Engineering and control of biological systems: A new way to tackle complex diseases
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Filippo Menolascina | Diego di Bernardo | Velia Siciliano | D. di Bernardo | F. Menolascina | V. Siciliano | Velia Siciliano
[1] W. Wong,et al. Focus Issue: Adding Math to the Signaling Toolkit , 2012, Science Signaling.
[2] Joel S. Bader,et al. Synthetic chromosome arms function in yeast and generate phenotypic diversity by design , 2011, Nature.
[3] M. Fussenegger,et al. An engineered epigenetic transgene switch in mammalian cells , 2004, Nature Biotechnology.
[4] James J. Collins,et al. Tunable Signal Processing in Synthetic MAP Kinase Cascades , 2011, Cell.
[5] Mario di Bernardo,et al. Analysis, design and implementation of a novel scheme for in-vivo control of synthetic gene regulatory networks , 2011, Autom..
[6] P. Bork,et al. Impact of Genome Reduction on Bacterial Metabolism and Its Regulation , 2009, Science.
[7] N. Forbes. Engineering the perfect (bacterial) cancer therapy , 2010, Nature Reviews Cancer.
[8] J. Collins,et al. Construction of a genetic toggle switch in Escherichia coli , 2000, Nature.
[9] D. Pincus,et al. In silico feedback for in vivo regulation of a gene expression circuit , 2011, Nature Biotechnology.
[10] M. Elowitz,et al. A synthetic oscillatory network of transcriptional regulators , 2000, Nature.
[11] Pamela A Silver,et al. Intron length increases oscillatory periods of gene expression in animal cells. , 2008, Genes & development.
[12] N. Forbes,et al. Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice , 2009, British Journal of Cancer.
[13] J. Collins,et al. DIVERSITY-BASED, MODEL-GUIDED CONSTRUCTION OF SYNTHETIC GENE NETWORKS WITH PREDICTED FUNCTIONS , 2009, Nature Biotechnology.
[14] D. Bernardo,et al. A Yeast Synthetic Network for In Vivo Assessment of Reverse-Engineering and Modeling Approaches , 2009, Cell.
[15] G. Barton,et al. Creation of an , 1978 .
[16] J. March,et al. Secretion of Insulinotropic Proteins by Commensal Bacteria: Rewiring the Gut To Treat Diabetes , 2008, Applied and Environmental Microbiology.
[17] François Fages,et al. Towards Real-Time Control of Gene Expression: Controlling the Hog Signaling Cascade , 2011, Pacific Symposium on Biocomputing.
[18] G. D. Gatta,et al. Systems and Synthetic biology: tackling genetic networks and complex diseases , 2009, Heredity.
[19] Christl A Donnelly,et al. Late-acting dominant lethal genetic systems and mosquito control , 2007, BMC Biology.
[20] Helga Nowotny,et al. Naked Genes: Reinventing the Human in the Molecular Age , 2011 .
[21] Timothy K Lu,et al. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy , 2009, Proceedings of the National Academy of Sciences.
[22] Richard A Fekete,et al. Toward a live microbial microbicide for HIV: commensal bacteria secreting an HIV fusion inhibitor peptide. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[23] Shuanglin Xiang,et al. Short hairpin RNA–expressing bacteria elicit RNA interference in mammals , 2006, Nature Biotechnology.
[24] J. Collins,et al. Synthetic Biology Moving into the Clinic , 2011, Science.
[25] Olivier Pourquié,et al. Vertebrate Segmentation: From Cyclic Gene Networks to Scoliosis , 2011, Cell.
[26] John C March,et al. Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model , 2010, Proceedings of the National Academy of Sciences.
[27] J. Stelling,et al. A tunable synthetic mammalian oscillator , 2009, Nature.
[28] Eduardo Sontag,et al. Load-Induced Modulation of Signal Transduction Networks , 2011, Science Signaling.
[29] Farren J. Isaacs,et al. Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement , 2011, Science.
[30] Martin Fussenegger,et al. Self-sufficient control of urate homeostasis in mice by a synthetic circuit , 2010, Nature Biotechnology.
[31] L. Tsimring,et al. A synchronized quorum of genetic clocks , 2009, Nature.
[32] Eduardo Sontag,et al. Modular cell biology: retroactivity and insulation , 2008, Molecular systems biology.
[33] Thomas H Segall-Shapiro,et al. Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome , 2010, Science.
[34] James J. Collins,et al. Dispersing biofilms with engineered enzymatic bacteriophage , 2007, Proceedings of the National Academy of Sciences.
[35] J. R. Coleman,et al. Virus Attenuation by Genome-Scale Changes in Codon Pair Bias , 2008, Science.
[36] James J. Collins,et al. A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells , 2007, Cell.
[37] E. Santero,et al. In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit , 2007, Nature Methods.
[38] Martin Fussenegger,et al. The impact of synthetic biology on drug discovery , 2009, Drug Discovery Today.
[39] C. Donnelly,et al. Field performance of engineered male mosquitoes , 2011, Nature Biotechnology.
[40] James J Collins,et al. Bacteria as control engineers. , 2011, Molecular cell.
[41] U. Alon. Network motifs: theory and experimental approaches , 2007, Nature Reviews Genetics.
[42] Timothy S. Ham,et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast , 2006, Nature.
[43] P. Dilger,et al. Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin‐2 in response to xylan , 2005, Journal of applied microbiology.
[44] Jared E. Toettcher,et al. Light-based feedback for controlling intracellular signaling dynamics , 2011, Nature Methods.
[45] Diego di Bernardo,et al. Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line , 2011, PLoS Comput. Biol..
[46] Christopher A. Voigt,et al. Environmentally controlled invasion of cancer cells by engineered bacteria. , 2006, Journal of molecular biology.
[47] Ahmad S. Khalil,et al. Synthetic biology: applications come of age , 2010, Nature Reviews Genetics.
[48] M. Elowitz,et al. Synthetic Biology: Integrated Gene Circuits , 2011, Science.
[49] P. Bork,et al. Proteome Organization in a Genome-Reduced Bacterium , 2009, Science.