Tissue-Specific Activities of C. elegans DAF-16 in the Regulation of Lifespan

[1]  Cori Bargmann,et al.  Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans , 2003, Nature.

[2]  Cynthia Kenyon,et al.  Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor , 2003, Science.

[3]  Gary Ruvkun,et al.  DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism , 2003, Science.

[4]  J. McElwee,et al.  Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF‐16 , 2003, Aging cell.

[5]  G. Ruvkun,et al.  daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. , 2003, Genes & development.

[6]  E. Nishida,et al.  Identification of a DAF-16 Transcriptional Target Gene, scl-1, that Regulates Longevity and Stress Resistance in Caenorhabditis elegans , 2003, Current Biology.

[7]  M. Tatar,et al.  The Endocrine Regulation of Aging by Insulin-like Signals , 2003, Science.

[8]  Matthias Blüher,et al.  Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue , 2003, Science.

[9]  Gary Ruvkun,et al.  Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes , 2003, Nature.

[10]  M. Labouesse.  [Caenorhabditis elegans]. , 2003, Medecine sciences : M/S.

[11]  Cynthia Kenyon,et al.  Timing Requirements for Insulin/IGF-1 Signaling in C. elegans , 2002, Science.

[12]  D. Hall,et al.  Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans , 2002, Nature.

[13]  A. Fraser,et al.  Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. , 2002, Genetics.

[14]  J. Apfeld,et al.  Regulation of Life-Span by Germ-Line Stem Cells in Caenorhabditis elegans , 2002, Science.

[15]  P. L. Larsen,et al.  DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs. , 2001, Journal of molecular biology.

[16]  Raymond Y. N. Lee,et al.  Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway , 2001, Current Biology.

[17]  T. Johnson,et al.  daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans , 2001, Current Biology.

[18]  T. Johnson,et al.  The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans , 2001, Current Biology.

[19]  C. Kenyon,et al.  Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling , 2001, Nature Genetics.

[20]  Leo X. Liu,et al.  Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. , 2001, Genes & development.

[21]  P. Zipperlen,et al.  Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans , 2000, Genome Biology.

[22]  P. Zipperlen,et al.  Functional genomic analysis of C. elegans chromosome I by systematic RNA interference , 2000, Nature.

[23]  Koutarou D. Kimura,et al.  Regulation of C. elegans life-span by insulinlike signaling in the nervous system. , 2000, Science.

[24]  T. Nakazawa,et al.  Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. , 2000, The Biochemical journal.

[25]  M. Ishiguro,et al.  Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans. , 2000, Biochemical and biophysical research communications.

[26]  Y Honda,et al.  The daf‐2 gene network for longevity regulates oxidative stress resistance and Mn‐superoxide dismutase gene expression in Caenorhabditis elegans , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[27]  Cynthia Kenyon,et al.  Signals from the reproductive system regulate the lifespan of C. elegans , 1999, Nature.

[28]  C. Kahn,et al.  Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes , 1999, Cell.

[29]  J. Apfeld,et al.  Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of Diapause and Life Span , 1998, Cell.

[30]  D. Riddle,et al.  Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. , 1998, Genetics.

[31]  G. Ruvkun,et al.  Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. , 1998, Genes & development.

[32]  M. Labouesse,et al.  A tissue-specific knock-out strategy reveals that lin-26 is required for the formation of the somatic gonad epithelium in Caenorhabditis elegans. , 1998, Development.

[33]  Cori Bargmann,et al.  UNC-115, a Conserved Protein with Predicted LIM and Actin-Binding Domains, Mediates Axon Guidance in C. elegans , 1998, Neuron.

[34]  C. Kenyon,et al.  daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. , 1997, Science.

[35]  G. Ruvkun,et al.  The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans , 1997, Nature.

[36]  Koutarou D. Kimura,et al.  daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. , 1997, Science.

[37]  Donald L Riddle,et al.  Genetic and Environmental Regulation of Dauer Larva Development , 1997 .

[38]  G. Ruvkun,et al.  A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans , 1996, Nature.

[39]  J. Choih,et al.  Regulation of the , 1996 .

[40]  Morris F. Maduro,et al.  Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system. , 1995, Genetics.

[41]  E. Hedgecock,et al.  The ncl-1 gene and genetic mosaics of Caenorhabditis elegans. , 1995, Genetics.

[42]  S. Melov,et al.  Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[43]  D. Riddle,et al.  Genes that regulate both development and longevity in Caenorhabditis elegans. , 1995, Genetics.

[44]  Andrew Fire,et al.  Chapter 19 DNA Transformation , 1995 .

[45]  T. Johnson,et al.  Thermotolerance of a long-lived mutant of Caenorhabditis elegans. , 1994, Journal of gerontology.

[46]  H. Horvitz,et al.  The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor. , 1994, Development.

[47]  G. Ruvkun,et al.  daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. , 1994, Genetics.

[48]  C. Kenyon,et al.  A C. elegans mutant that lives twice as long as wild type , 1993, Nature.

[49]  P. L. Larsen.  Aging and resistance to oxidative damage in Caenorhabditis elegans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[50]  J. Vanfleteren.  Oxidative stress and ageing in Caenorhabditis elegans. , 1993, The Biochemical journal.

[51]  J. Thomas,et al.  Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. , 1992, Genetics.

[52]  J. McGhee,et al.  Spatial control of gut-specific gene expression during Caenorhabditis elegans development. , 1991, Science.

[53]  R. Porter,et al.  DNA transformation. , 1988, Methods in enzymology.

[54]  R. K. Herman.  Analysis of genetic mosaics of the nematode Caneorhabditis elegans. , 1984, Genetics.

[55]  D L Riddle,et al.  The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature. , 1984, Developmental biology.

[56]  J. Sulston,et al.  The embryonic cell lineage of the nematode Caenorhabditis elegans. , 1983, Developmental biology.

[57]  D. Riddle,et al.  A pheromone influences larval development in the nematode Caenorhabditis elegans. , 1982, Science.

[58]  D. Riddle,et al.  Interacting genes in nematode dauer larva formation , 1981, Nature.

[59]  J. Sulston,et al.  Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. , 1977, Developmental biology.