Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.
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[1] S. Romano. Selectin Antagonists , 2012, Treatments in respiratory medicine.
[2] G. Wolff,et al. Physiochemical properties, safety and pharmacokinetics of bimosiamose disodium after intravenous administration. , 2005, International journal of clinical pharmacology and therapeutics.
[3] William N. Venables,et al. An Introduction To R , 2004 .
[4] E. Gelfand,et al. Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness. , 2004, American journal of respiratory cell and molecular biology.
[5] B. Jensen,et al. Pharmacoscintigraphic Comparison of HMR 1031, a VLA-4 Antagonist, in Healthy Volunteers Following Delivery Via a Nebulizer and a Dry Powder Inhaler , 2004, American journal of therapeutics.
[6] H. Boushey,et al. Effect of a single dose of the selectin inhibitor TBC1269 on early and late asthmatic responses , 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[7] R. Dixon,et al. Blockade of cell adhesion by a small molecule selectin antagonist attenuates myocardial ischemia/reperfusion injury. , 2003, European journal of pharmacology.
[8] L. Boulet,et al. The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma. , 2003, The Journal of allergy and clinical immunology.
[9] G. Wolff,et al. Development of Synthetic Pan-Selectin Antagonists: A New Treatment Strategy for Chronic Inflammation in Asthma , 2003, Pathobiology.
[10] M. Sears. Adverse effects of -agonists , 2002 .
[11] R. Dixon,et al. A Selectin Inhibitor Decreases Neutrophil Infiltration during Acute Mannheimia haemolytica Pneumonia , 2002, Veterinary pathology.
[12] P. Barnes,et al. The allergen challenge , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[13] R L Juliano,et al. Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. , 2002, Annual review of pharmacology and toxicology.
[14] P. O'Byrne,et al. Dose-dependent effects of inhaled mometasone furoate on airway function and inflammation after allergen inhalation challenge. , 2001, American journal of respiratory and critical care medicine.
[15] D. Bates,et al. Mixed-Effects Models in S and S-PLUS , 2001 .
[16] A. Coates,et al. Nebulizer choice for inhaled colistin treatment in cystic fibrosis. , 2001, Chest.
[17] K. Chung,et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response , 2000, The Lancet.
[18] M. Gimbrone,et al. E-Selectin-Dependent Signaling Via the Mitogen-Activated Protein Kinase Pathway in Vascular Endothelial Cells1 , 2000, The Journal of Immunology.
[19] P. O'Byrne,et al. Protective effects of fluticasone on allergen-induced airway responses and sputum inflammatory markers. , 2000, Canadian respiratory journal.
[20] S. Newman. Can lung deposition data act as a surrogate for the clinical response to inhaled asthma drugs? , 2000, British journal of clinical pharmacology.
[21] R. Dixon,et al. Inhibition of adhesion of human neutrophils and eosinophils to P-selectin by the sialyl Lewis antagonist TBC1269: preferential activity against neutrophil adhesion in vitro. , 2000, The Journal of allergy and clinical immunology.
[22] B. O'connor,et al. Comparison of incremental and bolus dose inhaled allergen challenge in asthmatic patients , 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[23] J. Hankinson,et al. Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. , 2000, American journal of respiratory and critical care medicine.
[24] P. Barry,et al. An in vitro analysis of the output of budesonide from different nebulizers. , 1999, The Journal of allergy and clinical immunology.
[25] L. Toledo-Pereyra,et al. Upregulation of lung chemokines associated with hemorrhage is reversed with a small molecule multiple selectin inhibitor. , 1999, Journal of the American College of Surgeons.
[26] J. Wildhaber,et al. Inhalation therapy in asthma: nebulizer or pressurized metered-dose inhaler with holding chamber? In vivo comparison of lung deposition in children. , 1999, The Journal of pediatrics.
[27] P. Barry,et al. An in vitro analysis of the output of salbutamol from different nebulizers. , 1999, The European respiratory journal.
[28] A. Zwinderman,et al. The effect of montelukast (MK‐0476), a cysteinyl leukotriene receptor antagonist, on allergen‐induced airway responses and sputum cell counts in asthma , 1999, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[29] R. Dixon,et al. Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep. , 1999, American journal of respiratory and critical care medicine.
[30] Francesco Saverio Tedesco,et al. Endothelial Cell E- and P-Selectin and Vascular Cell Adhesion Molecule-1 Function as Signaling Receptors , 1998, The Journal of cell biology.
[31] P. Barnes,et al. Allergen-induced early and late asthmatic responses are not affected by inhibition of endogenous nitric oxide. , 1998, American journal of respiratory and critical care medicine.
[32] R. Dixon,et al. Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269). , 1998, Journal of medicinal chemistry.
[33] L. Toledo-Pereyra,et al. Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion. , 1997, Journal of the American College of Surgeons.
[34] N. Choudry,et al. Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model. , 1997, The Journal of allergy and clinical immunology.
[35] G S Kansas,et al. Selectins and their ligands: current concepts and controversies. , 1996, Blood.
[36] R. Pauwels,et al. GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION , 1996 .
[37] H. Magnussen,et al. The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis. , 1996, American journal of respiratory and critical care medicine.
[38] John L. Hankinson,et al. Standardization of Spirometry, 1994 Update. American Thoracic Society. , 1995, American journal of respiratory and critical care medicine.
[39] P. O'Byrne,et al. Reproducibility of allergen-induced early and late asthmatic responses. , 1995, The Journal of allergy and clinical immunology.
[40] C. Bertozzi,et al. The selectins and their ligands. , 1994, Current opinion in cell biology.
[41] E. Scarpini,et al. Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule. , 1994, The Journal of biological chemistry.
[42] Stephen Senn,et al. Cross-over trials in clinical research , 1993 .
[43] Buist As. Standardization of spirometry. , 1987 .