]  Kiwoong Kim,et al.  Carbon Nanotube and Graphene Hybrid Thin Film for Transparent Electrodes and Field Effect Transistors , 2014, Advanced materials.

[8]  Sigurd Wagner,et al.  Flexible membrane pressure sensor , 2005 .

[9]  S. Bauer,et al.  Organic Nonvolatile Memory Transistors for Flexible Sensor Arrays , 2009, Science.

[10]  M. Islam,et al.  3D‐Transistor Array Based on Horizontally Suspended Silicon Nano‐bridges Grown via a Bottom‐Up Technique , 2014, Advanced materials.

[11]  Zach DeVito,et al.  Opt , 2017 .

[12]  Zhong Lin Wang,et al.  Taxel-Addressable Matrix of Vertical-Nanowire Piezotronic Transistors for Active and Adaptive Tactile Imaging , 2013, Science.

[13]  Lori Shutter,et al.  Dual-mode operation of flexible piezoelectric polymer diaphragm for intracranial pressure measurement , 2010 .

[14]  Tushar Sharma,et al.  Patterning piezoelectric thin film PVDF–TrFE based pressure sensor for catheter application , 2012 .

[15]  Shin-Tson Wu,et al.  Rollable multicolor display using electrically induced blueshift of a cholesteric reactive mesogen mixture , 2006 .

[16]  Yonggang Huang,et al.  Conformable amplified lead zirconate titanate sensors with enhanced piezoelectric response for cutaneous pressure monitoring , 2014, Nature Communications.

[17]  Xuewen Wang,et al.  Silk‐Molded Flexible, Ultrasensitive, and Highly Stable Electronic Skin for Monitoring Human Physiological Signals , 2014, Advanced materials.

[18]  Nae-Eung Lee,et al.  Transparent and flexible organic field-effect transistor for multi-modal sensing , 2012 .

[19]  Jin-Woo Han,et al.  Flexible, compressible, hydrophobic, floatable, and conductive carbon nanotube-polymer sponge , 2013 .

[20]  Liyong Niu,et al.  Photosensitive Graphene Transistors , 2014, Advanced materials.

[21]  Yu-Cheng Lin,et al.  Flexible Electronics Sensors for Tactile Multi-Touching , 2009, Sensors.

[22]  V. Maheshwari,et al.  High-Resolution Thin-Film Device to Sense Texture by Touch , 2006, Science.

[23]  Zhong‐Lin Wang,et al.  Progress in Piezotronics and Piezo‐Phototronics , 2012, Advanced materials.

[24]  G. Tröster,et al.  Wafer-scale design of lightweight and transparent electronics that wraps around hairs , 2014, Nature Communications.

[25]  C. Keplinger,et al.  Flexible ferroelectret field-effect transistor for large-area sensor skins and microphones , 2006 .

[26]  Jonathan A. Fan,et al.  Materials and Designs for Wireless Epidermal Sensors of Hydration and Strain , 2014 .

[27]  Benjamin C. K. Tee,et al.  An electrically and mechanically self-healing composite with pressure- and flexion-sensitive properties for electronic skin applications. , 2012, Nature nanotechnology.

[28]  Zhong Lin Wang,et al.  Self-powered nanowire devices. , 2010, Nature nanotechnology.

[29]  T. Trung,et al.  A Flexible Bimodal Sensor Array for Simultaneous Sensing of Pressure and Temperature , 2014, Advanced materials.

[30]  U. Chung,et al.  Highly Stretchable Resistive Pressure Sensors Using a Conductive Elastomeric Composite on a Micropyramid Array , 2014, Advanced materials.

[31]  S. Bauer,et al.  Flexible active-matrix cells with selectively poled bifunctional polymer-ceramic nanocomposite for pressure and temperature sensing skin , 2009 .

[32]  Gui Yu,et al.  Functional Organic Field‐Effect Transistors , 2010, Advanced materials.

[33]  Wondong Kim,et al.  Thermoelectric imaging of structural disorder in epitaxial graphene. , 2013, Nature materials.

[34]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[35]  Chen Li,et al.  A High Temperature Capacitive Pressure Sensor Based on Alumina Ceramic for in Situ Measurement at 600 °C , 2014, Sensors.

[36]  R. Fagard Exercise characteristics and the blood pressure response to dynamic physical training. , 2001, Medicine and science in sports and exercise.

[37]  Takao Someya,et al.  Ultrathin, highly flexible and stretchable PLEDs , 2013, Nature Photonics.

[38]  Xavier Monnet,et al.  Contribution of arterial stiffness and stroke volume to peripheral pulse pressure in ICU patients: an arterial tonometry study , 2007, Intensive Care Medicine.

[39]  Spyros G. Tzafestas,et al.  Analysis and design of a new piezoresistive tactile sensor system for robotic applications , 1994, J. Intell. Robotic Syst..

[40]  K. Müllen,et al.  Graphene as Transparent Electrode Material for Organic Electronics , 2011, Advanced materials.

[41]  T. Someya,et al.  Flexible organic transistors and circuits with extreme bending stability. , 2010, Nature materials.

[42]  S. Bauer,et al.  Materials for stretchable electronics , 2012 .

[43]  M. Berggren,et al.  Electrocardiographic Recording with Conformable Organic Electrochemical Transistor Fabricated on Resorbable Bioscaffold , 2014, Advanced materials.

[44]  Daniel M. Vogt,et al.  Embedded 3D Printing of Strain Sensors within Highly Stretchable Elastomers , 2014, Advanced materials.

[45]  Ki-Uk Kyung,et al.  Polymer‐Waveguide‐Based Flexible Tactile Sensor Array for Dynamic Response , 2014, Advanced materials.

[46]  Sung-hoon Ahn,et al.  A flexible and highly sensitive strain-gauge sensor using reversible interlocking of nanofibres. , 2012, Nature materials.

[47]  Daoben Zhu,et al.  Interface engineering: an effective approach toward high-performance organic field-effect transistors. , 2009, Accounts of chemical research.

[48]  Tao Han,et al.  A high-sensitivity pressure sensor based on surface transverse wave , 2012 .

[49]  S. Bauer,et al.  Flexible large area ferroelectret sensors for location sensitive touchpads , 2008 .

[50]  Zhong Lin Wang,et al.  Piezoelectric nanogenerator using p-type ZnO nanowire arrays. , 2009, Nano letters.

[51]  Andrew G. Gillies,et al.  Nanowire active-matrix circuitry for low-voltage macroscale artificial skin. , 2010, Nature materials.

[52]  M. Knite,et al.  Polyisoprene-carbon black nanocomposites as tensile strain and pressure sensor materials , 2004 .

[53]  Long Lin,et al.  A Nanogenerator for Energy Harvesting from a Rotating Tire and its Application as a Self‐Powered Pressure/Speed Sensor , 2011, Advanced materials.

[54]  Marius Grundmann,et al.  Recent Progress on ZnO‐Based Metal‐Semiconductor Field‐Effect Transistors and Their Application in Transparent Integrated Circuits , 2010, Advanced materials.

[55]  R. Collins,et al.  Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled tri , 2005, The Lancet.

[56]  Zhong Lin Wang,et al.  Piezoelectric field effect transistor and nanoforce sensor based on a single ZnO nanowire. , 2006, Nano letters.

[57]  Kilwon Cho,et al.  Water‐Free Transfer Method for CVD‐Grown Graphene and Its Application to Flexible Air‐Stable Graphene Transistors , 2014, Advanced materials.

[58]  T. Someya,et al.  Stretchable active-matrix organic light-emitting diode display using printable elastic conductors. , 2009, Nature materials.

[59]  John C. Roberts,et al.  Capacitance pressure sensor based on GaN high-electron-mobility transistor-on-Si membrane , 2005 .

[60]  Pooi See Lee,et al.  Highly Stretchable Piezoresistive Graphene–Nanocellulose Nanopaper for Strain Sensors , 2014, Advanced materials.

[61]  W. Marsden I and J , 2012 .

[62]  Takao Someya,et al.  A large-area, flexible pressure sensor matrix with organic field-effect transistors for artificial skin applications. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[63]  Hao Zhang,et al.  Temperature-independent FBG pressure sensor with high sensitivity , 2007 .

[64]  Shuhong Yu,et al.  A Flexible and Highly Pressure‐Sensitive Graphene–Polyurethane Sponge Based on Fractured Microstructure Design , 2013, Advanced materials.

[65]  Chang Kyu Jeong,et al.  Highly‐Efficient, Flexible Piezoelectric PZT Thin Film Nanogenerator on Plastic Substrates , 2014, Advanced materials.

[66]  Yong-Young Noh,et al.  Large-scale organic nanowire lithography and electronics , 2013, Nature Communications.

[67]  Zhong Lin Wang,et al.  Triboelectric active sensor array for self-powered static and dynamic pressure detection and tactile imaging. , 2013, ACS nano.

[68]  Daoben Zhu,et al.  Multi‐Functional Integration of Organic Field‐Effect Transistors (OFETs): Advances and Perspectives , 2013, Advanced materials.

[69]  Do Hwan Kim,et al.  Transparent, Low‐Power Pressure Sensor Matrix Based on Coplanar‐Gate Graphene Transistors , 2014, Advanced materials.

[70]  A. Javey,et al.  Toward the Development of Printable Nanowire Electronics and Sensors , 2009 .

[71]  Chih-Cheng Chang,et al.  An Enhanced Sensing Application Based on a Flexible Projected Capacitive-Sensing Mattress , 2014, Sensors.

[72]  Vladimir V Tsukruk,et al.  Freely suspended nanocomposite membranes as highly sensitive sensors , 2004, Nature materials.

[73]  Takao Someya,et al.  Organic-transistor-based flexible pressure sensors using ink-jet-printed electrodes and gate dielectric layers , 2006 .

[74]  Benjamin C. K. Tee,et al.  Flexible polymer transistors with high pressure sensitivity for application in electronic skin and health monitoring , 2013, Nature Communications.

[75]  Sang-Hoon Lee,et al.  CNT/PDMS Composite Flexible Dry Electrodesfor Long-Term ECG Monitoring , 2012, IEEE Transactions on Biomedical Engineering.

[76]  Benjamin C. K. Tee,et al.  Skin-like pressure and strain sensors based on transparent elastic films of carbon nanotubes. , 2011, Nature nanotechnology.

[77]  M. Kaltenbrunner,et al.  Ultrathin and lightweight organic solar cells with high flexibility , 2012, Nature Communications.

[78]  Andrew G. Glen,et al.  APPL , 2001 .

[79]  G. Bray,et al.  Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet , 2001 .

[80]  J. Feely,et al.  Favourable effects on arterial wave reflection and pulse pressure amplification of adding angiotensin II receptor blockade in resistant hypertension , 2000, Journal of Human Hypertension.

[81]  T. Someya,et al.  Conformable, flexible, large-area networks of pressure and thermal sensors with organic transistor active matrixes. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[82]  Xiaodong Xu,et al.  Systematic Doping Control of CVD Graphene Transistors with Functionalized Aromatic Self‐Assembled Monolayers , 2014 .

[84]  Weiguang Xie,et al.  Graphene Based Non‐Volatile Memory Devices , 2014, Advanced materials.

[85]  K. Najafi,et al.  A wireless batch sealed absolute capacitive pressure sensor , 2001 .

[86]  Werner Karl Schomburg,et al.  Pressure sensor from a PVDF film , 2008 .

[87]  R. Dauskardt,et al.  An ultra-sensitive resistive pressure sensor based on hollow-sphere microstructure induced elasticity in conducting polymer film , 2014, Nature Communications.

[88]  Lai-Peng Ma,et al.  25th Anniversary Article: Carbon Nanotube‐ and Graphene‐Based Transparent Conductive Films for Optoelectronic Devices , 2014, Advanced materials.

[89]  T. Someya,et al.  Organic transistors with high thermal stability for medical applications , 2012, Nature Communications.

[90]  Lei Zhang,et al.  Inkjet Printing Short‐Channel Polymer Transistors with High‐Performance and Ultrahigh Photoresponsivity , 2014, Advanced materials.

[91]  T. Someya,et al.  A Rubberlike Stretchable Active Matrix Using Elastic Conductors , 2008, Science.

[92]  G. Gelinck,et al.  Flexible active-matrix displays and shift registers based on solution-processed organic transistors , 2004, Nature materials.

[93]  Benjamin C. K. Tee,et al.  Highly sensitive flexible pressure sensors with microstructured rubber dielectric layers. , 2010, Nature materials.

[94]  Jun Liu,et al.  Influence of corneal biomechanical properties on intraocular pressure measurement: Quantitative analysis , 2005, Journal of cataract and refractive surgery.

[95]  T. Someya,et al.  Stretchable, Large‐area Organic Electronics , 2010, Advanced materials.

[96]  Vincenzo Palermo,et al.  Leveraging the Ambipolar Transport in Polymeric Field‐Effect Transistors via Blending with Liquid‐Phase Exfoliated Graphene , 2014, Advanced materials.

[97]  Benjamin C. K. Tee,et al.  25th Anniversary Article: The Evolution of Electronic Skin (E‐Skin): A Brief History, Design Considerations, and Recent Progress , 2013, Advanced materials.

[98]  Abhay B. Joshi,et al.  Simulations of piezoelectric pressure sensor for radial artery pulse measurement , 2010 .

[99]  Wen-Hung Huang,et al.  Acute reversible changes of brachial-ankle pulse wave velocity in children with acute poststreptococcal glomerulonephritis , 2011, Pediatric Nephrology.

[100]  Yaping Zang,et al.  Specific and Reproducible Gas Sensors Utilizing Gas‐Phase Chemical Reaction on Organic Transistors , 2014, Advanced materials.

[101]  Zhong Lin Wang,et al.  Flexible piezotronic strain sensor. , 2008, Nano letters.

[102]  B. Shirinzadeh,et al.  A wearable and highly sensitive pressure sensor with ultrathin gold nanowires , 2014, Nature Communications.

[103]  M. Kaltenbrunner,et al.  Mechanically Adaptive Organic Transistors for Implantable Electronics , 2014, Advanced materials.

[104]  I. Manunza,et al.  Pressure sensing using a completely flexible organic transistor. , 2007, Biosensors & bioelectronics.

[105]  Dan Li,et al.  Solvated Graphenes: An Emerging Class of Functional Soft Materials , 2013, Advanced materials.

[106]  Zhiyong Fan,et al.  Scalable Integration of Indium Zinc Oxide/Photosensitive‐Nanowire Composite Thin‐Film Transistors for Transparent Multicolor Photodetectors Array , 2014, Advanced materials.

[107]  Ji Hoon Kim,et al.  Reverse‐Micelle‐Induced Porous Pressure‐Sensitive Rubber for Wearable Human–Machine Interfaces , 2014, Advanced materials.

[108]  John A. Rogers,et al.  An analytical study of two-dimensional buckling of thin films on compliant substrates , 2008 .

[109]  Dingchang Zheng,et al.  Non-invasive quantification of peripheral arterial volume distensibility and its non-linear relationship with arterial pressure. , 2009, Journal of biomechanics.

[110]  Byeong-Soo Bae,et al.  Rollable Transparent Glass‐Fabric Reinforced Composite Substrate for Flexible Devices , 2010, Advances in Materials.

[111]  Zhong Lin Wang,et al.  Air/Liquid‐Pressure and Heartbeat‐Driven Flexible Fiber Nanogenerators as a Micro/Nano‐Power Source or Diagnostic Sensor , 2011, Advanced materials.

[112]  Yonggang Huang,et al.  Materials and Mechanics for Stretchable Electronics , 2010, Science.

[113]  Benjamin C. K. Tee,et al.  Transparent, Optical, Pressure‐Sensitive Artificial Skin for Large‐Area Stretchable Electronics , 2012, Advanced materials.

[114]  S. Nam,et al.  Highly Sensitive Non‐Classical Strain Gauge Using Organic Heptazole Thin‐Film Transistor Circuit on a Flexible Substrate , 2014 .

[115]  Yoseph Rozenman,et al.  Wireless acoustic communication with a miniature pressure sensor in the pulmonary artery for disease surveillance and therapy of patients with congestive heart failure. , 2007, Journal of the American College of Cardiology.

[116]  Zhong Lin Wang,et al.  Radial-arrayed rotary electrification for high performance triboelectric generator , 2014, Nature Communications.

[117]  In-Byeong Kang,et al.  Flexible Display Technology – Opportunity and Challenges to New Business Application , 2009 .

[118]  V. R. Raju,et al.  Paper-like electronic displays: Large-area rubber-stamped plastic sheets of electronics and microencapsulated electrophoretic inks , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[119]  Coskun Kocabas,et al.  Gate-tunable photoemission from graphene transistors. , 2014, Nano letters.

[120]  Sanat S Bhole,et al.  Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin , 2014, Science.

[121]  Tse Nga Ng,et al.  Highly sensitive tactile sensors integrated with organic transistors , 2012 .

[122]  M. Kaltenbrunner,et al.  An ultra-lightweight design for imperceptible plastic electronics , 2013, Nature.