Expression of Active Fluorophore Proteins in the Milk of Transgenic Pigs Bypassing the Secretory Pathway
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Z. Bősze | Z. Ivics | W. Kues | T. Talluri | W. Garrels | D. Tiedemann | Ayan Mukherjee
[1] P. Bosch,et al. One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle , 2016, Scientific Reports.
[2] Z. Izsvák,et al. Identification and re-addressing of a transcriptionally permissive locus in the porcine genome , 2015, Transgenic Research.
[3] G. Laible,et al. Adeno-associated-virus-mediated transduction of the mammary gland enables sustained production of recombinant proteins in milk , 2015, Scientific Reports.
[4] R. Klopfleisch,et al. Probiotic Treatment Decreases the Number of CD14-Expressing Cells in Porcine Milk Which Correlates with Several Intestinal Immune Parameters in the Piglets , 2015, Front. Immunol..
[5] J. Murray,et al. Genetically engineered livestock: ethical use for food and medical models. , 2015, Annual review of animal biosciences.
[6] Nathan E Lewis,et al. Systems glycobiology for glycoengineering. , 2014, Current opinion in biotechnology.
[7] P. Hartmann,et al. At the dawn of a new discovery: the potential of breast milk stem cells. , 2014, Advances in nutrition.
[8] Hongwei Song,et al. Unglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer , 2014, Scientific Reports.
[9] Z. Izsvák,et al. Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons , 2014, Nature Protocols.
[10] Z. Izsvák,et al. Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons , 2014, Nature Protocols.
[11] Z. Izsvák,et al. Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons , 2014, Nature Protocols.
[12] Y. Kuroiwa,et al. Triple Immunoglobulin Gene Knockout Transchromosomic Cattle: Bovine Lambda Cluster Deletion and Its Effect on Fully Human Polyclonal Antibody Production , 2014, PloS one.
[13] Ning Li,et al. High-Level Recombinant Human Lysozyme Expressed in Milk of Transgenic Pigs Can Inhibit the Growth of Escherichia coli in the Duodenum and Influence Intestinal Morphology of Sucking Pigs , 2014, PloS one.
[14] P. Lu,et al. Large-Scale Production of Functional Human Lysozyme in Transgenic Cloned Goats. , 2013, Journal of biotechnology.
[15] G. Laible,et al. Coupled solid phase extraction and microparticle-based stability and purity-indicating immunosensor for the determination of recombinant human myelin basic protein in transgenic milk. , 2013, Talanta.
[16] A. Deykin,et al. Use of Transgenic Animals in Biotechnology: Prospects and Problems , 2013, Acta naturae.
[17] T. Buchholz,et al. Derivation and characterization of sleeping beauty transposon-mediated porcine induced pluripotent stem cells. , 2013, Stem cells and development.
[18] H. Niemann,et al. Assessment of Fecundity and Germ Line Transmission in Two Transgenic Pig Lines Produced by Sleeping Beauty Transposition , 2012, Genes.
[19] Yong Cheng,et al. Hybrid expression cassettes consisting of a milk protein promoter and a cytomegalovirus enhancer significantly increase mammary‐specific expression of human lactoferrin in transgenic mice , 2012, Molecular reproduction and development.
[20] A. Deykin,et al. Production of human lactoferrin in animal milk. , 2012, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[21] D. Rath,et al. Genotype-Independent Transmission of Transgenic Fluorophore Protein by Boar Spermatozoa , 2011, PloS one.
[22] Z. Izsvák,et al. Germline Transgenic Pigs by Sleeping Beauty Transposition in Porcine Zygotes and Targeted Integration in the Pig Genome , 2011, PloS one.
[23] H. Farkas,et al. rhC1INH: a new drug for the treatment of attacks in hereditary angioedema caused by C1-inhibitor deficiency , 2011, Expert review of clinical immunology.
[24] Ning Li,et al. Production of recombinant human lysozyme in the milk of transgenic pigs , 2011, Transgenic Research.
[25] G. Laible,et al. On-line casein micelle disruption for downstream purification of recombinant human myelin basic protein produced in the milk of transgenic cows. , 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[26] M. Destrempes,et al. Production of recombinant albumin by a herd of cloned transgenic cattle , 2009, Transgenic Research.
[27] G. Gong,et al. Expression and characterization of bioactive recombinant human alpha-lactalbumin in the milk of transgenic cloned cows. , 2008, Journal of dairy science.
[28] Y. Liu,et al. Cattle Mammary Bioreactor Generated by a Novel Procedure of Transgenic Cloning for Large-Scale Production of Functional Human Lactoferrin , 2008, PloS one.
[29] G. Gil,et al. Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk. , 2008, Glycobiology.
[30] H. Niemann,et al. Transgenic farm animals: an update. , 2007, Reproduction, fertility, and development.
[31] S. Langermann,et al. Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning , 2007, Proceedings of the National Academy of Sciences.
[32] L. Houdebine,et al. Preparation of recombinant proteins in milk to improve human and animal health. , 2006, Reproduction, nutrition, development.
[33] Ning Li,et al. Differential Glycosylation of rhLf Expressed in the Mammary Gland of Transgenic Mice , 2006, Animal biotechnology.
[34] R. Bondurant,et al. Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland. , 2006, Journal of dairy science.
[35] D. Salamone,et al. High level expression of bioactive recombinant human growth hormone in the milk of a cloned transgenic cow. , 2006, Journal of biotechnology.
[36] M. Paape,et al. Genetically enhanced cows resist intramammary Staphylococcus aureus infection , 2005, Nature Biotechnology.
[37] F. Pieper,et al. Expression of human lactoferrin in milk of transgenic mice , 1994, Transgenic Research.
[38] J. Kamerling,et al. Influence of lactation parameters on the N-glycosylation of recombinant human C1 inhibitor isolated from the milk of transgenic rabbits. , 2004, Glycobiology.
[39] R. Bondurant,et al. Hot topic: using a stearoyl-CoA desaturase transgene to alter milk fatty acid composition. , 2004, Journal of dairy science.
[40] Akimasa Nakao,et al. Are N‐glycolylneuraminic acid (Hanganutziu–Deicher) antigens important in pig‐to‐human xenotransplantation? , 2004, Xenotransplantation.
[41] J. Kamerling,et al. N- and O-glycans of recombinant human C1 inhibitor expressed in the milk of transgenic rabbits. , 2003, Glycobiology.
[42] R. Bondurant,et al. Increased Efficiency of Transgenic Livestock Production , 2003, Transgenic Research.
[43] H. Niemann,et al. Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep , 1999, Transgenic Research.
[44] L. Houdebine. Transgenic animal bioreactors , 2004, Transgenic Research.
[45] D. Wells,et al. Cloned transgenic cattle produce milk with higher levels of β-casein and κ-casein , 2003, Nature Biotechnology.
[46] D. Wells,et al. Cloned transgenic cattle produce milk with higher levels of beta-casein and kappa-casein. , 2003, Nature Biotechnology.
[47] A. Zhu,et al. Anti‐N‐glycolylneuraminic acid antibodies identified in healthy human serum , 2002, Xenotransplantation.
[48] E. Pauwels,et al. Large scale production of recombinant human lactoferrin in the milk of transgenic cows , 2002, Nature Biotechnology.
[49] H. Jammes,et al. Potential uses of milk epithelial cells: a review. , 2002, Reproduction, nutrition, development.
[50] Y. Malykh,et al. N-Glycolylneuraminic acid in human tumours. , 2001, Biochimie.
[51] H. Meade,et al. Transgenic milk as a method for the production of recombinant antibodies , 1999, Journal of Immunological Methods.
[52] P. Visser,et al. Human acid alpha-glucosidase from rabbit milk has therapeutic effect in mice with glycogen storage disease type II. , 1999, Human molecular genetics.
[53] N. Rudolph. Biopharmaceutical production in transgenic livestock. , 1999, Trends in biotechnology.
[54] M. Wheeler,et al. Production of bovine alpha-lactalbumin in the milk of transgenic pigs. , 1998, Journal of animal science.
[55] P. Manavalan,et al. Transgenically produced human antithrombin: structural and functional comparison to human plasma-derived antithrombin. , 1998, Blood.
[56] I Wilmut,et al. Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. , 1997, Science.
[57] F. Gwazdauskas,et al. Transgenic pigs produce functional human factor VIII in milk , 1997, Nature Biotechnology.
[58] G H Smith,et al. Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal. , 1997, Tissue & cell.
[59] A. Clark,et al. Bovine beta-casein expressed in transgenic mouse milk is phosphorylated and incorporated into micelles. , 1996, Protein expression and purification.
[60] E. Wolf,et al. Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits. , 1994, Gene.
[61] H. Meade,et al. Induction of Human Tissue Plasminogen Activator in the Mammary Gland of Transgenic Goats , 1994, Bio/Technology.
[62] A. Subramanian,et al. High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[63] R. Strange,et al. Apoptotic cell death and tissue remodelling during mouse mammary gland involution. , 1992, Development.
[64] H. Rodríguez-Martínez,et al. A simple, rapid method for differential cell counts in porcine mammary secretions , 1991, Veterinary Record.
[65] I. Wilmut,et al. High Level Expression of Active Human Alpha-1-Antitrypsin in the Milk of Transgenic Sheep , 1991, Bio/Technology.
[66] F. Pieper,et al. Generation Of Transgenic Dairy Cattle Using ‘in vitro’ Embryo Production , 1991, Bio/Technology.
[67] L. Hennighausen,et al. A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[68] J. Butler,et al. Absolute and relative concentrations of immunoglobulins G, M, and A, and albumin in the lacteal secretion of sows of different lactation numbers. , 1987, American Journal of Veterinary Research.
[69] R. Palmiter,et al. Production of transgenic rabbits, sheep and pigs by microinjection , 1985, Nature.