The constitution of primycin. Part III. Degradation of methylated primycin, and the structure of primycin

Methylation of primycin with methyl iodide–silver oxide in dimethylformamide gives a trimethylated urea derivative and a trimethylated guanidine derivative. The cleavage of these products by ozonolysis is described. From a study of the products derived from these reactions a structure is proposed for primycin.