Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.

[1]  S. Seneca,et al.  Pathogenic mutations in the 5' untranslated region of BCS1L mRNA in mitochondrial complex III deficiency. , 2009, Mitochondrion.

[2]  J. Russo,et al.  Regulation of energy metabolism pathways by estrogens and estrogenic chemicals and potential implications in obesity associated with increased exposure to endocrine disruptors. , 2009, Biochimica et biophysica acta.

[3]  Xiaofei Wang,et al.  Estrogen Receptor β as a Mitochondrial Vulnerability Factor* , 2009, Journal of Biological Chemistry.

[4]  R. Moreno-Sánchez,et al.  Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II , 2009, Clinical Cancer Research.

[5]  M. Pronicki,et al.  High prevalence of SURF1 c.845_846delCT mutation in Polish Leigh patients. , 2009, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[6]  R. Brinton,et al.  A select combination of clinically relevant phytoestrogens enhances estrogen receptor beta-binding selectivity and neuroprotective activities in vitro and in vivo. , 2009, Endocrinology.

[7]  A. Hegde,et al.  In vitro methylation of nuclear respiratory factor-2 binding sites suppresses the promoter activity of the human TOMM70 gene. , 2008, Gene.

[8]  YongSung Kim,et al.  PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. , 2008, Biochemical and biophysical research communications.

[9]  C. Klinge,et al.  Estrogenic control of mitochondrial function and biogenesis , 2008, Journal of cellular biochemistry.

[10]  Jie Xu,et al.  Increased vulnerability of brain to estrogen withdrawal-induced mitochondrial dysfunction with aging , 2008, Journal of bioenergetics and biomembranes.

[11]  M. Beal,et al.  Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis , 2008, Nature Clinical Practice Neurology.

[12]  A. Roy,et al.  Mitochondria-Dependent Reactive Oxygen Species-Mediated Programmed Cell Death Induced by 3,3′-Diindolylmethane through Inhibition of F0F1-ATP Synthase in Unicellular Protozoan Parasite Leishmania donovani , 2008, Molecular Pharmacology.

[13]  Stephen Safe,et al.  Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. , 2008, Journal of molecular endocrinology.

[14]  K. Hejzlarová,et al.  TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy , 2008, Nature Genetics.

[15]  Shivendra V. Singh,et al.  Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells* , 2008, Journal of Biological Chemistry.

[16]  P. Picotti,et al.  Functional and stoichiometric analysis of subunit e in bovine heart mitochondrial F0F1ATP synthase , 2008, Journal of bioenergetics and biomembranes.

[17]  S. Safe,et al.  Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: microarray and RNA interference studies. , 2008, Journal of molecular endocrinology.

[18]  V. Mootha,et al.  Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease. , 2008, American journal of human genetics.

[19]  J. Simpkins,et al.  Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection. , 2008, Endocrinology.

[20]  K. Hoffmeier,et al.  Two variants of the assembly factor Surf1 target specific terminal oxidases in Paracoccus denitrificans. , 2008, Biochimica et biophysica acta.

[21]  Roberta Diaz Brinton,et al.  Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease. , 2008, Advanced drug delivery reviews.

[22]  E. Marra,et al.  A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator. , 2008, Biochimica et biophysica acta.

[23]  J. Nilsen.  Estradiol and neurodegenerative oxidative stress , 2008, Frontiers in Neuroendocrinology.

[24]  L. Milanesi,et al.  17β-Estradiol signaling in skeletal muscle cells and its relationship to apoptosis , 2008, Steroids.

[25]  R. Brinton,et al.  The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications , 2008, Trends in Neurosciences.

[26]  Khadija Iqbal,et al.  Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. , 2008, Current medicinal chemistry.

[27]  G. McKhann,et al.  Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease , 2008, Nature Medicine.

[28]  H. G. Park,et al.  Estrogen-induced Bcl-2 expression after spinal cord injury is mediated through phosphoinositide-3-kinase/Akt-dependent CREB activation. , 2008, Journal of neurotrauma.

[29]  E. Levin.  Rapid signaling by steroid receptors. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[30]  B. Winblad,et al.  The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae , 2008, Proceedings of the National Academy of Sciences.

[31]  G. Skliris,et al.  Role of wild-type estrogen receptor-beta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells. , 2008, American journal of physiology. Endocrinology and metabolism.

[32]  M. Gottesman,et al.  SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial Metabolism , 2008, Molecular Cancer Research.

[33]  F. Fontanesi,et al.  Cytochrome c oxidase biogenesis: New levels of regulation , 2008, IUBMB life.

[34]  M. Mena,et al.  Gender differences and estrogen effects in parkin null mice , 2008, Journal of neurochemistry.

[35]  Y. Akao,et al.  A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells. , 2008, Biochemical and biophysical research communications.

[36]  D. Brann,et al.  Role of Dickkopf-1, an Antagonist of the Wnt/β-Catenin Signaling Pathway, in Estrogen-Induced Neuroprotection and Attenuation of Tau Phosphorylation , 2008, The Journal of Neuroscience.

[37]  M. Fändrich,et al.  Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice , 2008, Journal of Molecular Medicine.

[38]  Min Young Kim,et al.  Identification of cytochrome c oxidase subunit 6A1 as a suppressor of Bax-induced cell death by yeast-based functional screening. , 2008, Biochemical and biophysical research communications.

[39]  T. Ueda,et al.  The human mitochondrial translation release factor HMRF1L is methylated in the GGQ motif by the methyltransferase HMPrmC. , 2008, Biochemical and biophysical research communications.

[40]  J. Simpkins,et al.  Estrogen actions on mitochondria—Physiological and pathological implications , 2008, Molecular and Cellular Endocrinology.

[41]  Jie Shen,et al.  Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress , 2008, Proceedings of the National Academy of Sciences.

[42]  C. Gustafsson,et al.  Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro , 2008, Proceedings of the National Academy of Sciences.

[43]  T. Simoncini,et al.  Extra‐nuclear signaling of estrogen receptors , 2008, IUBMB life.

[44]  L. Wojnar,et al.  Detection of mitochondrial dysfunction by EPR technique in mouse model of dilated cardiomyopathy. , 2008, Free radical biology & medicine.

[45]  L. Putignani,et al.  Alteration of expression levels of the oxidative phosphorylation system (OXPHOS) in breast cancer cell mitochondria , 2008, Breast Cancer Research and Treatment.

[46]  F. Domann,et al.  α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II , 2008, Oncogene.

[47]  W. Baird,et al.  Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract. , 2008, Toxicology.

[48]  B. McEwen,et al.  Nuclear and extranuclear estrogen binding sites in the rat forebrain and autonomic medullary areas. , 2008, Endocrinology.

[49]  A. Halestrap,et al.  Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore. , 2008, Biochimica et biophysica acta.

[50]  L. Milanesi,et al.  Expression and localization of estrogen receptor α in the C2C12 murine skeletal muscle cell line , 2008, Journal of cellular biochemistry.

[51]  E. Condom,et al.  Altered expression of 12S/MT‐RNR1, MT‐CO2/COX2, and MT‐ATP6 mitochondrial genes in prostate cancer , 2008, The Prostate.

[52]  C. Beyer,et al.  Oestrogen Influences on Mitochondrial Gene Expression and Respiratory Chain Activity in Cortical and Mesencephalic Astrocytes , 2008, Journal of neuroendocrinology.

[53]  E. Cadenas,et al.  Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. , 2008, Endocrinology.

[54]  V. Procaccio,et al.  Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor α in Brain Endothelial Cells , 2008, Journal of Pharmacology and Experimental Therapeutics.

[55]  D. Winge,et al.  Mapping the Functional Interaction of Sco1 and Cox2 in Cytochrome Oxidase Biogenesis* , 2008, Journal of Biological Chemistry.

[56]  P. Cammarata,et al.  Mitochondrial superoxide dismutase activation with 17 β-estradiol-treated human lens epithelial cells , 2008, Molecular vision.

[57]  Ivano Bertini,et al.  Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer , 2008, Proceedings of the National Academy of Sciences.

[58]  T. Gulick,et al.  Nuclear Respiratory Factor 1 Controls Myocyte Enhancer Factor 2A Transcription to Provide a Mechanism for Coordinate Expression of Respiratory Chain Subunits* , 2008, Journal of Biological Chemistry.

[59]  R. Scarpulla,et al.  PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression* , 2008, Journal of Biological Chemistry.

[60]  T. Ueda,et al.  HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG , 2008, Genes to cells : devoted to molecular & cellular mechanisms.

[61]  C. Piantadosi,et al.  Transcriptional Regulation of SDHa Flavoprotein by Nuclear Respiratory Factor-1 Prevents Pseudo-hypoxia in Aerobic Cardiac Cells* , 2008, Journal of Biological Chemistry.

[62]  T. Gulick,et al.  Myocyte Enhancer Factor 2A Is Transcriptionally Autoregulated* , 2008, Journal of Biological Chemistry.

[63]  N. Avadhani,et al.  Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain* , 2008, Journal of Biological Chemistry.

[64]  P. Calabresi,et al.  NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: Implications for Huntington's disease , 2008, Neuroscience Letters.

[65]  R. Scarpulla.  Transcriptional paradigms in mammalian mitochondrial biogenesis and function. , 2008, Physiological reviews.

[66]  W. Park,et al.  2,4-dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells. , 2008, Toxicology in vitro : an international journal published in association with BIBRA.

[67]  E. Murphy,et al.  Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. , 2008, Physiological reviews.

[68]  A. Ferlini,et al.  Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies , 2008, Proceedings of the National Academy of Sciences.

[69]  A. Psarra,et al.  Steroid and thyroid hormone receptors in mitochondria , 2008, IUBMB life.

[70]  E. Levin,et al.  Estrogen receptors outside the nucleus in breast cancer , 2008, Breast Cancer Research and Treatment.

[71]  H. Sweeney,et al.  Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy , 2008, Nature Medicine.

[72]  J. Simpkins,et al.  Mitochondrial mechanisms of estrogen neuroprotection , 2008, Brain Research Reviews.

[73]  Xin-an Liu,et al.  Estradiol Attenuates Tau Hyperphosphorylation Induced by Upregulation of Protein Kinase-A , 2008, Neurochemical Research.

[74]  S. Guadagnini,et al.  Mitochondrial Dysfunction in Lyssavirus-Induced Apoptosis , 2008, Journal of Virology.

[75]  C. Klinge,et al.  Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. , 2008, Molecular endocrinology.

[76]  D. Lannigan,et al.  RNA Suppression of ERK2 Leads to Collapse of Mitochondrial Membrane Potential with Acute Oxidative Stress in Human Lens Epithelial Cells , 2008, American journal of physiology. Endocrinology and metabolism.

[77]  J. McNulty,et al.  Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria , 2008, Cancer biology & therapy.

[78]  Jie Xu,et al.  Possible role of mitochondrial dysfunction in central neurodegeneration of ovariectomized rats , 2008, Cell biochemistry and function.

[79]  J. Götz,et al.  Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice , 2008, Neurodegenerative Diseases.

[80]  M. Ikekita,et al.  Induction of mitochondria‐involved apoptosis in estrogen receptor‐negative cells by a novel tamoxifen derivative, ridaifen‐B , 2008, Cancer science.

[81]  Jie Xu,et al.  Effects of Phytoestrogen on Mitochondrial Structure and Function of Hippocampal CA1 Region of Ovariectomized Rats , 2008, Cellular and Molecular Neurobiology.

[82]  R. Jensen,et al.  Tom20 and Tom22 Share the Common Signal Recognition Pathway in Mitochondrial Protein Import* , 2008, Journal of Biological Chemistry.

[83]  M. Wong-Riley,et al.  Nuclear Respiratory Factor 1 Regulates All Ten Nuclear-encoded Subunits of Cytochrome c Oxidase in Neurons* , 2008, Journal of Biological Chemistry.

[84]  F. Fontanesi,et al.  Bot1p Is Required for Mitochondrial Translation, Respiratory Function, and Normal Cell Morphology in the Fission Yeast Schizosaccharomyces pombe , 2008, Eukaryotic Cell.

[85]  Y. Furuta,et al.  Increased mitochondrial DNA induces acquired docetaxel resistance in head and neck cancer cells , 2008, Oncogene.

[86]  A. Hegde,et al.  NRF-1 is the major transcription factor regulating the expression of the human TOMM34 gene. , 2008, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[87]  Ann Saada,et al.  C6ORF66 is an assembly factor of mitochondrial complex I. , 2008, American journal of human genetics.

[88]  J. Marín-García,et al.  Mitochondrial centrality in heart failure , 2008, Heart Failure Reviews.

[89]  R. Irwin,et al.  Estradiol In Vivo Regulation of Brain Mitochondrial Proteome , 2007, The Journal of Neuroscience.

[90]  A. Starkov,et al.  The mitochondrial respiratory chain is a modulator of apoptosis , 2007, The Journal of cell biology.

[91]  Xiu-fang Wang,et al.  Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress. , 2007, Cancer research.

[92]  Yongqiang Chen,et al.  Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species , 2007, Journal of Cell Science.

[93]  J. Russo,et al.  ERbeta shifts from mitochondria to nucleus during estrogen-induced neoplastic transformation of human breast epithelial cells and is involved in estrogen-induced synthesis of mitochondrial respiratory chain proteins. , 2007, Biochimica et biophysica acta.

[94]  N. Chandel,et al.  Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis , 2007, Molecular and Cellular Biology.

[95]  V. Procaccio,et al.  Estrogen suppresses brain mitochondrial oxidative stress in female and male rats , 2007, Brain Research.

[96]  B. Warscheid,et al.  Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly , 2007, The EMBO journal.

[97]  P. Carbon,et al.  Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene. , 2007, Gene.

[98]  Xiu-fang Wang,et al.  Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria. , 2007, Molecular aspects of medicine.

[99]  P. Jansen-Dürr,et al.  Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells. , 2007, Free radical biology & medicine.

[100]  R. Karry,et al.  Sp1 Expression Is Disrupted in Schizophrenia; A Possible Mechanism for the Abnormal Expression of Mitochondrial Complex I Genes, NDUFV1 and NDUFV2 , 2007, PloS one.

[101]  T. Hewett,et al.  Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. , 2007, The Journal of clinical investigation.

[102]  N. Pfanner,et al.  Diverse mechanisms and machineries for import of mitochondrial proteins , 2007, Biological chemistry.

[103]  E. Shoubridge,et al.  The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. , 2007, Molecular biology of the cell.

[104]  R. Brinton,et al.  Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons. , 2007, Journal of medicinal chemistry.

[105]  K. Ono,et al.  Estrogen has anti-amyloidogenic effects on Alzheimer's beta-amyloid fibrils in vitro. , 2007, Biochemical and biophysical research communications.

[106]  R. Ferrante,et al.  Nortriptyline delays disease onset in models of chronic neurodegeneration , 2007, The European journal of neuroscience.

[107]  H. Choi,et al.  Identification of mitochondrial FoF1‐ATP synthase involved in liver metastasis of colorectal cancer , 2007, Cancer science.

[108]  J. Silke,et al.  Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease , 2007, The EMBO journal.

[109]  E. Ekblad,et al.  Demonstration of mitochondrial oestrogen receptor beta and oestrogen-induced attenuation of cytochrome c oxidase subunit I expression in human periodontal ligament cells. , 2007, Archives of oral biology.

[110]  A. Psarra,et al.  Differential distribution of glucocorticoid and estrogen receptor isoforms: localization of GRbeta and ERalpha in nucleoli and GRalpha and ERbeta in the mitochondria of human osteosarcoma SaOS-2 and hepatocarcinoma HepG2 cell lines. , 2007, Journal of musculoskeletal & neuronal interactions.

[111]  P. Härkönen,et al.  Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen. , 2007, Endocrinology.

[112]  J. Kuret,et al.  Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy* , 2007, Journal of Biological Chemistry.

[113]  M. Guo,et al.  Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease , 2007, Current Opinion in Neurobiology.

[114]  J. Bienkowska,et al.  Estrogen Receptors α and β Mediate Distinct Pathways of Vascular Gene Expression, Including Genes Involved in Mitochondrial Electron Transport and Generation of Reactive Oxygen Species , 2007 .

[115]  Massimo Zeviani,et al.  Impaired complex III assembly associated with BCS1L gene mutations in isolated mitochondrial encephalopathy. , 2007, Human molecular genetics.

[116]  S. Leal,et al.  Mitochondrial genetic background modifies breast cancer risk. , 2007, Cancer research.

[117]  Y. Furuichi,et al.  Neuroprotective efficacy of FR901459, a novel derivative of cyclosporin A, in in vitro mitochondrial damage and in vivo transient cerebral ischemia models , 2007, Brain Research.

[118]  R. Hayashi,et al.  Nuclear respiratory factor 2 activates transcription of human mitochondrial translation initiation factor 2 gene. , 2007, Mitochondrion.

[119]  D. Bourdette,et al.  Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis , 2007, Proceedings of the National Academy of Sciences.

[120]  R Mark Payne,et al.  Mitochondrial protein import and human health and disease. , 2007, Biochimica et biophysica acta.

[121]  M. Lazarou,et al.  Analysis of the Assembly Profiles for Mitochondrial- and Nuclear-DNA-Encoded Subunits into Complex I , 2007, Molecular and Cellular Biology.

[122]  Takashi Suzuki,et al.  Aromatase localization in human breast cancer tissues: possible interactions between intratumoral stromal and parenchymal cells. , 2007, Cancer research.

[123]  Amy S. Lee,et al.  GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. , 2007, Cancer research.

[124]  J. Blesa,et al.  NRF-2 transcription factor is required for human TOMM20 gene expression. , 2007, Gene.

[125]  W. Craigen,et al.  Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death , 2007, Nature Cell Biology.

[126]  James D. Yager,et al.  Mitochondrial estrogen receptors – new insights into specific functions , 2007, Trends in Endocrinology & Metabolism.

[127]  I. Chaudry,et al.  17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage. , 2007, Molecular immunology.

[128]  T. Yamakawa,et al.  Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases , 2007, Acta Pharmacologica Sinica.

[129]  C. Gustafsson,et al.  Mitochondrial transcription and its regulation in mammalian cells. , 2007, Trends in biochemical sciences.

[130]  Yong Li,et al.  RNase MRP RNA and human genetic diseases , 2007, Cell Research.

[131]  J. Seidman,et al.  Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome. , 2007, The New England journal of medicine.

[132]  J. Yates,et al.  Adaptation of energy metabolism in breast cancer brain metastases. , 2007, Cancer research.

[133]  Xiu-fang Wang,et al.  Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II , 2007, Journal of bioenergetics and biomembranes.

[134]  N. Hamasaki,et al.  Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions. , 2007, Mitochondrion.

[135]  P. Ghafourifar,et al.  Tamoxifen induces oxidative stress and mitochondrial apoptosis via stimulating mitochondrial nitric oxide synthase. , 2007, Cancer research.

[136]  S. Shankar,et al.  Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa. , 2007, Carcinogenesis.

[137]  A. Eckert,et al.  Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function—role of glucose metabolism and insulin signalling , 2007, Archives of physiology and biochemistry.

[138]  F. Fontanesi,et al.  Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular process. , 2006, American journal of physiology. Cell physiology.

[139]  R. Santen,et al.  Role of receptor complexes in the extranuclear actions of estrogen receptor alpha in breast cancer. , 2006, Endocrine-related cancer.

[140]  Bastiaan R Bloem,et al.  Gender differences in Parkinson’s disease , 2006, Journal of Neurology, Neurosurgery & Psychiatry.

[141]  R. A. Butow,et al.  Mitochondrial retrograde signaling. , 2006, Annual review of genetics.

[142]  R. Irwin,et al.  Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function , 2006, BMC Neuroscience.

[143]  Shivendra V. Singh,et al.  Benzyl isothiocyanate–induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak , 2006, Molecular Cancer Therapeutics.

[144]  J. Blesa,et al.  Distinct functional contributions of 2 GABP-NRF-2 recognition sites within the context of the human TOMM70 promoter. , 2006, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[145]  J. Hayashi,et al.  Respiratory chain deficiency slows down cell‐cycle progression via reduced ROS generation and is associated with a reduction of p21CIP1/WAF1 , 2006, Journal of cellular physiology.

[146]  Keshav K. Singh,et al.  Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer cells , 2006 .

[147]  T. Mitsui,et al.  Parkin affects mitochondrial function and apoptosis in neuronal and myogenic cells. , 2006, Biochemical and biophysical research communications.

[148]  I. Chaudry,et al.  Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage. , 2006, Journal of molecular and cellular cardiology.

[149]  Marty C. Brandon,et al.  Mitochondrial mutations in cancer , 2006, Oncogene.

[150]  Keshav K. Singh,et al.  Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer. , 2006, Cancer biology & therapy.

[151]  C. Fenselau,et al.  Alterations in the mitochondrial proteome of adriamycin resistant MCF-7 breast cancer cells. , 2006, Journal of proteome research.

[152]  Brian Walters,et al.  Cardiotoxicity of the cancer therapeutic agent imatinib mesylate , 2006, Nature Medicine.

[153]  W. Zwerschke,et al.  Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts , 2006, Experimental Gerontology.

[154]  W. Müller,et al.  Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease , 2006, Experimental Gerontology.

[155]  R. Santen,et al.  Membrane initiated estrogen signaling in breast cancer. , 2006, Biology of reproduction.

[156]  Changan Jiang,et al.  Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin , 2006, Nature.

[157]  Oksana Gavrilova,et al.  p53 Regulates Mitochondrial Respiration , 2006, Science.

[158]  M. Wong-Riley,et al.  Nuclear respiratory factor 2 senses changing cellular energy demands and its silencing down-regulates cytochrome oxidase and other target gene mRNAs. , 2006, Gene.

[159]  Ivan H. Still,et al.  Proteomic analysis of proteins involved in mitochondria-to-nucleus retrograde response in human cancer cells , 2006 .

[160]  P. Bernardi,et al.  The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents? , 2006, Cell Death and Differentiation.

[161]  S. Dimauro,et al.  Early‐onset familial parkinsonism due to POLG mutations , 2006, Annals of neurology.

[162]  J. Simpkins,et al.  Novel Mechanisms for Estrogen-Induced Neuroprotection , 2006, Experimental biology and medicine.

[163]  D. Wallace,et al.  Functional estrogen receptors in the mitochondria of breast cancer cells. , 2006, Molecular biology of the cell.

[164]  S. Pepe,et al.  Energy deficiency in the failing heart: linking increased reactive oxygen species and disruption of oxidative phosphorylation rate. , 2006, Biochimica et biophysica acta.

[165]  I. Fabregat,et al.  Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase. , 2006, Carcinogenesis.

[166]  Fabio Di Lisa,et al.  The mitochondrial permeability transition from in vitro artifact to disease target , 2006, The FEBS journal.

[167]  Catarina R. Oliveira,et al.  Tamoxifen and Estradiol Interact with the Flavin Mononucleotide Site of Complex I Leading to Mitochondrial Failure* , 2006, Journal of Biological Chemistry.

[168]  L. Smeeth,et al.  Hormone replacement therapy and cataract: a population-based case–control study , 2006, Eye.

[169]  T. Mitsui,et al.  Parkin enhances mitochondrial biogenesis in proliferating cells. , 2006, Human molecular genetics.

[170]  E. Levin,et al.  Estrogen Prevents Cardiomyocyte Apoptosis through Inhibition of Reactive Oxygen Species and Differential Regulation of p38 Kinase Isoforms* , 2006, Journal of Biological Chemistry.

[171]  R. Scarpulla,et al.  Nuclear control of respiratory gene expression in mammalian cells , 2006, Journal of cellular biochemistry.

[172]  A. Psarra,et al.  The mitochondrion as a primary site of action of steroid and thyroid hormones: Presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells , 2006, Molecular and Cellular Endocrinology.

[173]  V. Procaccio,et al.  Estrogen and mitochondria: a new paradigm for vascular protection? , 2006, Molecular interventions.

[174]  I. Fichtner,et al.  Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance , 2006, Proteomics.

[175]  J. Yager,et al.  Estrogen carcinogenesis in breast cancer. , 2006, The New England journal of medicine.

[176]  E. Sato,et al.  Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death. , 2005, American journal of physiology. Cell physiology.

[177]  I. Chaudry,et al.  PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage. , 2005, American journal of physiology. Heart and circulatory physiology.

[178]  Utpal Banerjee,et al.  Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila. , 2005, Developmental cell.

[179]  E. Murphy,et al.  Bcl-2 regulation of mitochondrial energetics. , 2005, Trends in cardiovascular medicine.

[180]  J. Russo,et al.  Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications. , 2005, Biochimica et biophysica acta.

[181]  C. Eng,et al.  Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. , 2005, JAMA.

[182]  M. Wong-Riley,et al.  Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons? , 2005, Gene.

[183]  Kehinde A. Ayoola,et al.  Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation , 2005, The Journal of comparative neurology.

[184]  P. Härkönen,et al.  Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells , 2005, Apoptosis.

[185]  V. Procaccio,et al.  Estrogen Increases Mitochondrial Efficiency and Reduces Oxidative Stress in Cerebral Blood Vessels , 2005, Molecular Pharmacology.

[186]  Rutger O. Vogel,et al.  Human mitochondrial complex I assembly is mediated by NDUFAF1 , 2005, The FEBS journal.

[187]  M. Minczuk,et al.  Human ATP‐dependent RNA/DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP , 2005, The FEBS journal.

[188]  A. Psarra,et al.  Differential subcellular distribution of estrogen receptor isoforms: localization of ERalpha in the nucleoli and ERbeta in the mitochondria of human osteosarcoma SaOS-2 and hepatocarcinoma HepG2 cell lines. , 2005, Biochimica et biophysica acta.

[189]  S. Bulun,et al.  Regulation of Aromatase Expression in Estrogen-Responsive Breast and Uterine Disease: From Bench to Treatment , 2005, Pharmacological Reviews.

[190]  S. Korsmeyer,et al.  Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[191]  K. Sunagawa,et al.  Overexpression of Mitochondrial Transcription Factor A Ameliorates Mitochondrial Deficiencies and Cardiac Failure After Myocardial Infarction , 2005, Circulation.

[192]  L. Murphy,et al.  Differential expression and comparative subcellular localization of estrogen receptor beta isoforms in virally transformed and normal cultured human lens epithelial cells. , 2005, Experimental eye research.

[193]  E. Levin,et al.  Integration of the extranuclear and nuclear actions of estrogen. , 2005, Molecular endocrinology.

[194]  M. Montero,et al.  Modulation of mitochondrial Ca2+ uptake by estrogen receptor agonists and antagonists , 2005 .

[195]  Quentin Felty,et al.  Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling , 2005, Oncogene.

[196]  M. Minczuk,et al.  The 5' region of the human hSUV3 gene encoding mitochondrial DNA and RNA helicase: promoter characterization and alternative pre-mRNA splicing. , 2005, Biochimica et biophysica acta.

[197]  R. Ravid,et al.  Proteomic and Functional Analyses Reveal a Mitochondrial Dysfunction in P301L Tau Transgenic Mice* , 2005, Journal of Biological Chemistry.

[198]  R. Karas,et al.  Molecular and Cellular Basis of Cardiovascular Gender Differences , 2005, Science.

[199]  N. Howell,et al.  Development of 17α‐Estradiol as a Neuroprotective Therapeutic Agent: Rationale and Results from a Phase I Clinical Study , 2005, Annals of the New York Academy of Sciences.

[200]  W. Antholine,et al.  Assembly of Cytochrome-c Oxidase in the Absence of Assembly Protein Surf1p Leads to Loss of the Active Site Heme* , 2005, Journal of Biological Chemistry.

[201]  J. McNulty,et al.  Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis , 2005, Apoptosis.

[202]  F. Giblin,et al.  17beta-estradiol stimulates MAPK signaling pathway in human lens epithelial cell cultures preventing collapse of mitochondrial membrane potential during acute oxidative stress. , 2005, Mitochondrion.

[203]  D. Roy,et al.  Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers. , 2005, Biochemistry.

[204]  Tetsuya Watanabe,et al.  Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death , 2005, Nature.

[205]  Jeffrey Robbins,et al.  Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death , 2005, Nature.

[206]  Martín C Abba,et al.  Gene expression signature of estrogen receptor α status in breast cancer , 2005, BMC Genomics.

[207]  Shivendra V. Singh,et al.  Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent. , 2005, Cancer research.

[208]  P. Moreira,et al.  Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen , 2005, Neuropharmacology.

[209]  V. Gogvadze,et al.  Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis. , 2005, Cancer biology & therapy.

[210]  K. Korach,et al.  Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury. , 2005, Journal of molecular and cellular cardiology.

[211]  R. Scarpulla,et al.  Control of Mitochondrial Transcription Specificity Factors (TFB1M and TFB2M) by Nuclear Respiratory Factors (NRF-1 and NRF-2) and PGC-1 Family Coactivators , 2005, Molecular and Cellular Biology.

[212]  J. Simpkins,et al.  Mitochondria play a central role in estrogen-induced neuroprotection. , 2005, Current drug targets. CNS and neurological disorders.

[213]  D. Krause,et al.  Estrogen Receptor Activation of Phosphoinositide-3 Kinase, Akt, and Nitric Oxide Signaling in Cerebral Blood Vessels: Rapid and Long-Term Effects , 2005, Molecular Pharmacology.

[214]  J. Fish,et al.  Discovery of a Major D-Loop Replication Origin Reveals Two Modes of Human mtDNA Synthesis , 2004, Science.

[215]  J. Yager,et al.  Estrogen's Effects on Mitochondrial Gene Expression: Mechanisms and Potential Contributions to Estrogen Carcinogenesis , 2004, Annals of the New York Academy of Sciences.

[216]  Liqin Wang,et al.  Antiapoptotic effects of estrogen in normal and cancer human cervical epithelial cells. , 2004, Endocrinology.

[217]  Young-Jae Nam,et al.  The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis , 2004, Circulation research.

[218]  N. Hamasaki,et al.  Architectural Role of Mitochondrial Transcription Factor A in Maintenance of Human Mitochondrial DNA , 2004, Molecular and Cellular Biology.

[219]  J. Simpkins,et al.  Estrogen-Like Compounds for Ischemic Neuroprotection , 2004, Stroke.

[220]  M. Grabowski,et al.  Diagnostic value of BNP in suspected perimyocarditis--a preliminary report. , 2004, Kardiologia polska.

[221]  M. Kampa,et al.  Estrogen exerts neuroprotective effects via membrane estrogen receptors and rapid Akt/NOS activation , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[222]  J. Yager,et al.  Binding of MCF‐7 cell mitochondrial proteins and recombinant human estrogen receptors α and β to human mitochondrial dna estrogen response elements , 2004 .

[223]  Byong Chul Yoo,et al.  Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance. , 2004, Cancer research.

[224]  P. Rosenberg.  Mitochondrial dysfunction and heart disease. , 2004, Mitochondrion.

[225]  M. Bauer,et al.  Significance of Respirasomes for the Assembly/Stability of Human Respiratory Chain Complex I* , 2004, Journal of Biological Chemistry.

[226]  C. Eng,et al.  Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. , 2004, JAMA.

[227]  M. Beal.  Mitochondrial Dysfunction and Oxidative Damage in Alzheimer's and Parkinson's Diseases and Coenzyme Q10 as a Potential Treatment , 2004, Journal of bioenergetics and biomembranes.

[228]  J. Wimalasena,et al.  Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt. , 2004, Molecular biology of the cell.

[229]  I. Goldberg,et al.  γ Synuclein, a Novel Heat-Shock Protein-Associated Chaperone, Stimulates Ligand-Dependent Estrogen Receptor α Signaling and Mammary Tumorigenesis , 2004, Cancer Research.

[230]  P. Schofield,et al.  The prevalence of SDHB, SDHC, and SDHD mutations in patients with head and neck paraganglioma and association of mutations with clinical features , 2004, Journal of Medical Genetics.

[231]  E. Sauter,et al.  Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid. , 2004, Carcinogenesis.

[232]  Roberta Diaz Brinton,et al.  Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons , 2004, Brain Research.

[233]  P. Kaplan,et al.  Association of mutations in SCO2, a cytochrome c oxidase assembly gene, with early fetal lethality. , 2004, Archives of neurology.

[234]  J. Yager,et al.  Mitochondrial localization of ER and ER in human MCF7 cells , 2004 .

[235]  R. Nussbaum,et al.  Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 , 2004, Science.

[236]  N. Avadhani,et al.  Mitochondrial signaling: the retrograde response. , 2004, Molecular cell.

[237]  J. Blesa,et al.  NRF-2 transcription factor is essential in promoting human Tomm70 gene expression. , 2004, Mitochondrion.

[238]  J. Simpkins,et al.  Subcellular distribution of native estrogen receptor α and β subtypes in cultured human lens epithelial cells , 2004 .

[239]  C. Bruno,et al.  Respiratory complex III is required to maintain complex I in mammalian mitochondria. , 2004, Molecular cell.

[240]  Anne-Marie Brun-Zinkernagel,et al.  Mitochondrial localization of estrogen receptor β , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[241]  M. Mori,et al.  Mitochondrial Import Receptors Tom20 and Tom22 Have Chaperone-like Activity* , 2004, Journal of Biological Chemistry.

[242]  S. Seneca,et al.  Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12 , 2004, Journal of Medical Genetics.

[243]  Dean P. Jones,et al.  The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore , 2004, Nature.

[244]  Qi Chen,et al.  Genistein ameliorates beta-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis. , 2004, Free radical biology & medicine.

[245]  Li Zhang,et al.  A missense mutation (L166P) in DJ‐1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo‐oligomerization , 2003, Journal of neurochemistry.

[246]  P. Oliveira,et al.  Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin‐induced diabetic rats , 2003, FEBS letters.

[247]  J. Yager,et al.  Enhanced mitochondrial gene transcript, ATP, bcl-2 protein levels, and altered glutathione distribution in ethinyl estradiol-treated cultured female rat hepatocytes. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[248]  J. Custódio,et al.  Comparison of the changes in adenine nucleotides of rat liver mitochondria induced by tamoxifen and 4-hydroxytamoxifen. , 2003, Toxicology in vitro : an international journal published in association with BIBRA.

[249]  C. Brenner,et al.  The adenine nucleotide translocator: a new potential chemotherapeutic target. , 2003, Current drug targets.

[250]  W. Plunkett,et al.  Inhibition of Mitochondrial Respiration , 2003, Journal of Biological Chemistry.

[251]  M. Pasdar,et al.  Bcl-2 expression decreases cadherin-mediated cell-cell adhesion , 2003, Journal of Cell Science.

[252]  J. Wiley,et al.  The human mitochondrial translation initiation factor 2 gene (MTIF2): transcriptional analysis and identification of a pseudogene. , 2003, Biochimica et biophysica acta.

[253]  Serge Gauthier,et al.  Alzheimer's disease: the pharmacological pathway , 2003, Fundamental & clinical pharmacology.

[254]  I. Goldberg,et al.  Stimulation of Estrogen Receptor Signaling by γ Synuclein , 2003 .

[255]  H. Itoh,et al.  P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA. , 2003, Cancer research.

[256]  J. Lillehaug,et al.  Increased expression of genes encoding mitochondrial proteins in papillary thyroid carcinomas. , 2003, Thyroid : official journal of the American Thyroid Association.

[257]  D. Murphy,et al.  Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen , 2003, Endocrine.

[258]  J. Simpkins,et al.  Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability. , 2003, Investigative ophthalmology & visual science.

[259]  S. Korsmeyer,et al.  Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release. , 2003, Cancer research.

[260]  J. Paul Robinson,et al.  Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production* , 2003, The Journal of Biological Chemistry.

[261]  J. Lemasters,et al.  Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. , 2003, Gastroenterology.

[262]  M. Prevost,et al.  Bcl-2 and Bax modulate adenine nucleotide translocase activity. , 2003, Cancer research.

[263]  C. Sekeris,et al.  The Effects of Steroid Hormones on the Transcription of Genes Encoding Enzymes of Oxidative Phosphorylation , 2003, Experimental physiology.

[264]  D. Shapiro,et al.  Estrogen Receptor-dependent and Estrogen Receptor-independent Pathways for Tamoxifen and 4-Hydroxytamoxifen-induced Programmed Cell Death* , 2002, The Journal of Biological Chemistry.

[265]  Sushant Kachhap,et al.  Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells , 2002, Molecular Cancer.

[266]  K. Ghoshal,et al.  Mitochondrial Transcription Factor A and Its Downstream Targets Are Up-regulated in a Rat Hepatoma* , 2002, The Journal of Biological Chemistry.

[267]  George Perry,et al.  Role of mitochondrial dysfunction in Alzheimer's disease , 2002, Journal of neuroscience research.

[268]  J. Custódio,et al.  4-Hydroxytamoxifen induces slight uncoupling of mitochondrial oxidative phosphorylation system in relation to the deleterious effects of tamoxifen. , 2002, Toxicology.

[269]  J. Custódio,et al.  4-Hydroxytamoxifen is a potent inhibitor of the mitochondrial permeability transition. , 2002, Mitochondrion.

[270]  A. Halestrap,et al.  Sanglifehrin A Acts as a Potent Inhibitor of the Mitochondrial Permeability Transition and Reperfusion Injury of the Heart by Binding to Cyclophilin-D at a Different Site from Cyclosporin A* , 2002, The Journal of Biological Chemistry.

[271]  K. Korach,et al.  Estrogen Receptors: Structure, Mechanisms and Function , 2002, Reviews in Endocrine and Metabolic Disorders.

[272]  H. Uramoto,et al.  Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA. , 2002, Biochemical and biophysical research communications.

[273]  R. Karas,et al.  The protective effects of estrogen on the cardiovascular system. , 2002, The New England journal of medicine.

[274]  A. Jekabsone,et al.  Estrogens prevent calcium‐induced release of cytochrome c from heart mitochondria , 2002, FEBS letters.

[275]  C. Gustafsson,et al.  Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA , 2002, Nature Genetics.

[276]  R. Scarpulla,et al.  Nuclear activators and coactivators in mammalian mitochondrial biogenesis. , 2002, Biochimica et biophysica acta.

[277]  I. Leav,et al.  Gene Expression Profiling of Testosterone and Estradiol-17β-Induced Prostatic Dysplasia in Noble Rats and Response to the Antiestrogen ICI 182,780. , 2002, Endocrinology.

[278]  P. Chambon,et al.  Estrogen Receptor-&agr; Mediates the Protective Effects of Estrogen Against Vascular Injury , 2002, Circulation research.

[279]  A. Fukamizu,et al.  Characterization and identification of promoter elements in the mouse COX17 gene. , 2002, Biochimica et biophysica acta.

[280]  Ò. Miró,et al.  Electron Transport Chain Defects in Heart Failure , 2002, Heart Failure Reviews.

[281]  P. Lescuyer,et al.  YY1 and Sp1 activate transcription of the human NDUFS8 gene encoding the mitochondrial complex I TYKY subunit. , 2002, Biochimica et biophysica acta.

[282]  Y. Pak,et al.  Characterization of the 5'-flanking region of the rat gene for mitochondrial transcription factor A (Tfam). , 2002, Biochimica et biophysica acta.

[283]  H. Ohigashi,et al.  Involvement of the Mitochondrial Death Pathway in Chemopreventive Benzyl Isothiocyanate-induced Apoptosis* , 2002, The Journal of Biological Chemistry.

[284]  R. Scarpulla.  Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells. , 2002, Gene.

[285]  S. Shin,et al.  Formation and Removal of α-Synuclein Aggregates in Cells Exposed to Mitochondrial Inhibitors* , 2002, The Journal of Biological Chemistry.

[286]  G. Kroemer,et al.  The adenine nucleotide translocator in apoptosis. , 2002, Biochimie.

[287]  E. Shoubridge,et al.  Cytochrome c oxidase deficiency due to mutations in SCO2, encoding a mitochondrial copper-binding protein, is rescued by copper in human myoblasts. , 2001, Human molecular genetics.

[288]  B. Munoz,et al.  Hormone replacement therapy and lens opacities: the Salisbury Eye Evaluation project. , 2001, Archives of ophthalmology.

[289]  J. Custódio,et al.  Mechanisms of the deleterious effects of tamoxifen on mitochondrial respiration rate and phosphorylation efficiency. , 2001, Toxicology and applied pharmacology.

[290]  E. Shoubridge,et al.  Homozygosity (E140K) in SCO2 causes delayed infantile onset of cardiomyopathy and neuropathy , 2001, Neurology.

[291]  E Gabrielson,et al.  Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. , 2001, Cancer research.

[292]  K. Korach,et al.  The Multifaceted Mechanisms of Estradiol and Estrogen Receptor Signaling* , 2001, The Journal of Biological Chemistry.

[293]  H. Shaban,et al.  Cytochrome c oxidase inhibition by N-retinyl-N-retinylidene ethanolamine, a compound suspected to cause age-related macula degeneration. , 2001, Archives of biochemistry and biophysics.

[294]  R. Traystman,et al.  Estrogen and Bcl-2: Gene Induction and Effect of Transgene in Experimental Stroke , 2001, The Journal of Neuroscience.

[295]  R. Boland,et al.  Subcellular distribution of native estrogen receptor α and β isoforms in rabbit uterus and ovary , 2001 .

[296]  M. Holick,et al.  Differential cellular localization of estrogen receptor α in uterine and mammary cells , 2001, Molecular and Cellular Endocrinology.

[297]  N. Pfanner,et al.  Versatility of the mitochondrial protein import machinery , 2001, Nature Reviews Molecular Cell Biology.

[298]  P. Rustin,et al.  Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[299]  V. Seewaldt,et al.  Tamoxifen but Not 4-Hydroxytamoxifen Initiates Apoptosis in p53(−) Normal Human Mammary Epithelial Cells by Inducing Mitochondrial Depolarization* , 2001, The Journal of Biological Chemistry.

[300]  Andreas Wenzel,et al.  Age-related Macular Degeneration , 2000, The Journal of Biological Chemistry.

[301]  D. R. Gross,et al.  Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats. , 2000, American journal of physiology. Heart and circulatory physiology.

[302]  E. Levin,et al.  Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer. , 2000, Molecular endocrinology.

[303]  S. Shimohama,et al.  Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[304]  J. Yager,et al.  Inhibition of TGF-beta-induced apoptosis by ethinyl estradiol in cultured, precision cut rat liver slices and hepatocytes. , 2000, Carcinogenesis.

[305]  K. Hoyt,et al.  Inhibition of glutamate-induced mitochondrial depolarization by tamoxifen in cultured neurons. , 2000, The Journal of pharmacology and experimental therapeutics.

[306]  D. R. Gross,et al.  Myocardial ischemia-reperfusion injury in estrogen receptor-alpha knockout and wild-type mice. , 2000, American journal of physiology. Heart and circulatory physiology.

[307]  Y Li,et al.  [Mitochondria and apoptosis]. , 2000, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].

[308]  M. I. Lomax,et al.  Human COX6A1 gene: promoter analysis, cDNA isolation and expression in the monkey brain. , 2000, Gene.

[309]  C. Grimaldi,et al.  Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[310]  J. Yager,et al.  Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment. , 1999, Toxicological sciences : an official journal of the Society of Toxicology.

[311]  M. Taniwaki,et al.  Characterization of the human SDHD gene encoding the small subunit of cytochrome b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase. , 1999, Biochimica et biophysica acta.

[312]  M. Mendelsohn,et al.  Protective effects of estrogen on the cardiovascular system. , 1999, The American journal of cardiology.

[313]  C. K. Too,et al.  Estrogen stimulates expression of adenine nucleotide translocator ANT1 messenger RNA in female rat hearts , 1999, Molecular and Cellular Endocrinology.

[314]  M. Crompton,et al.  Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore. , 1998, European journal of biochemistry.

[315]  J. Yager,et al.  Enhanced levels of several mitochondrial mRNA transcripts and mitochondrial superoxide production during ethinyl estradiol-induced hepatocarcinogenesis and after estrogen treatment of HepG2 cells. , 1998, Carcinogenesis.

[316]  D. Clayton,et al.  Initiation of Mitochondrial DNA Replication by Transcription and R-loop Processing* , 1998, The Journal of Biological Chemistry.

[317]  E. Yeh,et al.  Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis , 1998, Oncogene.

[318]  J. Custódio,et al.  Tamoxifen inhibits induction of the mitochondrial permeability transition by Ca2+ and inorganic phosphate. , 1998, Toxicology and applied pharmacology.

[319]  G. Attardi,et al.  The mtDNA‐encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme , 1998, The EMBO journal.

[320]  M. Beal,et al.  Mitochondrial dysfunction in neurodegenerative diseases. , 1998, Biochimica et biophysica acta.

[321]  V. Procaccio,et al.  Genomic structure of the human NDUFS8 gene coding for the iron-sulfur TYKY subunit of the mitochondrial NADH:ubiquinone oxidoreductase. , 1998, Gene.

[322]  I. Scheffler,et al.  Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria. , 1998, Gene.

[323]  E. Mariman,et al.  Cloning of the human mitochondrial 51 kDa subunit (NDUFV1) reveals a 100% antisense homology of its 3'UTR with the 5'UTR of the gamma-interferon inducible protein (IP-30) precursor: is this a link between mitochondrial myopathy and inflammation? , 1998, Biochemical and biophysical research communications.

[324]  L. Garcia-Segura,et al.  Estradiol upregulates Bcl‐2 expression in adult brain neurons , 1998, Neuroreport.

[325]  C. Hoppel,et al.  Direct Inhibition of Mitochondrial Respiratory Chain Complex III by Cell-permeable Ceramide* , 1997, The Journal of Biological Chemistry.

[326]  K. Dietmeier,et al.  Differential Recognition of Preproteins by the Purified Cytosolic Domains of the Mitochondrial Import Receptors Tom20, Tom22, and Tom70* , 1997, The Journal of Biological Chemistry.

[327]  A. Colell,et al.  Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species , 1997, The Journal of Biological Chemistry.

[328]  J. Isner,et al.  Estrogen-receptor-mediated inhibition of human endothelial cell apoptosis. Estradiol as a survival factor. , 1997, Circulation.

[329]  A. Champagne,et al.  Cloning, sequencing and expression of the two genes encoding the mitochondrial single-stranded DNA-binding protein in Xenopus laevis. , 1997, Gene.

[330]  James S. Norris,et al.  Identification of genes whose expression is altered during mitosuppression in livers of ethinyl estradiol-treated female rats. , 1996, Carcinogenesis.

[331]  Y. Hatefi,et al.  Intersubunit interactions in the bovine mitochondrial complex I as revealed by ligand blotting. , 1996, Biochemical and biophysical research communications.

[332]  M. I. Lomax,et al.  Phylogenetic footprinting of the human cytochrome c oxidase subunit VB promoter. , 1996, Archives of biochemistry and biophysics.

[333]  C. Sekeris,et al.  The mitochondrion as a primary site of action of glucocorticoids: the interaction of the glucocorticoid receptor with mitochondrial DNA sequences showing partial similarity to the nuclear glucocorticoid responsive elements , 1995, The Journal of Steroid Biochemistry and Molecular Biology.

[334]  Thomas T. Y. Wang,et al.  Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. , 1995, Cancer research.

[335]  J. Larrick,et al.  Inhibition of apoptosis as a mechanism of tumor promotion , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[336]  Y. Hatefi,et al.  Catalytic sector of complex I (NADH:ubiquinone oxidoreductase): subunit stoichiometry and substrate-induced conformation changes. , 1994, Biochemistry.

[337]  R. Scarpulla,et al.  Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[338]  E. Wolvetang,et al.  Mitochondrial respiratory chain inhibitors induce apoptosis , 1994, FEBS letters.

[339]  M. I. Lomax,et al.  Structural organization of the bovine gene for the heart/muscle isoform of cytochrome c oxidase subunit VIa. , 1993, Biochimica et biophysica acta.

[340]  M. Atchison,et al.  Identification of a transcriptional initiator element in the cytochrome c oxidase subunit Vb promoter which binds to transcription factors NF-E1 (YY-1, delta) and Sp1. , 1993, The Journal of biological chemistry.

[341]  A. Maggi,et al.  Estrogen Induction of Cytochrome c Oxidase Subunit III in Rat Hippocampus , 1992, Journal of neurochemistry.

[342]  R. Scarpulla,et al.  Nuclear respiratory factor 1 activation sites in genes encoding the gamma-subunit of ATP synthase, eukaryotic initiation factor 2 alpha, and tyrosine aminotransferase. Specific interaction of purified NRF-1 with multiple target genes. , 1992, The Journal of biological chemistry.

[343]  K L Linton,et al.  Prevalence of age-related lens opacities in a population. The Beaver Dam Eye Study. , 1992, Ophthalmology.

[344]  R. Scarpulla,et al.  Transcriptional activation through ETS domain binding sites in the cytochrome c oxidase subunit IV gene , 1991, Molecular and cellular biology.

[345]  Sekeris Ce.  The mitochondrial genome: a possible primary site of action of steroid hormones. , 1990, In vivo.

[346]  R. Scarpulla,et al.  NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells. , 1990, Genes & development.

[347]  C. V. Van Itallie,et al.  Estrogen induces accumulation of the mitochondrial ribonucleic acid for subunit II of cytochrome oxidase in pituitary tumor cells. , 1988, Molecular endocrinology.

[348]  J. Mikol,et al.  Familial mitochondrial myopathy with cataract , 1980, Journal of the Neurological Sciences.

[349]  C. Haass,et al.  Mitochondrial dysfunction in Parkinson's disease. , 2010, Biochimica et biophysica acta.

[350]  T. Fox,et al.  Roles of Oxa1-related inner-membrane translocases in assembly of respiratory chain complexes. , 2009, Biochimica et biophysica acta.

[351]  Laura Conte,et al.  Biogenesis of the yeast cytochrome bc1 complex. , 2009, Biochimica et biophysica acta.

[352]  J. Yager,et al.  Mechanisms of hormone carcinogenesis: evolution of views, role of mitochondria. , 2008, Advances in experimental medicine and biology.

[353]  W. Park,et al.  Antimycin A as a mitochondrial electron transport inhibitor prevents the growth of human lung cancer A549 cells. , 2008, Oncology reports.

[354]  M. Fukushima,et al.  Proteomic analysis of the basic proteins in 5-fluorouracil resistance of human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis. , 2008, International journal of oncology.

[355]  A. MacKenzie,et al.  Estrogen suppresses uterine epithelial apoptosis by inducing birc1 expression. , 2008, Molecular endocrinology.

[356]  B. Zabłocka,et al.  [Protein kinases in mitochondria]. , 2008, Postepy biochemii.

[357]  D. Lannigan,et al.  RNA suppression of ERK 2 leads to collapse of mitochondrial membrane potential with acute oxidative stress in human lens epithelial cells , 2008 .

[358]  V. Procaccio,et al.  Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor (cid:1) in Brain Endothelial Cells , 2008 .

[359]  水町 貴諭.  Increased mitochondrial DNA induces acquired docetaxel resistance in head and neck cancer cells , 2008 .

[360]  S. Rodriguez-Cuenca,et al.  Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone. , 2007, American journal of physiology. Endocrinology and metabolism.

[361]  Ruifang Niu,et al.  Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients , 2007, IUBMB life.

[362]  Lorenzo Galluzzi,et al.  Mitochondrial membrane permeabilization in cell death. , 2007, Physiological reviews.

[363]  B. Giasson,et al.  Role of Mitochondrial Dysfunction in Parkinson’s Disease , 2007, Drugs & aging.

[364]  J. Bienkowska,et al.  Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. , 2007, Molecular endocrinology.

[365]  Adnan Erol,et al.  Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis. , 2005, Medical hypotheses.

[366]  D. Kelly,et al.  Mouse models of mitochondrial dysfunction and heart failure. , 2005, Journal of molecular and cellular cardiology.

[367]  Nobutaka Hattori,et al.  Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. , 2005, Human molecular genetics.

[368]  A. Psarra,et al.  Estrogen receptors alpha and beta (ERalpha and ERbeta) and androgen receptor (AR) in human sperm: localization of ERbeta and AR in mitochondria of the midpiece. , 2005, Human reproduction.

[369]  M. Montero,et al.  Modulation of mitochondrial Ca(2+) uptake by estrogen receptor agonists and antagonists. , 2005, British journal of pharmacology.

[370]  J. Yager,et al.  Mitochondrial localization of ERalpha and ERbeta in human MCF7 cells. , 2004, American journal of physiology. Endocrinology and metabolism.

[371]  R. Wiesner,et al.  Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells. , 2004, Nucleic acids research.

[372]  H. Fujita,et al.  17beta-estradiol suppresses ROS-induced apoptosis of CHO cells through inhibition of lipid peroxidation-coupled membrane permeability transition. , 2004, Physiological chemistry and physics and medical NMR.

[373]  Jacob H. Jacob,et al.  Journal of Carcinogenesis BioMed Central , 2003 .

[374]  J. Yager,et al.  Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors alpha and beta to human mitochondrial DNA estrogen response elements. , 2004, Journal of cellular biochemistry.

[375]  Anne-Marie Brun-Zinkernagel,et al.  Mitochondrial localization of estrogen receptor beta. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[376]  I. Goldberg,et al.  Gamma synuclein, a novel heat-shock protein-associated chaperone, stimulates ligand-dependent estrogen receptor alpha signaling and mammary tumorigenesis. , 2004, Cancer research.

[377]  J. Simpkins,et al.  Subcellular distribution of native estrogen receptor alpha and beta subtypes in cultured human lens epithelial cells. , 2004, Experimental eye research.

[378]  K. Mani,et al.  The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis , 2004 .

[379]  I. Goldberg,et al.  Stimulation of estrogen receptor signaling by gamma synuclein. , 2003, Cancer research.

[380]  S. Shin,et al.  Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors. , 2002, The Journal of biological chemistry.

[381]  I. Leav,et al.  Gene expression profiling of testosterone and estradiol-17 beta-induced prostatic dysplasia in Noble rats and response to the antiestrogen ICI 182,780. , 2002, Endocrinology.

[382]  S. Safe.  Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions. , 2001, Vitamins and hormones.

[383]  R. Boland,et al.  Subcellular distribution of native estrogen receptor alpha and beta isoforms in rabbit uterus and ovary. , 2001, Journal of cellular biochemistry.

[384]  M. Holick,et al.  Differential cellular localization of estrogen receptor alpha in uterine and mammary cells. , 2001, Molecular and cellular endocrinology.

[385]  I. Scheffler,et al.  Promoter analysis of the human succinate dehydrogenase iron-protein gene--both nuclear respiratory factors NRF-1 and NRF-2 are required. , 1998, European journal of biochemistry.

[386]  G. Miotto,et al.  Imaging the mitochondrial permeability transition pore in intact cells , 1998, BioFactors.

[387]  R. Klein,et al.  Is There Evidence of an Estrogen Effect on Age-Related Lens Opacities?: The Beaver Dam Eye Study , 1994 .

[388]  L. L. Ritter,et al.  Is there evidence of an estrogen effect on age-related lens opacities? The Beaver Dam Eye Study. , 1994, Archives of ophthalmology.

[389]  C. Sekeris.  The mitochondrial genome: a possible primary site of action of steroid hormones. , 1990, In vivo.

[390]  G. Dorn,et al.  Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death , 2022 .