Microglia in neurodegenerative disease

[1]  J. Clarke,et al.  What is a systematic review? , 2011, Evidence Based Nursing.

[2]  F. Heppner,et al.  Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia , 2009, Nature Neuroscience.

[3]  J. Suttles,et al.  Functional plasticity of macrophages: in situ reprogramming of tumor‐associated macrophages , 2009, Journal of leukocyte biology.

[4]  V. Perry,et al.  Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping. , 2009, The American journal of pathology.

[5]  L. Kiemeney,et al.  Corrigendum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.

[6]  V. Perry,et al.  Systemic inflammation and disease progression in Alzheimer disease , 2009, Neurology.

[7]  M. Etminan,et al.  NSAID Use and the Risk of Parkinson’s Disease , 2009, Drugs & aging.

[8]  M. Lynch,et al.  Fractalkine‐induced activation of the phosphatidylinositol‐3 kinase pathway attentuates microglial activation in vivo and in vitro , 2009, Journal of neurochemistry.

[9]  P. Bosco,et al.  Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease , 2009, Nature Genetics.

[10]  T. Kokjohn,et al.  Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions , 2009, Alzheimer's & Dementia.

[11]  E. Marcantonio,et al.  Delirium accelerates cognitive decline in Alzheimer disease , 2009, Neurology.

[12]  K. Williams,et al.  Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. , 2009, The American journal of pathology.

[13]  S. Inouye,et al.  Delirium in elderly adults: diagnosis, prevention and treatment , 2009, Nature Reviews Neurology.

[14]  J. Nabekura,et al.  Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals , 2009, The Journal of Neuroscience.

[15]  E. Hirsch,et al.  Neuroinflammation in Parkinson's disease: a target for neuroprotection? , 2009, The Lancet Neurology.

[16]  V. Perry,et al.  Microglial physiology: unique stimuli, specialized responses. , 2009, Annual review of immunology.

[17]  V. Perry,et al.  Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease , 2009, Biological Psychiatry.

[18]  T. Suuronen,et al.  Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors , 2009, Progress in Neurobiology.

[19]  L. Lue,et al.  Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation , 2009, Experimental Neurology.

[20]  Nick C Fox,et al.  Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study , 2008, Neurobiology of Disease.

[21]  R O Weller,et al.  Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain. , 2008, Brain : a journal of neurology.

[22]  J. Edwards,et al.  Exploring the full spectrum of macrophage activation , 2008, Nature Reviews Immunology.

[23]  T. Dawson,et al.  Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease , 2008, Current neurology and neuroscience reports.

[24]  Seth Love,et al.  Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial , 2008, The Lancet.

[25]  F. Heppner,et al.  Cerebral and Peripheral Amyloid Phagocytes— an Old Liaison with a New Twist , 2008, Neuron.

[26]  J. Hamilton.  Colony-stimulating factors in inflammation and autoimmunity , 2008, Nature Reviews Immunology.

[27]  K. Biber,et al.  Region‐specific expression of immunoregulatory proteins on microglia in the healthy CNS , 2008, Glia.

[28]  C. Ferrari,et al.  Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease , 2008, Brain : a journal of neurology.

[29]  J. Relton,et al.  Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease. , 2008, Brain : a journal of neurology.

[30]  J. Luchsinger.  Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: an epidemiological perspective. , 2008, European journal of pharmacology.

[31]  Donald R. Miller,et al.  Protective effects of NSAIDs on the development of Alzheimer disease , 2008, Neurology.

[32]  V. Perry,et al.  Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration , 2008, Neurobiology of Disease.

[33]  K. Rock,et al.  How dying cells alert the immune system to danger , 2008, Nature Reviews Immunology.

[34]  R O Weller,et al.  Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology , 2008, Neuropathology and applied neurobiology.

[35]  M. Goedert,et al.  The value of incomplete mouse models of Alzheimer’s disease , 2008, European Journal of Nuclear Medicine and Molecular Imaging.

[36]  Christopher T. Kodl,et al.  Cognitive dysfunction and diabetes mellitus. , 2008, Endocrine reviews.

[37]  F. Rossi,et al.  Local self-renewal can sustain CNS microglia maintenance and function throughout adult life , 2007, Nature Neuroscience.

[38]  M. Pepys.  Science and serendipity. , 2007, Clinical medicine.

[39]  R. Ransohoff.  Microgliosis: the questions shape the answers , 2007, Nature Neuroscience.

[40]  A. Mildner,et al.  Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions , 2007, Nature Neuroscience.

[41]  H. Kettenmann,et al.  Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.

[42]  R. Medzhitov.  Recognition of microorganisms and activation of the immune response , 2007, Nature.

[43]  Mark Rogers,et al.  NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? , 2007, Trends in pharmacological sciences.

[44]  Michael Ruse,et al.  Mechanisms and Models , 2007 .

[45]  Laura Fratiglioni,et al.  The epidemiology of the dementias: an update , 2007, Current opinion in psychiatry.

[46]  Patrick L. McGeer,et al.  NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies , 2007, Neurobiology of Aging.

[47]  Hans Lassmann,et al.  The Immunopathology of Multiple Sclerosis: An Overview , 2007, Brain pathology.

[48]  Qing Wang,et al.  The inflammatory response in stroke , 2007, Journal of Neuroimmunology.

[49]  Colm Cunningham,et al.  Systemic infections and inflammation affect chronic neurodegeneration , 2007, Nature Reviews Immunology.

[50]  M. Bianchi.  DAMPs, PAMPs and alarmins: all we need to know about danger , 2007, Journal of leukocyte biology.

[51]  W. Gan,et al.  The P2Y12 receptor regulates microglial activation by extracellular nucleotides , 2006, Nature Neuroscience.

[52]  W. Streit.  Microglial senescence: does the brain's immune system have an expiration date? , 2006, Trends in Neurosciences.

[53]  Hans Lassmann,et al.  Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. , 2006, Brain : a journal of neurology.

[54]  Michael Karin,et al.  Intracellular pattern recognition receptors in the host response , 2006, Nature.

[55]  G. Kollias,et al.  Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia , 2006, Science.

[56]  J. Julien,et al.  Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease , 2006, Neuron.

[57]  R. Hintzen,et al.  Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis. , 2006, Brain : a journal of neurology.

[58]  T. K. van den Berg,et al.  Signal Regulatory Proteins in the Immune System , 2005, The Journal of Immunology.

[59]  S. Gordon,et al.  Monocyte and macrophage heterogeneity , 2005, Nature Reviews Immunology.

[60]  V. Perry,et al.  Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration , 2005, The Journal of Neuroscience.

[61]  D. Wilcock,et al.  Dynamic Complexity of the Microglial Activation Response in Transgenic Models of Amyloid Deposition: Implications for Alzheimer Therapeutics , 2005, Journal of neuropathology and experimental neurology.

[62]  J. Suttles,et al.  Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences1 , 2005, The Journal of Immunology.

[63]  W. Gan,et al.  ATP mediates rapid microglial response to local brain injury in vivo , 2005, Nature Neuroscience.

[64]  F. Helmchen,et al.  Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo , 2005, Science.

[65]  N. Shahani,et al.  Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. , 2005, Biochimica et biophysica acta.

[66]  L. Moran,et al.  The facial nerve axotomy model , 2004, Brain Research Reviews.

[67]  J. Julien,et al.  Exacerbation of Motor Neuron Disease by Chronic Stimulation of Innate Immunity in a Mouse Model of Amyotrophic Lateral Sclerosis , 2004, The Journal of Neuroscience.

[68]  S. Scheff,et al.  Synaptic pathology in Alzheimer’s disease: a review of ultrastructural studies , 2003, Neurobiology of Aging.

[69]  N. Rothwell,et al.  Inflammation in central nervous system injury. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[70]  Minh N. H. Nguyen,et al.  Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice , 2003, Science.

[71]  M. Etminan,et al.  Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies , 2003, BMJ : British Medical Journal.

[72]  B. Dubois,et al.  Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization , 2003, Neurology.

[73]  Robert M Friedlander,et al.  Apoptosis and caspases in neurodegenerative diseases. , 2003, The New England journal of medicine.

[74]  C. Holmes,et al.  Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report , 2003, Nature Medicine.

[75]  M. V. van Breemen,et al.  Amyloid β plaque-associated proteins C1q and SAP enhance the Aβ1–42 peptide-induced cytokine secretion by adult human microglia in vitro , 2003, Acta Neuropathologica.

[76]  John Savill,et al.  A blast from the past: clearance of apoptotic cells regulates immune responses , 2002, Nature Reviews Immunology.

[77]  R. Banati,et al.  Visualising microglial activation in vivo , 2002, Glia.

[78]  S. Inouye,et al.  Delirium Superimposed on Dementia: A Systematic Review , 2002, Journal of the American Geriatrics Society.

[79]  A. Barclay,et al.  CD200 and membrane protein interactions in the control of myeloid cells. , 2002, Trends in immunology.

[80]  K. Horsburgh,et al.  Alterations in ApoE and ApoJ in Relation to Degeneration and Regeneration in a Mouse Model of Entorhinal Cortex Lesion , 2001, Experimental Neurology.

[81]  B. Blom,et al.  Down-regulation of the macrophage lineage through interaction with OX2 (CD200). , 2000, Science.

[82]  T. Ikizler,et al.  Transforming growth factor-β is involved in the pathogenesis of dialysis-related amyloidosis , 2000 .

[83]  J. Cano,et al.  The Single Intranigral Injection of LPS as a New Model for Studying the Selective Effects of Inflammatory Reactions on Dopaminergic System , 2000, Neurobiology of Disease.

[84]  C. Plata-salamán,et al.  Inflammation and Alzheimer’s disease , 2000, Neurobiology of Aging.

[85]  R. Stewart,et al.  Vascular Risk Factors and Alzheimer's Disease , 1999, The Australian and New Zealand journal of psychiatry.

[86]  R. Motter,et al.  Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse , 1999, Nature.

[87]  R B Banati,et al.  PK (‘peripheral benzodiazepine’) – binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK 11195 binding to activated microglia , 1997, Journal of neurocytology.

[88]  G. Kreutzberg.  Microglia: a sensor for pathological events in the CNS , 1996, Trends in Neurosciences.

[89]  L. Lovat,et al.  Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[90]  V. Perry,et al.  Turnover of resident microglia in the normal adult mouse brain , 1992, Neuroscience.

[91]  J. Miklossy,et al.  The Long-Distance Effects of Brain Lesions: Visualization of Myelinated Pathways in the Human Brain Using Polarizing and Fluorescence Microscopy , 1991, Journal of neuropathology and experimental neurology.

[92]  V. Perry,et al.  Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain , 1990, Neuroscience.

[93]  D. Troost,et al.  Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis , 1990, Neuropathology and applied neurobiology.

[94]  R. Kalaria,et al.  Serum amyloid P immunoreactivity in hippocampal tangles, plaques and vessels: implications for leakage across the blood-brain barrier in Alzheimer's disease , 1990, Brain Research.

[95]  W. Griffin,et al.  Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[96]  W. Hickey,et al.  Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. , 1988, Science.

[97]  Nick C Fox,et al.  Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease , 2009 .

[98]  Alberto Mantovani,et al.  Macrophage activation and polarization. , 2008, Frontiers in bioscience : a journal and virtual library.

[99]  M. D. de Leon,et al.  Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesis. , 2008, Journal of Alzheimer's disease : JAD.

[100]  R. Dantzer,et al.  From inflammation to sickness and depression: when the immune system subjugates the brain , 2008, Nature Reviews Neuroscience.

[101]  K. Lambertsen,et al.  Journal of Neuroinflammation Interleukin-1beta and Tumor Necrosis Factor-alpha Are Expressed by Different Subsets of Microglia and Macrophages after Ischemic Stroke in Mice , 2008 .

[102]  Manuel Buttini,et al.  Mice as models: transgenic approaches and Alzheimer's disease. , 2006, Journal of Alzheimer's disease : JAD.

[103]  Rajakrishnan Rajkumar,et al.  Grammar Engineering for CCG using Ant and XSLT ∗ , 2001 .

[104]  D. C. Henckel,et al.  Case report. , 1995, Journal.