Regulation of the mevalonate pathway
暂无分享,去创建一个
[1] M. Gelb,et al. Human lamin B contains a farnesylated cysteine residue. , 1989, The Journal of biological chemistry.
[2] P. Casey,et al. p21ras is modified by a farnesyl isoprenoid. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[3] F. Rottman,et al. Molecular cloning and sequence analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase from the human parasite Schistosoma mansoni. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[4] C. Slaughter,et al. cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper. , 1989, The Journal of biological chemistry.
[5] M. Brown,et al. Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells. , 1989, The Journal of biological chemistry.
[6] K. Svenson,et al. Identification of a zinc finger protein that binds to the sterol regulatory element. , 1989, Science.
[7] A. Varshavsky,et al. The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein , 1989, Nature.
[8] W. Schafer,et al. Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. , 1989, Science.
[9] M. Sinensky,et al. Sterol-independent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by mevalonate in Chinese hamster ovary cells. Magnitude and specificity. , 1989, The Journal of biological chemistry.
[10] C. Marshall,et al. All ras proteins are polyisoprenylated but only some are palmitoylated , 1989, Cell.
[11] W. Maltese,et al. Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability. , 1989, The Journal of biological chemistry.
[12] P. Dawson,et al. Purification of oxysterol binding protein from hamster liver cytosol. , 1989, The Journal of biological chemistry.
[13] L. Liscum,et al. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts , 1989, The Journal of cell biology.
[14] J. Hancock,et al. Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis. , 1989, The EMBO journal.
[15] G. Fink,et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[16] T. Osborne,et al. Purification of a protein doublet that binds to six TGG-containing sequences in the promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase. , 1988, The Journal of biological chemistry.
[17] W. Lennarz,et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase of the sea urchin embryo. Deduced structure and regulatory properties. , 1988, The Journal of biological chemistry.
[18] J. R. Smith,et al. Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A synthase. , 1988, The Journal of biological chemistry.
[19] J. R. Smith,et al. Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[20] L. Beck,et al. Incorporation of a product of mevalonic acid metabolism into proteins of Chinese hamster ovary cell nuclei , 1988, The Journal of cell biology.
[21] M. Basson,et al. Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis , 1988, Molecular and cellular biology.
[22] Nicolas Mermod,et al. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs , 1988, Nature.
[23] R. Deschenes,et al. Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[24] D. Chin,et al. Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase , 1988, Molecular and cellular biology.
[25] M. Nakanishi,et al. Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme. , 1988, The Journal of biological chemistry.
[26] N. Walworth,et al. A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast , 1988, Cell.
[27] H. Narita,et al. The membrane domain of 3-hydroxy-3-methylglutaryl-coenzyme A reductase confers endoplasmic reticulum localization and sterol-regulated degradation onto beta-galactosidase. , 1988, The Journal of biological chemistry.
[28] J. Glomset,et al. Evidence for modification of lamin B by a product of mevalonic acid. , 1988, The Journal of biological chemistry.
[29] D. Botstein,et al. The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery , 1988, Cell.
[30] T. Osborne,et al. Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element. , 1988, The Journal of biological chemistry.
[31] T. Südhof,et al. Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. , 1988, The Journal of biological chemistry.
[32] J. Sedat,et al. Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene [published erratum appears in J Cell Biol 1988 Jun;106(6):2225] , 1988, Journal of Cell Biology.
[33] M. Sinensky,et al. Somatic cell genetics and the study of cholesterol metabolism. , 1988, Biochimica et biophysica acta.
[34] J. Rothman,et al. Involvement of GTP-binding “G” proteins in transport through the Golgi stack , 1987, Cell.
[35] J. Aprille,et al. Activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase does not respond to ubiquinone uptake in cultured cells. , 1987, Biochemical Journal.
[36] K. Svenson,et al. Molecular Cloning and Sequence of a Cholesterol-Repressible Enzyme Related to Prenyltransferase in the Isoprene Biosynthetic Pathway , 1987, Molecular and cellular biology.
[37] T. Südhof,et al. Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. , 1987, The Journal of biological chemistry.
[38] R. Brady,et al. Group C Niemann‐Pick disease: faulty regulation of low‐density lipoprotein uptake and cholesterol storage in cultured fibroblasts , 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[39] M. Brown,et al. Partial deletion of membrane-bound domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase eliminates sterol-enhanced degradation and prevents formation of crystalloid endoplasmic reticulum , 1987, The Journal of cell biology.
[40] M. Caron,et al. A family of receptors coupled to guanine nucleotide regulatory proteins. , 1987, Biochemistry.
[41] J. R. Smith,et al. Optional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamsters. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[42] T. Südhof,et al. 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter , 1987, Cell.
[43] T. Südhof,et al. Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[44] R. G. Anderson,et al. Biogenesis of the crystalloid endoplasmic reticulum in UT-1 cells: evidence that newly formed endoplasmic reticulum emerges from the nuclear envelope , 1986, Journal of Cell Biology.
[45] M. Brown,et al. A receptor-mediated pathway for cholesterol homeostasis. , 1986, Science.
[46] M. Brown,et al. Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. II. Isolation of the gene and characterization of the 5' flanking region. , 1986, The Journal of biological chemistry.
[47] D. Skalnik,et al. The nucleotide sequence of Syrian hamster HMG-CoA reductase cDNA. , 1985, DNA.
[48] M. Brown,et al. Multiple mRNAs for 3-hydroxy-3-methylglutaryl coenzyme A reductase determined by multiple transcription initiation sites and intron splicing sites in the 5'-untranslated region. , 1985, The Journal of biological chemistry.
[49] B. Stevens,et al. Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation. , 1985, The Journal of biological chemistry.
[50] T. Osborne,et al. 5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription , 1985, Cell.
[51] T. Südhof,et al. The LDL receptor gene: a mosaic of exons shared with different proteins. , 1985, Science.
[52] J. Goldstein,et al. Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme , 1985, Cell.
[53] R. Stroud,et al. Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum. , 1985, The Journal of biological chemistry.
[54] M. Brown,et al. Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol. , 1984, Journal of lipid research.
[55] F. Taylor,et al. Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase. , 1984, Journal of Biological Chemistry.
[56] R. Schmidt,et al. Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. , 1984, The Journal of biological chemistry.
[57] T. Osborne,et al. HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions , 1984, Cell.
[58] D. Russell,et al. Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum , 1984, Nature.
[59] D. Goodman,et al. Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. , 1984, The Journal of biological chemistry.
[60] M. Brown,et al. Mutant clone of Chinese hamster ovary cells lacking 3-hydroxy-3 -methylglutaryl coenzyme A reductase. , 1983, The Journal of biological chemistry.
[61] L. Orci,et al. Ultrastructural analysis of crystalloid endoplasmic reticulum in UT-1 cells and its disappearance in response to cholesterol. , 1983, Journal of cell science.
[62] M. Brown,et al. Amplification of the gene for 3-hydroxy-3-methylglutaryl coenzyme A reductase, but not for the 53-kDa protein, in UT-1 cells. , 1983, The Journal of biological chemistry.
[63] C. Chang,et al. Revertants of a Chinese hamster ovary cell mutant resistant to suppression by an analogue of cholesterol: isolation and partial biochemical characterization. , 1982, Biochemistry.
[64] M. Brown,et al. Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[65] Y. Sakagami,et al. Peptidal Sex Hormones Inducing Conjugation Tube Formation in Compatible Mating-Type Cells of Tremella mesenterica. , 1981, Science.
[66] T. Chang,et al. Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells. , 1980, Journal of Biological Chemistry.
[67] M. Brown,et al. Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. , 1980, Journal of lipid research.
[68] R. Ross,et al. Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. , 1980, The Journal of biological chemistry.
[69] M. Wiley,et al. Essential role for mevalonate synthesis in DNA replication. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[70] M. Krieger,et al. Receptor-mediated uptake of low density lipoprotein reconstituted with 25-hydroxycholesteryl oleate suppresses 3-hydroxy-3-methylglutaryl-coenzyme A reductase and inhibits growth of human fibroblasts. , 1978, Proceedings of the National Academy of Sciences of the United States of America.
[71] Y. Kamiya,et al. Structure of rhodotorucine A, a novel lipopeptide, inducing mating tube formation in Rhodosporidium toruloides. , 1978, Biochemical and Biophysical Research Communications - BBRC.
[72] A. Kandutsch,et al. Biological activity of some oxygenated sterols. , 1978, Science.
[73] M. Brown,et al. Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. , 1978, The Journal of biological chemistry.
[74] A. Beaudet,et al. Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease. , 1975, The Journal of biological chemistry.
[75] M. Brown,et al. Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro. An adenine nucleotide-dependent reaction catalyzed by a factor in human fibroblasts. , 1975, The Journal of biological chemistry.
[76] A. Sim,et al. The AMP-activated protein kinase: a multisubstrate regulator of lipid metabolism , 1989 .
[77] Robert Tjian,et al. Promoter-specific activation of RNA polymerase II transcription by Sp1 , 1986 .
[78] W. Dynan. Promoters for housekeeping genes , 1986 .
[79] M. Brown,et al. The low-density lipoprotein pathway and its relation to atherosclerosis. , 1977, Annual review of biochemistry.
[80] J. Nordstrom,et al. Regulation of HMG-CoA reductase. , 1976, Advances in lipid research.
[81] R. H. Hall. N6-(δ2-Isopentenyl)adenosine: Chemical Reactions, Biosynthesis, Metabolism, and Significance to the Structure and Function of †RNA , 1970 .