Hepatitis C Virus Subverts Human Choline Kinase-α To Bridge Phosphatidylinositol-4-Kinase IIIα (PI4KIIIα) and NS5A and Upregulates PI4KIIIα Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral Replication
暂无分享,去创建一个
[1] C. Rice,et al. Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture , 2016, Nature Microbiology.
[2] S. Chen,et al. Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation , 2016, Journal of Virology.
[3] E. Bouřa,et al. Phosphatidylinositol 4-kinases: Function, structure, and inhibition. , 2015, Experimental cell research.
[4] M. Harris,et al. Hepatitis C virus NS5A: enigmatic but still promiscuous 10 years on! , 2015, The Journal of general virology.
[5] R. Bartenschlager,et al. Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land , 2014, Cell Host & Microbe.
[6] K. Konan,et al. Modulation of Hepatitis C Virus Genome Replication by Glycosphingolipids and Four-Phosphate Adaptor Protein 2 , 2014, Journal of Virology.
[7] R. De Francesco,et al. Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking. , 2014, Gastroenterology.
[8] Fang Zhang,et al. Integrative Functional Genomics of Hepatitis C Virus Infection Identifies Host Dependencies in Complete Viral Replication Cycle , 2014, PLoS pathogens.
[9] R. Bartenschlager,et al. On the history of hepatitis C virus cell culture systems. , 2014, Journal of medicinal chemistry.
[10] Julie Tan,et al. Cinderella story: PI4P goes from precursor to key signaling molecule , 2014, Critical reviews in biochemistry and molecular biology.
[11] R. Bartenschlager,et al. The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A , 2013, PLoS pathogens.
[12] S. Minogue,et al. Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks , 2013, Progress in Lipid Research.
[13] A. Siddiqui,et al. Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy , 2013, PLoS pathogens.
[14] L. Santambrogio,et al. The lipid kinase PI4KIIIβ preserves lysosomal identity , 2012, The EMBO journal.
[15] Ralf Bartenschlager,et al. Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication , 2012, PLoS pathogens.
[16] A. Siddiqui,et al. Phosphoinositides in the Hepatitis C Virus Life Cycle , 2012, Viruses.
[17] T. Balla,et al. PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity , 2012, Science.
[18] T. Balla,et al. Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms , 2012, Trends in Biochemical Sciences.
[19] R. De Francesco,et al. Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity , 2012, PLoS pathogens.
[20] Sunandini Sridhar. Lipid kinase PI4KIIIbeta preserves lysosomal identity , 2012 .
[21] G. Randall,et al. Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication , 2011, Journal of Virology.
[22] C. Burd,et al. Coordination of Golgi functions by phosphatidylinositol 4-kinases. , 2011, Trends in cell biology.
[23] A. Yalçin,et al. A Novel Small Molecule Antagonist of Choline Kinase-α That Simultaneously Suppresses MAPK and PI3K/AKT Signaling , 2011, Oncogene.
[24] Thomas Lengauer,et al. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. , 2011, Cell host & microbe.
[25] C. Cameron,et al. Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication , 2010, Cell.
[26] M. Binder,et al. Role of Annexin A2 in the Production of Infectious Hepatitis C Virus Particles , 2010, Journal of Virology.
[27] D. Lavillette,et al. Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[28] Qisheng Li,et al. A genome-wide genetic screen for host factors required for hepatitis C virus propagation , 2009, Proceedings of the National Academy of Sciences.
[29] John A. Tallarico,et al. Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication , 2009, Journal of Virology.
[30] N. Heaton,et al. Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication , 2009, Proceedings of the National Academy of Sciences.
[31] G. Kukolj,et al. Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication. , 2009, Virology.
[32] Raymond T Chung,et al. A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. , 2009, Cell host & microbe.
[33] H. Hauri,et al. Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load , 2008, The EMBO journal.
[34] Giovanni D'Angelo,et al. The multiple roles of PtdIns(4)P – not just the precursor of PtdIns(4,5)P2 , 2008, Journal of Cell Science.
[35] Seng-Lai Tan,et al. Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication? , 2007, Virology.
[36] Simon C Watkins,et al. Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER export. , 2006, Developmental cell.
[37] J. Mackenzie. Wrapping Things up about Virus RNA Replication , 2005, Traffic.
[38] R. Bartenschlager,et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome , 2005, Nature Medicine.
[39] Simon C Watkins,et al. Distinct Golgi Populations of Phosphatidylinositol 4-Phosphate Regulated by Phosphatidylinositol 4-Kinases* , 2005, Journal of Biological Chemistry.
[40] P. Várnai,et al. A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1. , 2005, Molecular biology of the cell.
[41] A. Salonen,et al. Viral RNA Replication in Association with Cellular Membranes , 2005, Current topics in microbiology and immunology.
[42] L. Heilmeyer,et al. Mammalian Phosphatidylinositol 4‐Kinases , 2003, IUBMB life.
[43] M. Lai,et al. Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. , 2002, Virology.
[44] R. Bartenschlager,et al. Replication of hepatitis C virus. , 2000, The Journal of general virology.
[45] K. Goto,et al. Cloning, Expression, and Localization of 230-kDa Phosphatidylinositol 4-Kinase (*) , 1996, The Journal of Biological Chemistry.
[46] K. Shimotohno,et al. Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome. , 1994, Biochemical and biophysical research communications.