Monitoring the Effect of Chemotherapy in a Mixed Glioma by C‐11‐Methionine PET

The effect of chemotherapy with procarbazine, CCNU, and vincristine in an anaplastic oligoastrocytoma was monitored by repeated positron emission tomography (PET) with C‐11‐methionine (C‐11‐MET). Chemotherapy caused a continuous decline of active tumor volume at a rate of approximately 2.4% per day, resulting in complete remission that persisted until the end of follow‐up at 3 years. Thus, the authors conclude that C‐11‐MET PET may be useful for monitoring chemotherapy in gliomas and deserves further study.