Management of cracked tooth using simvastatin as intracanal medicament

Cracked tooth syndrome is presented as pain associated with biting and sensitivity. Intracanal medication with simvastatin stimulates hard tissue formation at crack line, and the tooth was functioning on the follow‐ups.

[1]  A. Sahebkar,et al.  The effects of statins on dental and oral health: a review of preclinical and clinical studies , 2020, Journal of Translational Medicine.

[2]  A. Kassem,et al.  Topical simvastatin gel as a novel therapeutic modality for palatal donor site wound healing following free gingival graft procedure , 2018, Acta odontologica Scandinavica.

[3]  R. K. Celeste,et al.  The effect of statins on periodontal treatment—a systematic review with meta-analyses and meta-regression , 2018, Clinical Oral Investigations.

[4]  Hom-lay Wang,et al.  The Effect of Locally Delivered Statins on Treating Periodontal Intrabony Defects: A Systematic Review and Meta‐Analysis , 2017, Journal of periodontology.

[5]  Yuming Zhao,et al.  Simvastatin Promotes Dental Pulp Stem Cell-induced Coronal Pulp Regeneration in Pulpotomized Teeth. , 2016, Journal of endodontics.

[6]  M. Kavitha,et al.  Effect of statins with α-tricalcium phosphate on proliferation, differentiation, and mineralization of human dental pulp cells. , 2013, Journal of endodontics.

[7]  H. Hamishehkar,et al.  Simvastatin versus Calcium Hydroxide Direct Pulp Capping of Human Primary Molars: A Randomized Clinical Trial , 2013, Journal of dental research, dental clinics, dental prospects.

[8]  D. Marx,et al.  Simvastatin application to augment facial jaw bone in a dog model: pilot study. , 2011, Journal of periodontology.

[9]  Eun-Cheol Kim,et al.  Simvastatin promotes odontoblastic differentiation and expression of angiogenic factors via heme oxygenase-1 in primary cultured human dental pulp cells. , 2010, Journal of endodontics.

[10]  S. Shi,et al.  Simvastatin induces the odontogenic differentiation of human dental pulp stem cells in vitro and in vivo. , 2009, Journal of endodontics.

[11]  E. Bronkhorst,et al.  Seven-year clinical evaluation of painful cracked teeth restored with a direct composite restoration. , 2008, Journal of endodontics.

[12]  T. Nagata,et al.  Topical administration of simvastatin recovers alveolar bone loss in rats. , 2008, Journal of periodontal research.

[13]  J. E. Ailor.  Managing incomplete tooth fractures. , 2000, Journal of the American Dental Association.

[14]  B. Feiglin.  Aspects of dentinal and pulpal pain. Diagnosing dental pain. , 1994, Annals of the Royal Australasian College of Dental Surgeons.

[15]  C. Homewood.  Aspects of dentinal and pulpal pain. Force, cracks and restorative dentistry. , 1994, Annals of the Royal Australasian College of Dental Surgeons.

[16]  M. Tyas,et al.  Cracked tooth syndrome: diagnosis, treatment and correlation between symptoms and post-extraction findings. , 1990, Australian dental journal.

[17]  M. Brännström.  The Hydrodynamic Theory of Dentinal Pain: Sensation in Preparations, Caries, and the Dentinal Crack Syndrome , 1986 .

[18]  M. Brännström,et al.  The hydrodynamic theory of dentinal pain: sensation in preparations, caries, and the dentinal crack syndrome. , 1986, Journal of endodontics.

[19]  H. Pitkow,et al.  Basic and Clinical Pharmacology , 1983 .