Antileishmanial activity of 2-amino-thiophene derivative SB-200.

[1]  Y. Pérez-Castillo,et al.  Antileishmanial Activity of Cinnamic Acid Derivatives against Leishmania infantum , 2023, Molecules.

[2]  M. Scotti,et al.  Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents. , 2023, European journal of medicinal chemistry.

[3]  J. Rocha,et al.  Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene , 2023, Pharmaceuticals.

[4]  F. Xavier,et al.  In vitro anti-Leishmania activity of new isomeric cobalt(II)complexes and in silico insights: Mitochondria impairment and apoptosis-like cell death of the parasite. , 2022, Journal of inorganic biochemistry.

[5]  P. Leprohon,et al.  Thiophene derivatives activity against the protozoan parasite Leishmania infantum , 2022, International journal for parasitology. Drugs and drug resistance.

[6]  D. Arcanjo,et al.  Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol. , 2022, Toxicology in vitro : an international journal published in association with BIBRA.

[7]  S. Kaur,et al.  Unwelcome prevalence of leishmaniasis with several other infectious diseases. , 2022, International immunopharmacology.

[8]  H. Mora-Montes,et al.  Current Models to Study the Sporothrix-Host Interaction , 2022, Frontiers in Fungal Biology.

[9]  K. Barnes,et al.  Twice neglected? Neglected diseases in neglected populations , 2021, British journal of clinical pharmacology.

[10]  Mohammed A Alaidarous,et al.  Embilica officinalis L. inhibits the growth and proliferation of Leishmania donovani through the induction of ultrastructural changes, mitochondrial dysfunction, oxidative stress and apoptosis-like cell death. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[11]  A. Fairlamb,et al.  Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity. , 2021, ACS medicinal chemistry letters.

[12]  J. Rocha,et al.  Curzerene antileishmania activity: Effects on Leishmania amazonensis and possible action mechanisms. , 2021, International immunopharmacology.

[13]  R. Schwartz,et al.  Treatment options for leishmaniasis , 2021, Clinical and experimental dermatology.

[14]  Alane Beatriz Vermelho,et al.  Identification of Chalcone Derivatives as Inhibitors of Leishmania infantum Arginase and Promising Antileishmanial Agents , 2021, Frontiers in Chemistry.

[15]  V. Binyukov,et al.  Exposition of Phosphatidylserine in Lewis Carcinoma Cells under the Action of Anphen Sodium and Hydrogen Peroxide , 2021 .

[16]  F. A. Carvalho,et al.  Antileishmanial activity of cordiaquinone E towards Leishmania (Leishmania) amazonensis. , 2020, International immunopharmacology.

[17]  A. B. Reis,et al.  Recent advances and new strategies on leishmaniasis treatment , 2020, Applied Microbiology and Biotechnology.

[18]  P. Bedi,et al.  Thiophene derivatives: A potent multitargeted pharmacological scaffold , 2020 .

[19]  E. Muratov,et al.  Computer-Assisted Design of Thiophene-Indole Hybrids as Leishmanial Agents. , 2020, Current topics in medicinal chemistry.

[20]  Karunakaran A Kalesh,et al.  Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases , 2020, RSC medicinal chemistry.

[21]  C. N. Dias,et al.  Methyl gallate: Selective antileishmanial activity correlates with host-cell directed effects. , 2020, Chemico-biological interactions.

[22]  I. Katkov,et al.  Aseptic Technology for Cryoprotectant-Free Vitrification of Human Spermatozoa by Direct Dropping into Clean Liquid Air: Apoptosis, Necrosis, Motility, and Viability , 2020, BioMed research international.

[23]  Maria Paola Costi,et al.  Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics. , 2019, European journal of medicinal chemistry.

[24]  A. Alonso,et al.  Antileishmanial and cytotoxic activities of ionic surfactants compared to those of miltefosine. , 2019, Colloids and surfaces. B, Biointerfaces.

[25]  E. S. Coimbra,et al.  A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis. , 2019, Parasitology international.

[26]  S. Sundar,et al.  Current and emerging medications for the treatment of leishmaniasis , 2019, Expert opinion on pharmacotherapy.

[27]  Márcia R. Oliveira,et al.  SB-83, a 2-Amino-thiophene derivative orally bioavailable candidate for the leishmaniasis treatment. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[28]  E. S. Coimbra,et al.  Antileishmanial activity of a 4-hydrazinoquinoline derivative: Induction of autophagy and apoptosis-related processes and effectiveness in experimental cutaneous leishmaniasis. , 2018, Experimental parasitology.

[29]  Duncan W. Wilson,et al.  An Invertebrate Host to Study Fungal Infections, Mycotoxins and Antifungal Drugs: Tenebrio molitor , 2018, Journal of fungi.

[30]  S. Croft,et al.  Leishmaniasis , 2018, The Lancet.

[31]  R. Skouta,et al.  Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major , 2018, Molecules.

[32]  Joel S. Freundlich,et al.  Naïve Bayesian Models for Vero Cell Cytotoxicity , 2018, Pharmaceutical Research.

[33]  E. S. Coimbra,et al.  Antileishmanial Activity, Cytotoxicity and Mechanism of Action of Clioquinol Against Leishmania infantum and Leishmania amazonensis Species , 2018, Basic & clinical pharmacology & toxicology.

[34]  R. J. Alves,et al.  Antileishmanial activity of a naphthoquinone derivate against promastigote and amastigote stages of Leishmania infantum and Leishmania amazonensis and its mechanism of action against L. amazonensis species , 2017, Parasitology Research.

[35]  H. Aisa,et al.  2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry. , 2017, European journal of medicinal chemistry.

[36]  M. Shadab,et al.  Apoptosis-like cell death in Leishmania donovani treated with KalsomeTM10, a new liposomal amphotericin B , 2017, PloS one.

[37]  D. Molyneux,et al.  Neglected tropical diseases: progress towards addressing the chronic pandemic , 2017, The Lancet.

[38]  Om P. S. Patel,et al.  Antileishmanial Activity of Pyrazolopyridine Derivatives and Their Potential as an Adjunct Therapy with Miltefosine. , 2017, Journal of medicinal chemistry.

[39]  P. Scott,et al.  Cutaneous leishmaniasis: immune responses in protection and pathogenesis , 2016, Nature Reviews Immunology.

[40]  M. Scotti,et al.  2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro. , 2015, European journal of medicinal chemistry.

[41]  M. Nöllmann,et al.  The fluorescence properties and binding mechanism of SYTOX green, a bright, low photo-damage DNA intercalating agent , 2015, European Biophysics Journal.

[42]  I. Krams,et al.  Trade-off between cellular immunity and life span in mealworm beetles Tenebrio molitor , 2013 .

[43]  L. Gille,et al.  Mitochondria and Trypanosomatids: Targets and Drugs , 2011, Pharmaceutical Research.

[44]  Yijun Huang,et al.  The Gewald multicomponent reaction , 2011, Molecular Diversity.

[45]  T. Gyorkos,et al.  First-Line Therapy for Human Cutaneous Leishmaniasis in Peru Using the TLR7 Agonist Imiquimod in Combination with Pentavalent Antimony , 2009, PLoS neglected tropical diseases.

[46]  I. Söderhäll,et al.  A Novel Protein Acts as a Negative Regulator of Prophenoloxidase Activation and Melanization in the Freshwater Crayfish Pacifastacus leniusculus* , 2009, Journal of Biological Chemistry.

[47]  S. Elmore.  Apoptosis: A Review of Programmed Cell Death , 2007, Toxicologic pathology.

[48]  Berend Smit,et al.  Mesoscopic models of biological membranes , 2006 .

[49]  D. Sereno,et al.  Lower Nitric Oxide Susceptibility of Trivalent Antimony-Resistant Amastigotes of Leishmania infantum , 2005, Antimicrobial Agents and Chemotherapy.

[50]  H. Reiser,et al.  Linkage analysis of the genetic determinants of T-cell IL-4 secretion, and identification of Flj20274 as a putative candidate gene , 2005, Genes and Immunity.

[51]  S. Côrte‐Real,et al.  Interaction of Leishmania (L.) chagasi with the Vero cell line. , 2004, Parasite.

[52]  Melissa A. Miller,et al.  Inducible Resistance to Oxidant Stress in the Protozoan Leishmania chagasi * , 2000, The Journal of Biological Chemistry.

[53]  C. Nathan,et al.  Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[54]  C. Bogdan,et al.  The role of nitric oxide in innate immunity , 2000, Immunological reviews.

[55]  T. van der Valk,et al.  Toxicity of scorpion venom in chick embryo and mealworm assay depending on the use of the soluble fraction versus the whole venom. , 2014, Toxicon : official journal of the International Society on Toxinology.

[56]  M. Lima,et al.  Synthesis and evaluation of the antifungal activity of 2-(substituted-amino)-4,5-dialkyl-thiophene-3- carbonitrile derivatives , 2011 .