Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes
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V. Rinne | J. Hakkola | R. Wiesner | P. Tavi | B. Finck | A. Franko | Mikko Karpale | Outi Kummu | Maija Mutikainen | M. Buler | Kari T. Chambers | Sanna-Mari Aatsinki | Mahmoud-Sobhy Elkhwanky | P. Viitala | Sanna‐Mari Aatsinki
[1] D. Kiel,et al. Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. , 2018, American journal of human genetics.
[2] N. Napoli,et al. Vitamin D and Diabetes Mellitus. , 2018, Frontiers of hormone research.
[3] P. O’Reilly,et al. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels , 2018, Nature Communications.
[4] S. Virtanen,et al. Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity , 2017, Diabetes.
[5] M. Levine,et al. CYP2R1 mutations causing vitamin D-deficiency rickets , 2017, The Journal of Steroid Biochemistry and Molecular Biology.
[6] Glenville Jones,et al. Vitamin D–Dependent Rickets Type 1B (25‐Hydroxylase Deficiency): A Rare Condition or a Misdiagnosed Condition? , 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[7] Michael F. Holick,et al. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention , 2017, Reviews in Endocrine and Metabolic Disorders.
[8] Zhan Yin,et al. Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)2D3. , 2017, Cell reports.
[9] I. Goldstein,et al. Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response. , 2017, Genome research.
[10] M. Abbas. Physiological functions of Vitamin D in adipose tissue , 2017, The Journal of Steroid Biochemistry and Molecular Biology.
[11] Tao Liu,et al. Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse , 2016, Nucleic Acids Res..
[12] Fabin Dang,et al. Fasting and Feeding Signals Control the Oscillatory Expression of Angptl8 to Modulate Lipid Metabolism , 2016, Scientific Reports.
[13] Gerhard K. H. Przemeck,et al. Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice , 2016, Diabetes.
[14] H. Duan,et al. PGC-1α, glucose metabolism and type 2 diabetes mellitus. , 2016, The Journal of endocrinology.
[15] P. Dhawan,et al. Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects. , 2016, Physiological reviews.
[16] Kyoung-Jae Won,et al. Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo , 2015, Genome research.
[17] M. Levine,et al. CYP2R1 Mutations Impair Generation of 25-hydroxyvitamin D and Cause an Atypical Form of Vitamin D Deficiency. , 2015, The Journal of clinical endocrinology and metabolism.
[18] A. Prentice,et al. 25(OH)D2 Half-Life Is Shorter Than 25(OH)D3 Half-Life and Is Influenced by DBP Concentration and Genotype , 2014, The Journal of clinical endocrinology and metabolism.
[19] M. D. de Angelis,et al. Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. , 2014, Journal of hepatology.
[20] B. Zinman,et al. Prospective association of 25(OH)D with metabolic syndrome , 2014, Clinical endocrinology.
[21] J. Auwerx,et al. Vitamin D and energy homeostasis—of mice and men , 2014, Nature Reviews Endocrinology.
[22] C. Mathieu,et al. Vitamin D and diabetes: the odd couple , 2013, Trends in Endocrinology & Metabolism.
[23] H. DeLuca,et al. CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo , 2013, Proceedings of the National Academy of Sciences.
[24] S. Burgess,et al. Liver-Specific PGC-1beta Deficiency Leads to Impaired Mitochondrial Function and Lipogenic Response to Fasting-Refeeding , 2012, PloS one.
[25] Michael Snyder,et al. A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells , 2012, Genome research.
[26] D. Russell,et al. Mutation of the CYP2R1 vitamin D 25-hydroxylase in a Saudi Arabian family with severe vitamin D deficiency. , 2012, The Journal of clinical endocrinology and metabolism.
[27] H. DeLuca,et al. Vitamin D 25-hydroxylase - Four decades of searching, are we there yet? , 2012, Archives of biochemistry and biophysics.
[28] Glenville Jones,et al. 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D. , 2012, Archives of biochemistry and biophysics.
[29] JoAnn E Manson,et al. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. , 2012, Endocrine reviews.
[30] S. Kersten,et al. Energy-sensing Factors Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator 1-α (PGC-1α) and AMP-activated Protein Kinase Control Expression of Inflammatory Mediators in Liver , 2011, The Journal of Biological Chemistry.
[31] M. Melamed,et al. Association of glucocorticoid use and low 25-hydroxyvitamin D levels: results from the National Health and Nutrition Examination Survey (NHANES): 2001-2006. , 2011, The Journal of clinical endocrinology and metabolism.
[32] T. Spector,et al. Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes , 2011, Diabetes.
[33] I. Schuster. Cytochromes P450 are essential players in the vitamin D signaling system. , 2011, Biochimica et biophysica acta.
[34] J. Chou,et al. Sexually Dimorphic Actions of Glucocorticoids Provide a Link to Inflammatory Diseases with Gender Differences in Prevalence , 2010, Science Signaling.
[35] Daniel L. Koller,et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study , 2010, The Lancet.
[36] J. Hakkola,et al. Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver. , 2010, Chemical research in toxicology.
[37] Michelle Chan,et al. Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue. , 2009, Endocrinology.
[38] Satu Arpiainen,et al. Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes. , 2008, Toxicology and applied pharmacology.
[39] C. Zechner,et al. Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. , 2008, Genes & development.
[40] K. Badenhoop,et al. CYP2R1 (vitamin D 25‐hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans , 2007, Diabetes/metabolism research and reviews.
[41] E. Lobenhofer,et al. Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. , 2006, Molecular cell.
[42] R. Savkur,et al. Coactivation of the Human Vitamin D Receptor by the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 α , 2005, Molecular Pharmacology.
[43] Thomas Werner,et al. MatInspector and beyond: promoter analysis based on transcription factor binding sites , 2005, Bioinform..
[44] R. Savkur,et al. Coactivation of the human vitamin D receptor by the peroxisome proliferator-activated receptor gamma coactivator-1 alpha. , 2005, Molecular pharmacology.
[45] Glenville Jones,et al. Enzymes involved in the activation and inactivation of vitamin D. , 2004, Trends in biochemical sciences.
[46] Jiandie D. Lin,et al. Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice , 2004, Cell.
[47] C. Kellendonk,et al. Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. , 2004, Molecular endocrinology.
[48] Jeffrey B. Cheng,et al. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[49] Anastasia Kralli,et al. The Transcriptional Coactivator PGC-1 Regulates the Expression and Activity of the Orphan Nuclear Receptor Estrogen-Related Receptor α (ERRα)* , 2003, The Journal of Biological Chemistry.
[50] D. Knutti,et al. The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). , 2003, The Journal of biological chemistry.
[51] Guillaume Adelmant,et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 , 2001, Nature.
[52] I. Björkhem,et al. Short-term starvation increases calcidiol-24-hydroxylase activity and mRNA level in rat kidney. , 1994, European journal of endocrinology.
[53] M. Ståhlberg,et al. Immunochemical detection of human liver cytochrome P450 forms related to phenobarbital-inducible forms in the mouse. , 1990, Biochemical pharmacology.
[54] W. Rutter,et al. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. , 1979, Biochemistry.