Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.
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A. Swensen | G. Kaczorowski | B. Priest | Haifeng Tang | B. Pio | Sophie Roy | F. Ding | Xiaoyan Zhou | A. Pasternak | Lihu Yang | E. Parmee | Melba Hernandez | Sookhee N. Ha | K. Sullivan | Brande S Thomas-Fowlkes | J. Felix | A. Shahripour | R. Brochu | K. Owens | Jinlong Jiang | Caryn Hampton | L. Pai | Shawn P. Walsh | Juliann Ehrhart | M. Alonso‐Galicia | R. D. de Jesus | M. L. García | Xin Gu | Yuping Zhu | N. Teumelsan | Timothy Bailey | Lee-yuh Pai