Various ground systems belonging to ESA ground segments rely on configuration data which are prepared offline with a database management application. This is a common practice for different generic systems, which are customized for a particular mission through the population of a configuration database. Different applications have been developed in the past for preparing and managing the configuration data needed by these systems, each targeted to a different system and/or mission. DABYS is a new generic system dedicated to the management of mission and application configuration data, which standardizes and harmonizes the software used for this specific purpose and the associated operations. It is in particular used for the preparation and management of the operational TM/TC database of ESA missions.